Výsledky vyhledávání

Use of a biological extract of Serratia marcescens to decrease doxorubicin-induced myelosuppression in dogs

Autor: G K, Ogilvie, R E, Elmslie, M, Cecchini, L M, Walters, F C, Pearson

Publikováno v: American journal of veterinary research. 53(10)

Fifteen dogs were given doxorubicin, IV, at a dosage of 30 mg/m2 of body surface. A commercially available biological extract of Serratia marcescens (BESM) was administered SC to 9 of these dogs (0.04 mg/kg of body weight every third day, n = 2; 0.08

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d820b98e122fc9cd7adbc12951f972aa
https://pubmed.ncbi.nlm.nih.gov/1280926

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Protection from chemotherapy-induced neutropenia by ImuVert

Autor: F C Pearson, M Hindahl, Joaquin J. Jimenez, H S Huang, Adel A. Yunis

Publikováno v: The American journal of the medical sciences. 303(2)

Neutropenia is a major cause of chemotherapy-induced morbidity. This study examines the effect of ImuVert on the course of neutropenia from Cytoxan and Adriamycin. In adult rats treated with either Cytoxan or Adriamycin and ImuVert, the absolute neut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7aaebe730968ad3ed09d39e6955c5d
https://pubmed.ncbi.nlm.nih.gov/1539614

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Evaluation of a biologic response modifier derived from Serratia marcescens: effects on feline macrophages and usefulness for the prevention and treatment of viremia in feline leukemia virus-infected cats

Autor: R E, Elmslie, G K, Ogilvie, S W, Dow, P, Gasper, E A, Hoover, M F, Cooper, F C, Pearson

Publikováno v: Molecular biotherapy. 3(4)

Normal feline bone marrow-derived macrophages released maximum concentrations of interleukin-6, tumor necrosis factor, and interleukin-1 when stimulated with ImuVert (Cell Technology Inc, Boulder, CO, USA) at dosages of 1.0 microgram/ml, 5.0 microgra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::65bed7c6195876341af5657dde193794
https://pubmed.ncbi.nlm.nih.gov/1768375

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Selective potentiation of host resistance in mice following treatment with Pyrexol

Autor: R V, House, F C, Pearson, P T, Thomas

Publikováno v: Molecular biotherapy. 2(3)

The purpose of this study was to examine the effect of treatment with the biologic response modifier Pyrexol on murine host resistance to various infectious organisms. Adult female CD1 mice were treated with a single subcutaneous 100-micrograms injec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0072db4b2a5ec0400498f1976bf12453
https://pubmed.ncbi.nlm.nih.gov/2171562

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Establishment of beta-hydroxy fatty acids as chemical marker molecules for bacterial endotoxin by gas chromatography-mass spectrometry

Autor: S K Maitra, R Nachum, F C Pearson

Publikováno v: Applied and Environmental Microbiology. 52:510-514

Selected ion-monitoring gas chromatography-mass spectrometry was used for detection of beta-hydroxy fatty acids as an independent assay for the presence or absence of endotoxin in materials claimed to induce nonspecific activation of Limulus amoebocy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414473f6befee1fc6ff947dd7eefe9bf
https://doi.org/10.1128/aem.52.3.510-514.1986

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Relative potencies of four reference endotoxin standards as measured by the Limulus amoebocyte lysate and USP rabbit pyrogen tests

Autor: F C Pearson, G Donohue, K Story, M. Weary

Publikováno v: Applied and Environmental Microbiology. 40:1148-1151

Four commonly used reference endotoxin standards, Escherichia coli O113:H10:K0, E. coli O55:B5, Salmonella abortusequi, and Shigella dysenteriae were compared by the USP rabbit pyrogen and the Limulus amoebocyte lysate tests. By the rabbit pyrogen te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8993a16f26ae95853ee3866b14bf2cb5
https://doi.org/10.1128/aem.40.6.1148-1151.1980

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Influence of fine structure of lipid A on Limulus amebocyte lysate clotting and toxic activities

Autor: Edgar Ribi, Nilofer Qureshi, F C Pearson, Jon E. Peterson, A G Johnson, J Wiggins, Kuni Takayama, John Leonard Cantrell, Christian R. H. Raetz

Publikováno v: Infection and Immunity. 45:350-355

We examined the relationship between the fine structure of lipid A and the toxicity of endotoxin or lipopolysaccharides as measured by the Limulus amebocyte lysate (LAL), rabbit pyrogenicity, chicken embryo lethal dose, and dermal Shwartzman reaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf54e4843cdbd08c9ec52e360f0942c
https://doi.org/10.1128/iai.45.2.350-355.1984

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Comparison of several control standard endotoxins to the National Reference Standard Endotoxin--an HIMA collaborative study

Autor: J F Cooper, G Lindsay, R N Berzofsky, J D Wilson, H E Sargent, M E Weary, Amy L. Lane, T J Novitsky, F C Pearson, H Lin

Publikováno v: Applied and Environmental Microbiology. 50:91-93

A collaborative study, initiated under the auspices of the Health Industry Manufacturers Association (HIMA), was designed to establish the relationship of Escherichia coli O55:B5 endotoxin (the control standard endotoxin of HIMA and the Food and Drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99abda0123ce548589a6c7750db54ce5
https://doi.org/10.1128/aem.50.1.91-93.1985

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