Výsledky vyhledávání

Tumorigenic potential of carbaryl in the heterozygous p53 knockout mouse model

Autor: N.G. Carmichael, D. Bigot-Lasserre, F Chuzel, R. Bars, E. Debruyne

Publikováno v: Food and Chemical Toxicology. 41:99-106

The heterozygous p53 knockout mouse model was used to assess whether vascular tumors noted in a 2-year carcinogenicity study in CD-1 mice with carbaryl were induced through a genotoxic mechanism. This knockout mouse model was selected for carbaryl be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127da4080b3eee534ea37cf998b317a6
https://doi.org/10.1016/s0278-6915(02)00207-7

Zobrazit plný text záznamu

The development of methods for assessing the in vivo oestrogen-like effects of xenobiotics in CD-1 mice

Autor: F. Chuzel, A.G. Smith, M.J Tucker, Z. Mehmood, N.G. Carmichael

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 38(6)

The increasing awareness and concern about the potential health risks posed to the ecosystem and to man by endocrine disrupting chemicals with oestrogen-like activity in the environment has focused attention on the need for developing sensitive and s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f270b543c9c4834eec1add4bac28c1
https://pubmed.ncbi.nlm.nih.gov/10828501

Zobrazit plný text záznamu

Stimulating effect of both human recombinant inhibin A and activin A on immature porcine Leydig cell functions in vitro

Autor: H, Lejeune, F, Chuzel, P, Sanchez, P, Durand, J P, Mather, J M, Saez

Publikováno v: Endocrinology. 138(11)

In addition to the regulation of FSH secretion, it has been clearly shown that inhibin and activin have paracrine/autocrine effects in the gonads. We have studied the effect of human recombinant inhibin A and human recombinant activin A on immature p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8fbde1ecbda3d31ed0002900db917972
https://pubmed.ncbi.nlm.nih.gov/9348206

Zobrazit plný text záznamu

Regulation of intestinal cholecystokinin gene expression by glucocorticoids

Autor: Jean-Claude Cuber, F. Chuzel, Jean-Alain Chayvialle, M. Blanc, M. Cordier-Bussat, C. Bernard, Christelle Ratineau, C. Roche

Publikováno v: Journal of Endocrinology
Journal of Endocrinology, BioScientifica, 1996, 151, pp.137-145

The effect of glucocorticoids on the expression of intestinal cholecystokinin (CCK) was investigated both in vivo and in cell culture systems. In vivo, 2-day administration of methylprednisolone to adult male rats induced a decrease in CCK-like immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146dae2ee20d3e5a90bdd1f0dc35c434
https://pubmed.ncbi.nlm.nih.gov/8943778

Zobrazit plný text záznamu

Regulation by gonadotropins of the messenger ribonucleic acid for P450 side-chain cleavage, P450(17) alpha-hydroxylase/C17,20-lyase, and 3 beta-hydroxysteroid dehydrogenase in cultured pig Leydig cells

Autor: A M, Clark, F, Chuzel, P, Sanchez, J M, Saez

Publikováno v: Biology of reproduction. 55(2)

The Leydig cell from the immature pig provides a good model for studying testicular steroidogenesis. Regulation of the enzymes involved, which has been well studied in rodents, has not been characterized in the pig. The objectives of this study were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69bbbe3114498f88fdc054337b12cd4d
https://pubmed.ncbi.nlm.nih.gov/8828839

Zobrazit plný text záznamu

[Paracrine regulation of Leydig cells]

Autor: H, Lejeune, F, Chuzel, T, Thomas, O, Avallet, R, Habert, P, Durand, J, Saez

Publikováno v: Annales d'endocrinologie. 57(1)

In addition to the endocrine control of Leydig cell functions by LH, paracrine control of Leydig cell functions has been suspected from the indirect stimulatory effect of FSH on Leydig cells. Coculture experiments of Leydig and Sertoli cells and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9725c406b592daaa008915dd4d22972
https://pubmed.ncbi.nlm.nih.gov/8734290

Zobrazit plný text záznamu

Induction by LH/hCG of an increase in the rate of pig Leydig cell receptor mRNA degradation

Autor: M. Vigier, O. Avallet, H. Schteingart, J. M. Saez, F. Chuzel

Publikováno v: Function of somatic cells in the testis
Function of somatic cells in the testis, Springer Verlag, 1994
Function of Somatic Cells in the Testis ISBN: 9781461276197

Luteinizing hormone (LH) is absolutely required for the maintenance of Leydig cell-specific functions, and this hormone is the main factor that under physiological conditions controls Leydig cell testosterone (T) secretion. It is clear that the abili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38fd2164e64b28c1b0470bbb4a6efbc
https://hal.inrae.fr/hal-02843771