Zobrazeno 1 - 10
of 25
pro vyhledávání: '"F George Otieno"'
Autor:
Struan F A Grant, Mingyao Li, Jonathan P Bradfield, Cecilia E Kim, Kiran Annaiah, Erin Santa, Joseph T Glessner, Tracy Casalunovo, Edward C Frackelton, F George Otieno, Julie L Shaner, Ryan M Smith, Marcin Imielinski, Andrew W Eckert, Rosetta M Chiavacci, Robert I Berkowitz, Hakon Hakonarson
Publikováno v:
PLoS ONE, Vol 3, Iss 3, p e1746 (2008)
Recently an association was demonstrated between the single nucleotide polymorphism (SNP), rs9939609, within the FTO locus and obesity as a consequence of a genome wide association (GWA) study of type 2 diabetes in adults. We examined the effects of
Externí odkaz:
https://doaj.org/article/23d313cfac7d4c49879d454db897a2d9
Autor:
Joseph T. Glessner, Munir E. Khan, Xiao Chang, Yichuan Liu, F. George Otieno, Maria Lemma, Isabella Slaby, Heather Hain, Frank Mentch, Jin Li, Charlly Kao, Patrick M. A. Sleiman, Michael E. March, John Connolly, Hakon Hakonarson
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background Neurodevelopmental disorders (NDDs), such as attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), are examples of complex and partially overlapping phenotypes that often lack definitive corroborating
Externí odkaz:
https://doaj.org/article/b1950642f94a49809f8e4e46bdf5f5ad
Autor:
Haitao Zhang, Cecilia E. Kim, Joseph T. Glessner, Mingyao Li, F. George Otieno, Julie L. Shaner, Rosetta M. Chiavacci, Hakon Hakonarson, Ryan M. Smith, Kiran Annaiah, Edward C. Frackelton, Robert I. Berkowitz, Struan F.A. Grant, Jonathan P. Bradfield, Kai Wang, Maria Garris, Kelly A. Thomas, Jianhua Zhao
Publikováno v:
Obesity. 17:2254-2257
The prevalence of obesity in children and adults in the United States has increased dramatically over the past decade. Besides environmental factors, genetic factors are known to play an important role in the pathogenesis of obesity. A number of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbd9792bc2f113ca293c539fdf4bb78
https://doi.org/10.1038/oby.2009.159
https://doi.org/10.1038/oby.2009.159
Autor:
Rosetta M. Chiavacci, Cuiping Hou, Jonathan P. Bradfield, Haitao Zhang, Kelly A. Thomas, Cecilia E. Kim, Maria Garris, Joseph T. Glessner, Mingyao Li, Robert I. Berkowitz, Hakon Hakonarson, Edward C. Frackelton, F. George Otieno, Struan F.A. Grant, Patrick M. A. Sleiman, Kiran Annaiah, Jianhua Zhao, Kai Wang, Wendy Glaberson
Publikováno v:
Diabetes
OBJECTIVE A number of studies have found that reduced birth weight is associated with type 2 diabetes later in life; however, the underlying mechanism for this correlation remains unresolved. Recently, association has been demonstrated between low bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c437c5e75de8c2d82509bee3a7729935
https://doi.org/10.2337/db09-0506
https://doi.org/10.2337/db09-0506
Autor:
Kai Wang, Rosetta M. Chiavacci, Kiran Annaiah, Ryan M. Smith, Hakon Hakonarson, Kelly A. Thomas, Maria Garris, Erin Santa, Marcin Imielinski, Struan F.A. Grant, Cecilia E. Kim, Jonathan P. Bradfield, Julie L. Shaner, Joseph T. Glessner, Mingyao Li, Robert I. Berkowitz, F. George Otieno, Edward C. Frackelton, Haitao Zhang
Publikováno v:
Obesity. 17:1461-1465
Recently a modest, but consistently, replicated association was demonstrated between obesity and the single nucleotide polymorphism (SNP), rs17782313, 3’ of the MC4R locus as a consequence of a meta-analysis of genome wide association (GWA) studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c097762dc1228f41bfb9b1ae9dc8b299
https://doi.org/10.1038/oby.2009.53
https://doi.org/10.1038/oby.2009.53
Autor:
F. George Otieno, Struan F.A. Grant, Andrew W. Eckert, Kathleen E. Sullivan, Rosetta M. Chiavacci, Marcin Imielinski, Ryan M. Smith, Julie L. Shaner, Michelle Petri, Hakon Hakonarson, Edward C. Frackelton, Joseph T. Glessner, Erin Santa, Jonathan P. Bradfield, Kiran Annaiah, Cecilia E. Kim
Publikováno v:
