Výsledky vyhledávání - "F G, Spinale"

Amlodipine Monotherapy, Angiotensin-Converting Enzyme Inhibition, and Combination Therapy With Pacing-Induced Heart Failure

Autor: Mark J. Clair, Ward V. Houck, Scott B. Kribbs, W. M. Merritt, R Mukherjee, M G Dodd, R S Krombach, F G Spinale

Publikováno v: Hypertension. 31:755-765

Abstract —In patients with congestive heart failure (CHF) receiving therapy with angiotensin-converting enzyme (ACE) inhibition, institution of calcium channel antagonism with amlodipine provided favorable effects. The goal of the present study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d65868c1329a6805d4bdc60cc4ca542
https://doi.org/10.1161/01.hyp.31.3.755

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Myocardial electrophysiological properties in the presence of an AT1 angiotensin II receptor antagonist

Autor: M. H. Cox, S. J. O, M. Gasparo, R. Mukherjee, K. W. Hewett, F. G. Spinale

Publikováno v: Basic Research in Cardiology. 92:129-138

Blockade of the AT1 angiotensin II (Ang II) receptor has been shown to provide anti-hypertensive effects. However, whether AT1 Ang II receptor antagonists influence myocardial electrophysiological properties remains unclear.Accordingly, atrial and ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff812a893e36ba60cc5cdf4d5669bc3
https://doi.org/10.1007/bf00788630

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Spatial characterization of contracting cardiac myocytes by computer-assisted, video-based image processing

Autor: R. Mukherjee, F. G. Spinale, Z. Wang, C. F. Lam

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 270:H769-H779

The goals of the present study were to develop and validate a computer-assisted, video-based image processing (CAVIP) system to measure time-dependent changes in isolated myocyte geometry during contraction and to use the CAVIP system to examine spat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f61a3c4665158c5835ed1a747cf78974
https://doi.org/10.1152/ajpheart.1996.270.2.h769

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The effect of neuromuscular blockade on mask ventilation

Autor: R D, Warters, T A, Szabo, F G, Spinale, S M, DeSantis, J G, Reves

Publikováno v: Anaesthesia. 66(3)

We wished to test the hypothesis that neuromuscular blockade facilitates mask ventilation. In order reliably and reproducibly to assess the efficiency of mask ventilation, we developed a novel grading scale (Warters scale), based on attempts to gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cacbd5dc561c24e796f07e9640d661f5
https://pubmed.ncbi.nlm.nih.gov/21568989

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Potential role of endothelin receptor antagonists in the setting of cardiopulmonary bypass: relevance to myocardial performance

Autor: A, Ergul, C, Joffs, A C, Walker, F G, Spinale

Publikováno v: Heart failure reviews. 6(4)

The ET system is activated in cardiac surgical setting as evidenced by elevated systemic and myocardial ET-1 levels after coronary bypass grafting surgery which requires hypothermic cardioplegic arrest and cardiopulmonary bypass. Increased ET-1 may i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::386b43cb43a9fb7c05cabb47ab709612
https://pubmed.ncbi.nlm.nih.gov/11447303

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Selective vasopressin, angiotensin II, or dual receptor blockade with developing congestive heart failure

Autor: M J, Clair, M K, King, A T, Goldberg, J W, Hendrick, R, Nisato, D M, Gay, A E, Morrison, J H, McElmurray, R S, Krombach, B R, Bond, C, Cazaubon, D, Nisato, F G, Spinale

Publikováno v: The Journal of pharmacology and experimental therapeutics. 293(3)

With developing congestive heart failure (CHF), activation of the vasopressin V(1a) and angiotensin II type 1 (AT(1)) receptors can occur. In the present study, we examined the direct effects of V(1a) receptor blockade (V(1a) block), selective AT(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::04dedd7824355bdcf7cb001da57ac8fd
https://pubmed.ncbi.nlm.nih.gov/10869385

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ATP-sensitive potassium channel activation before cardioplegia. Effects on ventricular and myocyte function

Autor: B H, Dorman, L, Hebbar, J L, Zellner, R B, New, W V, Houck, J, Acsell, C, Nettles, J W, Hendrick, A P, Sampson, R, Mukherjee, F G, Spinale

Publikováno v: Circulation. 98

Pretreatment with potassium channel openers (PCOs) has been shown to provide protective effects in the setting of myocardial ischemia. The goal of the present study was to examine whether PCO pretreatment would provide protective effects on left vent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28b25b82bbdbdc09b2fa3bd9e0aaa5bc
https://pubmed.ncbi.nlm.nih.gov/9852901

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Angiotensin-converting enzyme inhibition and angiotensin II subtype-1 receptor blockade during the progression of left ventricular dysfunction: differential effects on myocyte contractile processes

Autor: F G, Spinale, H H, Holzgrefe, R, Mukherjee, M L, Webb, R B, Hird, M J, Cavallo, J R, Powell, W H, Koster

Publikováno v: The Journal of pharmacology and experimental therapeutics. 283(3)

Inhibition of the angiotensin-converting enzyme (ACE) in the setting of chronic left ventricular (LV) dysfunction has been demonstrated to have beneficial effects on survival and symptoms. However, whether ACE inhibition has direct effects on myocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d0e72ce4610427ed2a2f7429bc1d6a2
https://pubmed.ncbi.nlm.nih.gov/9399980

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