Zobrazeno 1 - 10
of 219
pro vyhledávání: '"F D, Boudinot"'
Publikováno v:
American Journal of Veterinary Research. 61:775-778
Objective—To determine pharmacokinetics of troglitazone in healthy cats after IV and oral administration of a single dose of the drug. Animals—5 healthy ovariohysterectomized adult cats. Procedure—Using a randomized crossover design, cats were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f223d9719590b0c11714358cafd4659
https://doi.org/10.2460/ajvr.2000.61.775
https://doi.org/10.2460/ajvr.2000.61.775
Autor:
Chung K. Chu, F. D. Boudinot, Z.-S. Xu, K. K. Manouilov, L. S. Manouilova, Raymond F. Schinazi
Publikováno v:
Antiviral Chemistry and Chemotherapy. 8:409-415
The lymphatic system is a primary target for early anti-human immunodeficiency virus drug therapy. Strategies are currently being sought to enhance the delivery of nucleoside analogues such as 3′-deoxy-2′,3′-didehydrothymidine (stavudine; d4T)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de04ccf5c211060b6295f5ca5919ee4a
https://doi.org/10.1177/095632029700800503
https://doi.org/10.1177/095632029700800503
Autor:
Harold M. McClure, Raymond F. Schinazi, K. K. Manouilov, F. D. Boudinot, Huizhong Chen, Chung K. Chu
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 691:425-432
(−)-β- d -2-Aminopurine dioxolane (APD), (−)-β- d -2-amino-6-chloropurine dioxolane (ACPD) and dioxolane guanine (DXG) are nucleoside analogues possessing potent activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250dfdaee4d7d6e75df221779be9f114
https://doi.org/10.1016/s0378-4347(96)00473-2
https://doi.org/10.1016/s0378-4347(96)00473-2
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:2332-2336
(-)-beta-D-2-Aminopurine dioxolane (APD) and (-)-beta-D-2-amino-6-chloropurine dioxolane (ACPD) are recently synthesized dioxolanylpurine nucleoside derivatives being developed as potential prodrugs for the antiviral nucleoside analog (-)-beta-D-diox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da687217dde76246e0dcf930a3f02140
https://doi.org/10.1128/aac.40.10.2332
https://doi.org/10.1128/aac.40.10.2332
Publikováno v:
Antiviral Chemistry and Chemotherapy. 7:167-172
Lipophilic prodrugs of 2′,3′-dideoxycytidine (ddC), 4,5′-diacetyI-ddC (DAC), 4,5′-ditrimethylacetyl-ddC (DTMAC), 4,5′-dicyclopentylpropionyl-ddC (DCYPP) and 5′-cholesteryl-ddC (CHOL), were evaluated for their utility in improving brain de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa0995adc1afc3c1280ec5b016f94c20
https://doi.org/10.1177/095632029600700307
https://doi.org/10.1177/095632029600700307
Autor:
Raymond F. Schinazi, Bud C. Tennant, F. D. Boudinot, Prabhu Rajagopalan, Baldwin Bh, Chung K. Chu
Publikováno v:
Antiviral Chemistry and Chemotherapy. 7:65-70
The woodchuck ( Marmota monax) is a useful animal model for evaluating the in-vivo efficacy of antiviral agents against hepatitis B viral infection (HBV). The pharmacokinetics of a newly synthesized antiviral agent (-)-β-D-2,6-diaminopurine dioxolan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e0761afbc08e5a39da3b4f4e54b48fe
https://doi.org/10.1177/095632029600700202
https://doi.org/10.1177/095632029600700202
Autor:
R. F. Schinazi, B. H. Baldwin, Chung K. Chu, B. C. Tennant, Prabhu Rajagopalan, F. D. Boudinot
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:642-645
The woodchuck (Marmota monax) has proven to be a suitable animal model for studying hepatitis B virus (HBV) infection owing to similarities in the course of infection between woodchuck hepatitis virus (WHV) in woodchucks and HBV in humans. (-)-beta-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf60bf1026d775b36bb45c8377f8c0b
https://doi.org/10.1128/aac.40.3.642
https://doi.org/10.1128/aac.40.3.642
Autor:
V R Jarugula, F. D. Boudinot
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 677:199-203
A rapid, sensitive and reproducible ion-pair, reversed-phase high-performance liquid chromatographic (HPLC) method was developed to simultaneously quantitate 5-fluorouracil (5FU) and its prodrugs, tegafur (TF) and 4-deoxy-5-fluorouracil (DFU), in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8718b33fff6f21ab102705b21fefb348
https://doi.org/10.1016/0378-4347(95)00438-6
https://doi.org/10.1016/0378-4347(95)00438-6
Autor:
J W Witcher, F. D. Boudinot
Publikováno v:
Pharmaceutical Research. 13:1720-1724
Purpose. To illustrate the application of a discontinuous oral absorption model to cimetidine and ranitidine plasma concentration versus time data to demonstrate the use of the model for drugs which display discontinuous oral absorption profiles, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80a3ad3a61d8bd1416a449a25ba06bf4
https://doi.org/10.1023/a:1016457110726
https://doi.org/10.1023/a:1016457110726
Autor:
Prabhu Rajagopalan, Harold M. McClure, Raymond F. Schinazi, Chung K. Chu, F. D. Boudinot, Zhiling Gao
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 672:119-124
(-)-beta-D-2,6-Diaminopurine dioxolane (DAPD) and its metabolite dioxolane guanosine (DXG) have potent activity against hepatitis B virus and HIV, in vitro. A reversed-phase HPLC analytical method using UV and on-line radiochemical detection for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196b50561c84081ddcb0c781c8bb1dc5
https://doi.org/10.1016/0378-4347(95)00197-q
https://doi.org/10.1016/0378-4347(95)00197-q