Zobrazeno 1 - 10
of 35
pro vyhledávání: '"F E, Cohen"'
Publikováno v:
Journal of Biological Chemistry. 268:15983-15993
On the basis of its primary sequence and the location of its disulfide bonds, we propose a structural model of the erythropoietic hormone erythropoietin (Epo) which predicts a four alpha-helical bundle motif, in common with other cytokines. In order
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21cbd4f4f66d0a18b483c1651cca8ea1
https://doi.org/10.1016/s0021-9258(18)82348-1
https://doi.org/10.1016/s0021-9258(18)82348-1
Publikováno v:
Current topics in microbiology and immunology. 269
The ubiquitous, opportunistic pathogen human cytomegalovirus (CMV) encodes several proteins homologous to those of the host organism. Four different CMV genes encode chemokine receptor-like peptides. These genes, UL33, UL78, US27, and US28, are expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7f792ae97c134a6cc48ee8cbdbbfa12
https://pubmed.ncbi.nlm.nih.gov/12224510
https://pubmed.ncbi.nlm.nih.gov/12224510
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 58(5)
In recent years, the technology of solid-phase peptide synthesis (SPPS) has improved to the extent that chemical synthesis of small proteins may be a viable complementary strategy to recombinant expression. We have prepared several modified and wild-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf7309db4df1ac67e56ea411b0f9160c
https://pubmed.ncbi.nlm.nih.gov/11892845
https://pubmed.ncbi.nlm.nih.gov/11892845
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642639746
The ubiquitous, opportunistic pathogen human cytomegalovirus (CMV) encodes several proteins homologous to those of the host organism. Four different CMV genes encode chemokine receptor-like peptides. These genes, UL33, UL78, US27, and US28, are expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b684858465b05905f230932b4661897
https://doi.org/10.1007/978-3-642-59421-2_13
https://doi.org/10.1007/978-3-642-59421-2_13
Autor:
J D, Blake, F E, Cohen
Publikováno v:
Journal of molecular biology. 307(2)
Improved sequence alignment at low pairwise identity is important for identifying potential remote homologues in database searches and for obtaining accurate alignments as a prelude to modeling structures by homology. Our work is motivated by two obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13b70f73400c8c524bee3db98749b6ab
https://pubmed.ncbi.nlm.nih.gov/11254392
https://pubmed.ncbi.nlm.nih.gov/11254392
Publikováno v:
Archives of virology. Supplementum. (16)
Variations in prions, which cause different disease phenotypes, are often referred to as strains. Strains replicate with a high degree of fidelity, which demands a mechanism that can account for this phenomenon. Prion strains differ by qualitative ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0876c6b03d81a496c2dd9fe36142e9d6
https://pubmed.ncbi.nlm.nih.gov/11214926
https://pubmed.ncbi.nlm.nih.gov/11214926
Publikováno v:
Journal of molecular biology. 299(2)
The divergent evolution of proteins in cellular signaling pathways requires ligands and their receptors to co-evolve, creating new pathways when a new receptor is activated by a new ligand. However, information about the evolution of binding specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::060a3c0a4cfbbaf269207bd208eff57a
https://pubmed.ncbi.nlm.nih.gov/10860738
https://pubmed.ncbi.nlm.nih.gov/10860738
Autor:
G L, Silverman, K, Qin, R C, Moore, Y, Yang, P, Mastrangelo, P, Tremblay, S B, Prusiner, F E, Cohen, D, Westaway
Publikováno v:
The Journal of biological chemistry. 275(35)
The Prnd gene encodes a homolog of the cellular prion protein (PrP(C)) called doppel (Dpl). Up-regulation of Prnd mRNA in two distinct lines of PrP gene ablated (Prnp(0/0)) mice, designated Rcm0 and Ngsk, is associated with death of Purkinje cells. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bffb3ab17b6ff748ffb60b457360f2b
https://pubmed.ncbi.nlm.nih.gov/10842180
https://pubmed.ncbi.nlm.nih.gov/10842180
Autor:
Z F, Kanyo, K M, Pan, R A, Williamson, D R, Burton, S B, Prusiner, R J, Fletterick, F E, Cohen
Publikováno v:
Journal of molecular biology. 293(4)
The X-ray crystallographic structures of the anti-Syrian hamster prion protein (SHaPrP) monoclonal Fab 3F4 alone, as well as the complex with its cognate peptide epitope (SHaPrP 104-113), have been determined to atomic resolution. The conformation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e55a256d8dfd0d05d6ca8bebf593915e
https://pubmed.ncbi.nlm.nih.gov/10543972
https://pubmed.ncbi.nlm.nih.gov/10543972
Publikováno v:
Journal of molecular biology. 286(2)
Prion disease is caused by the propagation of a particle containing PrPSc, a misfolded form of the normal cellular prion protein (PrPC). PrPC can re-fold to form PrPSc with loss of alpha-helical structure and formation of extensive beta-sheet structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee9c359c4df4239b3d749abea3df9e53
https://pubmed.ncbi.nlm.nih.gov/9973573
https://pubmed.ncbi.nlm.nih.gov/9973573