Zobrazeno 1 - 10
of 32
pro vyhledávání: '"F G van der Goot"'
Autor:
I. Castanon, J. T. Hannich, L. Abrami, F. Huber, M. Dubois, M. Müller, F. G. van der Goot, M. Gonzalez-Gaitan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
During development, oriented cell division is important to proper body axis extension. Here, the authors show that sphingolipids are required to direct spindle rotation and oriented mitosis via Anthrax receptor palmitoylation in zebrafish gastrulatio
Externí odkaz:
https://doaj.org/article/8a8ca64a3ec14891b6839f3bf319ba3c
Autor:
F. G. van der Goot, Martina Audagnotto, Sylvia Ho, M. Anward, Laurence Abrami, Maria J. Marcaida, Florence Pojer, M. Dal Peraro, Giulia Fonti, Patrick A. Sandoz, Francisco Mesquita
Many biochemical reactions occur at the membrane interfaces. The proper control of these reactions requires spatially and temporally controlled recruitment of protein complexes. These assemblies are largely regulated by post-translational modificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b14a6af6de54544e39e26fcdce16529
https://doi.org/10.1101/2020.06.18.157545
https://doi.org/10.1101/2020.06.18.157545
Autor:
F. G. van der Goot, Yulia Tsitrin, Marie-Claire Velluz, Patrick Paumard, Catherine El Bez, Michael W. Parker, Salvatore Lanzavecchia, Jacques Dubochet, Marc Adrian, Craig J. Morton
Publikováno v:
Nature Structural Biology. 9:729-733
Proteins exist in one of two generally incompatible states: either membrane associated or soluble. Pore-forming proteins are exceptional because they are synthesized as a water-soluble molecule but end up being located in the membrane -- that is, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87f6495c8d77e7ef1da2d32d2a2c6d9
https://doi.org/10.1038/nsb839
https://doi.org/10.1038/nsb839
Publikováno v:
Journal of Biological Chemistry, Vol. 273, No 29 (1998) pp. 18122-18129
Aerolysin is a pore-forming toxin that plays a key role in the pathogenesis of Aeromonas hydrophila infections. In this study, we have analyzed the effect of aerolysin on human granulocytes (HL-60 cells). Proaerolysin could bind to these cells, was p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba74906dfea5d4d02b23b6da2fde8ed
https://doi.org/10.1074/jbc.273.29.18122
https://doi.org/10.1074/jbc.273.29.18122
Autor:
Susanne C. Feil, S M Raja, Jamie Rossjohn, J T Buckley, Michael W. Parker, F. G. van der Goot, K L Nelson
Publikováno v:
Biochemistry, Vol. 37, No 2 (1998) pp. 741-746
Aerolysin is a channel-forming toxin that must oligomerize in order to become insertion-competent. Modeling based on the crystal structure of the proaerolysin dimer and electron microscopic images of the oligomer indicated that a loop in domain 3 mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab20845f1247e1de2cd4c660c2651f7c
https://doi.org/10.1021/bi9721039
https://doi.org/10.1021/bi9721039
Autor:
I. Castanon, L. Abrami, L. Holtzer, C. P. Heisenberg, F. G. van der Goot, M. Gonzxe1lez-Gaitxe1n
Publikováno v:
NATURE CELL BIOLOGY, Volume 1,5 Number 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=erc_________::ab3a808e13b16ba4ed45ab6ba4ff304a
Autor:
Thomas Harder, F. G. van der Goot
Publikováno v:
Seminars in immunology. 13(2)
While the existence of cholesterol/sphingolipid (raft) membrane domains in the plasma membrane is now supported by strong experimental evidence, the structure of these domains, their size, their dynamics, and their molecular composition remain to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b44654c33c572bbbb2d8460bf25de360
https://pubmed.ncbi.nlm.nih.gov/11308292
https://pubmed.ncbi.nlm.nih.gov/11308292
Publikováno v:
Nature. 354:408-410
THE 'molten' globular conformation of a protein is compact with a native secondary structure but a poorly defined tertiary structure1,2. Molten globular states are intermediates in protein folding and unfolding3–5 and they may be involved in the tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dfe29cd5dcf5c169c6cb980a914be6
https://doi.org/10.1038/354408a0
https://doi.org/10.1038/354408a0
Autor:
M, Hribar, A, Bloc, F G, van der Goot, L, Fransen, P, De Baetselier, G E, Grau, H, Bluethmann, M A, Matthay, Y, Dunant, J, Pugin, R, Lucas
Publikováno v:
European journal of immunology. 29(10)
Herein, we show that TNF exerts a pH-dependent increase in membrane conductance in primary lung microvascular endothelial cells and peritoneal macrophages. This effect was TNF receptor-independent, since it also occurred in cells isolated from mice d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::196caf7bf23bb66bb9bda68ce4babb17
https://pubmed.ncbi.nlm.nih.gov/10540321
https://pubmed.ncbi.nlm.nih.gov/10540321
Publikováno v:
Biochemistry, Vol. 38, No 14 (1999) pp. 4296-4302
The alpha-toxin from Staphylococcus aureus undergoes several conformational changes from the time it is released from the bacterium to the moment it forms a channel in the plasma membrane of its target cell. It is initially a soluble monomer, which u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b3c05724296f4f8583263f5c283cf9e
https://pubmed.ncbi.nlm.nih.gov/10194347
https://pubmed.ncbi.nlm.nih.gov/10194347