The Application of Clinical Genetics. 2:1-5
Recently an association was demonstrated between the single nucleotide polymorphism (SNP), rs10516487, within the B-cell gene BANK1 and systemic lupus erythematosus (SLE) as a consequence of a genome wide association study of this disease in European
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b9493dcfd0cdc715972038754641c80
https://doi.org/10.2147/tacg.s4089
https://doi.org/10.2147/tacg.s4089
Autor:
David A. Piccoli, Tara Willson, Robert W. Grundmeier, Jonathan P. Bradfield, Dimitri S. Monos, Rosetta M. Chiavacci, Ryan M. Smith, Patrick M. A. Sleiman, Struan F.A. Grant, Petar Mamula, Cecilia E. Kim, Edward C. Frackelton, Joseph T. Glessner, Salvatore Cucchiara, Stephen L. Guthery, Gitit Tomer, Subra Kugathasan, Erin Bonkowski, Andrew W. Eckert, Robert N. Baldassano, Erin Santa, Vito Annese, Kiran Annaiah, Marcin Imielinski, Debra J. Abrams, Lee A. Denson, Julie L. Shaner, Hakon Hakonarson, F. George Otieno, Nicholas Peterson
Publikováno v:
Nature Genetics. 40:1211-1215
Inflammatory bowel disease (IBD) is a common inflammatory disorder with complex etiology that involves both genetic and environmental triggers, including but not limited to defects in bacterial clearance, defective mucosal barrier and persistent dysr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51fc77f2c0dd77d45f89b75aa8172895
https://doi.org/10.1038/ng.203
https://doi.org/10.1038/ng.203
Autor:
Cecilia E. Kim, Tracy Casalunovo, Marcella Devoto, F. George Otieno, Struan F.A. Grant, Robert N. Baldassano, Rosetta M. Chiavacci, Debra J. Abrams, Ryan M. Smith, Luke J. Robinson, Chioma C. Onyiah, Dimitri S. Monos, Julie L. Shaner, Stathis Kanterakis, Jonathan P. Bradfield, Hakon Hakonarson, Robert Skraban, Edward C. Frackelton, Joseph T. Glessner, Andrew W. Eckert
Publikováno v:
Clinical Gastroenterology and Hepatology. 5:972-976
Background & Aims: Recently an association was shown between the single nucleotide polymorphism (SNP), rs11209026, within the interleukin-23 receptor ( IL23R ) locus and Crohn's disease (CD) as a consequence of a genome-wide association study of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72937a07e41bc3beb39e86ced72b0b9b
https://doi.org/10.1016/j.cgh.2007.04.024
https://doi.org/10.1016/j.cgh.2007.04.024
Autor:
Struan Fa, Grant, Michelle, Petri, Jonathan P, Bradfield, Cecilia E, Kim, Erin, Santa, Kiran, Annaiah, Edward C, Frackelton, Joseph T, Glessner, F George, Otieno, Julie L, Shaner, Ryan M, Smith, Andrew W, Eckert, Rosetta M, Chiavacci, Marcin, Imielinski, Kathleen E, Sullivan, Hakon, Hakonarson
Publikováno v:
The Application of Clinical Genetics
Recently an association was demonstrated between the single nucleotide polymorphism (SNP), rs10516487, within the B-cell gene BANK1 and systemic lupus erythematosus (SLE) as a consequence of a genome wide association study of this disease in European
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58f17c154874f70f0a68fe5f3a1c526b
https://pubmed.ncbi.nlm.nih.gov/23776345
https://pubmed.ncbi.nlm.nih.gov/23776345
Autor:
Kai Wang, Cuiping Hou, Maria Garris, Joseph T. Glessner, Cecilia E. Kim, Mingyao Li, Jonathan P. Bradfield, Patrick M. A. Sleiman, F. George Otieno, Rosetta M. Chiavacci, Struan F.A. Grant, Robert I. Berkowitz, Brendan J. Keating, Edward C. Frackelton, Jianhua Zhao, Kelly A. Thomas, Sandra Deliard, Frank D. Mentch, Haitao Zhang, Hakon Hakonarson
Publikováno v:
BMC Medical Genetics, Vol 11, Iss 1, p 96 (2010)
BMC Medical Genetics
BMC Medical Genetics
Background Human height is considered highly heritable and correlated with certain disorders, such as type 2 diabetes and cancer. Despite environmental influences, genetic factors are known to play an important role in stature determination. A number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0ad64506b1e9f54f9b967cf18beb75
http://www.biomedcentral.com/1471-2350/11/96
http://www.biomedcentral.com/1471-2350/11/96