Characteristics of the population with mild COVID-19 symptoms eligible for early treatment attended in a single center in Northern Italy

Autor: Paola Magro, M. Degli Antoni, B. Formenti, F. Viola, F. Castelli, S. Amadasi, E. Quiros-Roldan

Publikováno v: Journal of Infection and Public Health, Vol 16, Iss 1, Pp 104-106 (2023)

After more than two years from the first COVID-19 detected case in Brescia, Northern Italy, monoclonal antibodies and antiviral therapy aimed at early treatment of mild COVID-19 in patients at risk of progression and of hospitalization has been appro

Externí odkaz: https://doaj.org/article/c358985dc35548ce97c19b87474c608a

Simultaneous assimilation of water levels from river gauges and satellite flood maps for near-real-time flood mapping

Autor: A. Annis, F. Nardi, F. Castelli

Publikováno v: Hydrology and Earth System Sciences, Vol 26, Pp 1019-1041 (2022)

Hydro-meteo hazard early warning systems (EWSs) are operating in many regions of the world to mitigate nuisance effects of floods. EWS performances are majorly impacted by the computational burden and complexity affecting flood prediction tools, espe

Externí odkaz: https://doaj.org/article/4ba59815a731468a88422c30f04e5bc8

Screening of the Pandemic Response Box Reveals an Association between Antifungal Effects of MMV1593537 and the Cell Wall of Cryptococcus neoformans, Cryptococcus deuterogattii, and Candida auris

Autor: Haroldo C. de Oliveira, Rafael F. Castelli, Flavia C. G. Reis, Kirandeep Samby, Joshua D. Nosanchuk, Lysangela R. Alves, Marcio L. Rodrigues

Publikováno v: Microbiology Spectrum, Vol 10, Iss 3 (2022)

ABSTRACT There is an urgent unmet need for novel antifungals. In this study, we searched for novel antifungal activities in the Pandemic Response Box, a collection of 400 structurally diverse compounds in various phases of drug discovery. We identifi

Externí odkaz: https://doaj.org/article/587ddf021ead413daf2ba570cf83f622

Multi-Criteria Decision Analysis to prioritize hospital admission of patients affected by COVID-19 in low-resource settings with hospital-bed shortage

Autor: Pasquale De Nardo, Elisa Gentilotti, Fulvia Mazzaferri, Eleonora Cremonini, Paul Hansen, Herman Goossens, Evelina Tacconelli, E. Durante Mangoni, L.L. Florio, R. Zampino, F. Mele, I. Gentile, B. Pinchera, N. Coppola, M. Pisaturo, R. Luzzati, N. Petrosillo, E. Nicastri, A. Corpolongo, M.A. Cataldo, A. D’Abramo, G. Maffongelli, L. Scorzolini, C. Palazzolo, E. Boumis, A. Pan, A. D’Arminio Monforte, F. Bai, S. Antinori, F.G. De Rosa, S. Corcione, T. Lupia, S.M. Pinna, S. Scabini, F. Canta, S. Belloro, Z. Bisoffi, A. Angheben, F. Gobbi, E. Turcato, N. Ronzoni, L. Moro, S. Calabria, P. Rodari, G. Bertoli, G. Marasca, M. Puoti, A. Gori, A. Bandera, D. Mangioni, M. Rizzi, F. Castelli, A. Montineri, C.A. Coco, M. Maresca, M. Frasca, D. Aquilini, M. Vincenzi, L. Lambertenghi, M.E. De Rui, E. Razzaboni, P. Cattaneo, A. Visentin, A. Erbogasto, I. Dalla Vecchia, I. Coledan, M. Vecchi, G. Be, L. Motta, A. Zaffagnini, N. Auerbach, P. Del Bravo, A.M. Azzini, E. Righi, E. Carrara, A. Savoldi, M. Sibani, E. Lattuada, G. Carolo, M. Cordioli, F. Soldani, M.D. Pezzani, S. Avallone, R. Bruno, A. Ricciardi, M.P. Saggese, G. Malerba

Publikováno v: International Journal of Infectious Diseases, Vol 98, Iss , Pp 494-500 (2020)

Objective: To use Multi-Criteria Decision Analysis (MCDA) to determine weights for eleven criteria in order to prioritize COVID-19 non-critical patients for admission to hospital in healthcare settings with limited resources. Methods: The MCDA was ap

Externí odkaz: https://doaj.org/article/242ab2e53b66490485d7cddaf276a420

Analysis of Cryptococcal Extracellular Vesicles: Experimental Approaches for Studying Their Diversity Among Multiple Isolates, Kinetics of Production, Methods of Separation, and Detection in Cultures of Titan Cells

Autor: Flavia C. G. Reis, Bianca Gimenez, Luísa J. Jozefowicz, Rafael F. Castelli, Sharon T. Martins, Lysangela R. Alves, Haroldo C. de Oliveira, Marcio L. Rodrigues

Publikováno v: Microbiology Spectrum, Vol 9, Iss 1 (2021)

ABSTRACT Extracellular vesicles (EVs) produced by members of the Cryptococcus genus are associated with fundamental processes of fungal physiology and virulence. However, several questions about the properties of cryptococcal EVs remain unanswered, m

Externí odkaz: https://doaj.org/article/03cc3035da81490f8424e48bff9f8ca2