Zobrazeno 1 - 10
of 185
pro vyhledávání: '"F E, samson"'
Publikováno v:
Restorative neurology and neuroscience. 13(3-4)
Traumatic injury of the adult optic nerve causes a progressive degeneration of retinal ganglion cells. Despite this ongoing degeneration, a partial recovery of visual behavioral function and of local cerebral glucose use (LCGU) has been observed. To
Autor:
F E, Samson, S R, Nelson
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 46(4)
In this overview we bring together certa in facts and concepts that support the theory that the aging of "disease-free" brain is a consequence of the accumulated cellular-molecular modifications caused by oxygen free radicals. The relevance of transi
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 46(3)
Global hypoxia preconditioning provides neuroprotection against a subsequent, normally damaging challenge. While the mechanistic pathways are unknown, changes in the expression of stress-related proteins are implicated. Hypoxia preconditioning attenu
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 46(3)
A sensitive iron assay was developed for measuring non-heme and loosely bound iron in regions of rat brain. The method is based on the salicylate trapping of hydroxyl radicals generated from ascorbate-driven redox cycling of Fe3+-EDTA. This assay has
Publikováno v:
Neurochemical research. 22(6)
Microdialysis probe insertion into rat cerebral cortex significantly affects the levels of redox-active substances in brain extracellular fluid. Ascorbic acid levels are high immediately after probe insertion, decline rapidly, and then rise as the ra
Publikováno v:
Proceedings of the Western Pharmacology Society. 35
Publikováno v:
Progress in clinical and biological research. 351
Publikováno v:
Neurotoxicology. 11(1)
[3H]Quinuclidinyl benzilate (QNB) binding to muscarinic receptors decreased in the rat forebrain after convulsions induced by a single dose of either soman, a potent inhibitor of acetylcholinesterase, or kainic acid, an excitotoxin. A Rosenthal plot
Publikováno v:
European Journal of Pharmacology. 183:1541-1542
Publikováno v:
European Journal of Pharmacology. 142:215-224
Diazepam's impact on kainic acid seizure-induced local cerebral glucose utilization (LCGU) was assessed by a quantitative [14C]2-deoxyglucose method. Male rats were injected i.p. with either kainic acid (12 mg/kg) or its vehicle, 3 or 48 h before LCG