Zobrazeno 1 - 10
of 21
pro vyhledávání: '"F E Dorer"'
Publikováno v:
Hypertension. 6:374-382
Spleen cells from mice immunized with partially purified hog kidney renin were fused with mouse myeloma cells to produce a stable monoclonal hybridoma cell line that synthesizes an antibody against renin. A single monoclonal antibody was chosen for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b8ad0bcd8ff1b1dd9ee64895310d97
https://doi.org/10.1161/01.hyp.6.3.374
https://doi.org/10.1161/01.hyp.6.3.374
Publikováno v:
Circulation Research. 34:824-827
Two dipeptides, phenylalanylarginine (Phe-Arg) and serylproline (Ser-Pro), are released sequentially from bradykinin by angiotensin-converting enzyme purified from hog lungs; chloride increases the rate of release of both dipeptides. Using an automat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad1b7a6af4c7d6f59dfa831ce5c8782
https://doi.org/10.1161/01.res.34.6.824
https://doi.org/10.1161/01.res.34.6.824
Publikováno v:
Circulation Research. 37:715-724
An investigation into the mechanism that sustains the blood pressure in chronic one-kidney hypertension in rabbits was made using passive and active immunization with hog kidney extracts containing renin and with angiotensin antagonists. Seven hypert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7f8fd155aec8b645f8a9f8215d3700
https://doi.org/10.1161/01.res.37.6.715
https://doi.org/10.1161/01.res.37.6.715
Publikováno v:
Journal of Biological Chemistry. 253:3140-3142
Cathepsin D, purified from hog spleen, releases angiotensin I from tetradecapeptide renin substrate and from protein renin substrates purified from hog and human plasma. However, the enzyme does not act on the naturally occurring renin substrate as i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ece03d5fc6edd93b3c79e1b192308ec8
https://doi.org/10.1016/s0021-9258(17)40814-3
https://doi.org/10.1016/s0021-9258(17)40814-3
Publikováno v:
The Journal of biological chemistry. 253(9)
Cathepsin D, purified from hog spleen, releases angiotensin I from tetradecapeptide renin substrate and from protein renin substrates purified from hog and human plasma. However, the enzyme does not act on the naturally occurring renin substrate as i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::424bc7f6ac736c78e22befca6d33976e
https://pubmed.ncbi.nlm.nih.gov/641059
https://pubmed.ncbi.nlm.nih.gov/641059
Publikováno v:
Experientia. 34(11)
Arg-Pro-Pro-Gly-Phe, the N-terminal pentapeptide of bradykinin, is not an inhibitor of angiotensin-converting enzyme and is not hydrolyzed by the enzyme. Arg-Pro-Pro, the N-terminal tripeptide is a relatively potent (IC50 = 2.3 X 10(6) M) inhibitor b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f76e1441abc882d224388d55569a62
https://pubmed.ncbi.nlm.nih.gov/214326
https://pubmed.ncbi.nlm.nih.gov/214326
Publikováno v:
Federation proceedings. 36(5)
Although the role of renin in hypertension continues to be incompletely defined, recent progress in the chemistry of renin has been considerable. Extensive purifications of hog kidney renin and the renin-like mouse submaxillary gland enzyme have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db0d4963149c89b0cc76ffd6aaacf002
https://pubmed.ncbi.nlm.nih.gov/14850
https://pubmed.ncbi.nlm.nih.gov/14850
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 83(3)
Renin substrate (angiotensinogen) in unfractionated human plasma has been shown to exist in multiple forms by DEAE-cellulose chromatography and isoelectric focusing. Two major and 5 to 6 minor peaks were resolved by using a descending pH gradient elu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90e9b09dc60fdb54ec9cd68ca7df7a3
https://pubmed.ncbi.nlm.nih.gov/624180
https://pubmed.ncbi.nlm.nih.gov/624180
Autor:
Leonard T. Skeggs, F E Dorer
Publikováno v:
American journal of hypertension. 2(10)
Our previous work has shown that pure hog renin, when injected into one-kidney, one-clip hypertensive rabbits elicits not only antirenin antibodies but also antibodies to what appears to be an altered form of renin (antigen M). Antiantigen M stains t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e188c1e839749262f90b9c71778e2b
https://pubmed.ncbi.nlm.nih.gov/2679772
https://pubmed.ncbi.nlm.nih.gov/2679772
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 7(1)
The renin-angiotensin system does not appear to be involved in the maintenance of elevated blood pressure in experimental one-kidney, one clip hypertension. Paradoxically, direct immunization with purified hog kidney renin lowers the blood pressure o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1db79d5814c4cc8296d828b0c4d953b
https://pubmed.ncbi.nlm.nih.gov/3884500
https://pubmed.ncbi.nlm.nih.gov/3884500