Zobrazeno 1 - 10
of 86
pro vyhledávání: '"F C, Arnett"'
Publikováno v:
International Journal of Immunopathology and Pharmacology. 24:595-601
Transgenic mice that over-express connective tissue growth factor (CTGF) in fibroblasts under the control of an enhancer/promoter element of the Col1a2 gene ( Col1a2-CTGF) recapitulate multiorgan fibrosis similar to fibrosis observed in Scleroderma (
Publikováno v:
The Journal of Immunology. 152:4192-4202
The human Ro ribonucleoprotein is a clinically important yet poorly understood autoantigen. The contribution of Ro autoantibodies to pathogenesis of autoimmune disease remains unclear, as do the stimuli that initiate and maintain the response. Recent
Publikováno v:
Arthritis and Rheumatism, 60, 12, pp. 3815-20
Arthritis and Rheumatism, 60, 3815-20
Arthritis and Rheumatism, 60, 3815-20
Contains fulltext : 81350.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To investigate the possible role of the FAS -670A>G functional polymorphism in the genetic predisposition to systemic sclerosis (SSc) susceptibility or clinical phenoty
Publikováno v:
The Journal of Immunology. 146:3871-3876
In order to define the HLA-DR and DQ alleles, as well as the specific DQA1 and DQB1 chain genes involved in the anti-Ro/La autoantibody responses, RFLP analysis and sequence-specific oligonucleotide typing was carried out on 58 Caucasians and 48 Amer
Autor:
D. Andrade, L. Seguro, A. Ribeiro, J. Moraes, C. Saad, N. Aikawa, A. Calich, V. Viana, S. Pasoto, M. Levy-Neto, I. Laurindo, M. Timenestsky, A. Precioso, E. Bonfa, P. Sampaio-Barros, J. C. Wang, S. Assassi, G. Guo, W. Z. Tu, F. K. Tan, M. D. Mayes, J. D. Reveille, W. Y. Wu, H. J. Zou, Y. Q. Zhao, H. Y. Chu, J. Liu, X. D. Zhou, P. Dieude, M. Bouaziz, G. Riemekasten, P. Airo, M. Muller, D. Cusi, G. Chiocchia, C. Boileau, Y. Allanore, F. Carmona, R. Gutala, C. P. Simeon, P. Carreira, N. Ortego Centeno, E. Vicente Rabaneda, F. J. Garcia Hernandez, P. Garcia De La Pena, M. Fernandez Castro, L. Martinez Estupinan, M. V. Egurbide, B. P. Tsao, P. Gourh, S. K. Agarwal, F. C. Arnett, J. Martin
Publikováno v:
Rheumatology. 51:ii23-ii24
Publikováno v:
Arthritis and rheumatism. 44(8)
To determine if there are abnormalities in fibrillin 1-containing microfibrils in the extracellular matrix (ECM) of primary dermal fibroblasts explanted from patients with systemic sclerosis (SSc).Explanted fibroblasts from unaffected skin of 12 SSc
Publikováno v:
Arthritis and rheumatism. 44(6)
To determine the frequency with which scleroderma (systemic sclerosis; SSc) recurs in families and the familial relative risk (lambda) in the US.Family histories of SSc were prospectively surveyed in 3 large US cohorts of SSc patients, 2 in Texas and
Publikováno v:
Arthritis and rheumatism. 44(4)
Previously, we demonstrated with the use of microsatellite markers that a 2-cM haplotype on chromosome 15q containing the fibrillin 1 gene (FBN1) was strongly associated with systemic sclerosis (SSc) in the Choctaw, a population with high SSc prevale
Autor:
T, Witte, T, Matthias, F C, Arnett, H H, Peter, K, Hartung, C, Sachse, R, Wigand, A, Braner, J R, Kalden, H J, Lakomek, R E, Schmidt
Publikováno v:
The Journal of rheumatology. 27(11)
To determine the prevalence of IgA and IgG autoantibodies against alpha-fodrin in patients with primary and secondary Sjögren's syndrome (SS) and controls.An ELISA detecting IgA and IgG antibodies against alpha-fodrin was developed. We examined the
Publikováno v:
Arthritis and rheumatism. 43(11)
We previously reported the presence of autoantibodies to the extracellular matrix protein, fibrillin 1, in sera from patients with systemic sclerosis (SSc). These autoantibodies appeared to be highly disease-specific but had significantly different f