Zobrazeno 1 - 8
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pro vyhledávání: '"F G Roberge"'
Publikováno v:
The Journal of Immunology. 154:922-927
Immunosuppressive drugs currently available for the treatment of autoimmune diseases display a narrow therapeutic window between efficacy and toxic side effects. The use of combinations of drugs that have a synergistic effect may expand this window a
Publikováno v:
Investigative ophthalmologyvisual science. 38(1)
Transforming growth factor beta-1 (TGF beta-1) can modulate inflammation. Endotoxin-induced uveitis (EIU) is characterized by acute ocular inflammation related to the release of cytokines, including interleukin (IL)-6. The authors investigated the ef
Publikováno v:
The British journal of ophthalmology. 80(7)
AIMS/BACKGROUND: The subcutaneous injection of bacterial endotoxin in Lewis rats produces an acute intraocular inflammation evolving over a 24 hour period. This endotoxin induced uveitis (EIU) is characterised by a biphasic protein exudation and a ce
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(4)
We studied the effect of nitric oxide (NO) production on the evolution of toxoplasmosis in C57BL/6 mice. Infection was induced by i.p. injection of Toxoplasma gondii strain ME49. NO synthesis was inhibited by treatment with aminoguanidine, a structur
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(2)
Immunosuppressive drugs currently available for the treatment of autoimmune diseases display a narrow therapeutic window between efficacy and toxic side effects. The use of combinations of drugs that have a synergistic effect may expand this window a
Autor:
R R Caspi, F G Roberge, C G McAllister, M el-Saied, T Kuwabara, I Gery, E Hanna, R B Nussenblatt
Publikováno v:
The Journal of Immunology. 136:928-933
Long-term S-antigen (S-Ag)-specific T lymphocyte lines were derived from the lymph nodes of immunized Lewis rats that had been pretreated with low-dose cyclophosphamide. The protocol consisted of functional selection by alternating cycles of stimulat
Autor:
R R Caspi, F G Roberge, C C Chan, B Wiggert, G J Chader, L A Rozenszajn, Z Lando, R B Nussenblatt
Publikováno v:
The Journal of Immunology. 140:1490-1495
Experimental autoimmune uveoretinitis (EAU) is an organ-specific, T lymphocyte-mediated autoimmune disease, which serves as a model for several human ocular inflammations of an apparently autoimmune nature. EAU pathology in some rodents and in monkey
Publikováno v:
The Journal of Immunology. 140:2193-2196
The Müller cell is the major glial element of the mammalian retina. It can be induced to express MHC class II determinants in culture, when exposed to supernatant from activated lymphocytes. In an in vitro co-culture system, Müller cells had been s