Zobrazeno 1 - 10
of 23
pro vyhledávání: '"F G Joslin"'
Publikováno v:
The Journal of Immunology. 147:1530-1536
Human monocytes may synthesize simultaneously both the agonist IL-1 beta and a specific receptor antagonist of IL-1 (IL-1ra). These studies examined whether monocyte production of these two structurally related cytokines was regulated differently. IL
Publikováno v:
The Journal of Immunology. 145:2161-2166
Human monocytes aged in medium exhibit a decrease in LPS-induced IL-1 beta production in comparison with fresh cells. The objective of these experiments was to evaluate the effects of differentiation for 1 or 6 days in IFN-gamma, 1,25-(OH)2-vitamin D
Publikováno v:
Clinical & Experimental Immunology; Dec1988, Vol. 74 Issue 3, p377-381, 5p
Publikováno v:
The Journal of Immunology. 143:1851-1858
Previous studies have described a 22 kD IL-1 inhibitor in the supernatant of human monocytes cultured on adherent immune complexes (J. Immunol. 134:3868, 1985). The studies reported herein further detail the conditions of production and biological pr
Publikováno v:
Scandinavian Journal of Immunology. 15:63-70
A solid-phase assay for anti-histone antibodies is described, in which antibodies bound to calf thymus total histones, specific histone classes, or chromatin were detected by radioactive anti-human IgG, IgA or IgM. The reactivity of human sera from v
Publikováno v:
The Journal of Immunology. 131:269-274
Anti-histone antibodies have been demonstrated in the sera of patients with both idiopathic and drug-induced lupus. We measured anti-histone antibodies in female NZB/NZW (F1) mice, which are considered to be a model of human SLE. Using a sensitive an
Publikováno v:
The Journal of Immunology. 143:118-126
Cultured human monocytes and tissue macrophages exhibit a marked decrease in LPS-stimulated IL-1 production. Preincubation of monocytes in 100 U/ml IFN-gamma or in 0.25 microgram/ml cycloheximide (Cx) leads to a partial maintenance of the ability to
Publikováno v:
The Journal of Immunology. 134:3868-3875
The objective of these studies was to examine the ability of phorbol myristic acetate (PMA), Fc fragments, and various forms of immune complexes to induce the production by human monocytes of factors stimulatory to chondrocytes or thymocytes. All of
Publikováno v:
Proceedings of the National Academy of Sciences. 62:144-149
No explanation has been available concerning the γ globulin defect in a unique family with one member whose serum was devoid of all the usual Gm genetic antigens. In the present study, it was found that this serum lacks ordinary γG1 and γG3 protei
Publikováno v:
The Journal of Experimental Medicine
Two types of γG4 proteins, termed 4a and 4b, were characterized through antigenic studies of myeloma proteins. Both were recognized by specific antigens on the Fc fragment which were shared with other γG classes. The distinctive antigen of the comm