Zobrazeno 1 - 10
of 69
pro vyhledávání: '"F Bostick-Bruton"'
Publikováno v:
Journal of Clinical Investigation. 87:772-777
Studies were undertaken to investigate acquired resistance to cisplatin in human ovarian cancer cells. The cell lines A2780 and A2780/CP70 were studied to assess their respective characteristics of drug accumulation and efflux, cytosolic inactivation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a592727ee44615d413fb22584c99a0
https://doi.org/10.1172/jci115080
https://doi.org/10.1172/jci115080
Autor:
E C, Kohn, E, Reed, G A, Sarosy, L, Minasian, K S, Bauer, F, Bostick-Bruton, V, Kulpa, E, Fuse, A, Tompkins, M, Noone, B, Goldspiel, J, Pluda, W D, Figg, L A, Liotta
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(6)
Preclinical and clinical investigation of the combination of the antiangiogenesis/anti-invasion agent carboxyamido-triazole (CAI) administered with the cytotoxic agent paclitaxel (PAX).Colony-forming assays were used to test the activity of CAI plus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49533a657dacaa4ae9c7719414c67d93
https://pubmed.ncbi.nlm.nih.gov/11410496
https://pubmed.ncbi.nlm.nih.gov/11410496
Publikováno v:
Anticancer research. 20(2A)
Nucleotide excision repair (NER) is responsible for the repair of platinum-DNA lesions. ERCC-1 is a critical gene within the NER pathway, and cells without a functional ERCC-1 do not repair cisplatin-caused DNA damage. The present study was therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dd10d2c69c0c9d94f06c477ca841158
https://pubmed.ncbi.nlm.nih.gov/10810335
https://pubmed.ncbi.nlm.nih.gov/10810335
Publikováno v:
Anticancer research. 18(4A)
Enhanced expression of the human excision repair enzyme ERCC-1 is associated with cellular and clinical resistance to cisplatin in human ovarian cancer. High levels of expression of ERCC-1 appear to be associated with increased activity of the nucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3587a86925441dffb6627131503b106c
https://pubmed.ncbi.nlm.nih.gov/9703867
https://pubmed.ncbi.nlm.nih.gov/9703867
Autor:
M D, Dabholkar, M S, Berger, J A, Vionnet, L, Overton, C, Thompson, F, Bostick-Bruton, J J, Yu, J R, Silber, E, Reed
Publikováno v:
Molecular carcinogenesis. 17(1)
Nucleotide excision repair (NER) is an ordered process in nonmalignant cells, in both human and nonhuman systems. We previously reported that in human brain there is discordant mRNA expression of excision repair cross-complementing (ERCC) 1 and ERCC2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc42c118a14a1090b511c3b6e46528c8
https://pubmed.ncbi.nlm.nih.gov/8876669
https://pubmed.ncbi.nlm.nih.gov/8876669
Autor:
E, Reed, R J, Parker, I, Gill, A, Bicher, M, Dabholkar, J A, Vionnet, F, Bostick-Bruton, R, Tarone, F M, Muggia
Publikováno v:
Cancer research. 53(16)
Using atomic absorbance spectrometry with Zeeman background correction, we measured platinum-DNA adduct levels in leukocyte DNA of 49 patients receiving therapy consisting of only carboplatin and cisplatin. Twenty-four histological types of malignanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48d2dd4b0bb7762e6a25cb3acd6dc5e0
https://pubmed.ncbi.nlm.nih.gov/8339278
https://pubmed.ncbi.nlm.nih.gov/8339278
Publikováno v:
Cancer research. 53(2)
The human ovarian cancer cell lines A2780 and A2780/CP70 were studied to investigate the cellular basis for their relative sensitivities to tetrachloro(DL-trans)-1,2-diamminecyclohexaneplatinum(IV) (ormaplatin). Cells were exposed to ormaplatin for 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5c58a853730160ea9a56bc98b299185
https://pubmed.ncbi.nlm.nih.gov/8417816
https://pubmed.ncbi.nlm.nih.gov/8417816
Publikováno v:
Journal of the National Cancer Institute. Monographs. (15)
Taxol and cisplatin are the two most effective agents discovered to date for treating advanced-stage cancer of the ovary. Learning how best to combine these agents is the focus of preclinical and clinical studies conducted at a number of institutions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa66fee5a1f47071907d23602354badb
https://pubmed.ncbi.nlm.nih.gov/7912534
https://pubmed.ncbi.nlm.nih.gov/7912534
Publikováno v:
The Journal of Immunology. 130:2666-2670
Neoplastic cells obtained from the pleural effusion of a patient with Hodgkin's disease have been maintained in culture since 1978. These tumor cells have been shown to have the cytologic features, cytochemical staining, and cell surface markers of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dca2bfaa4d6fc6b0f21fa95e42bea3f
https://doi.org/10.4049/jimmunol.130.6.2666
https://doi.org/10.4049/jimmunol.130.6.2666
Publikováno v:
The Journal of Immunology. 132:2672-2677
Purified human peripheral blood T cells that have been depleted of Ia-bearing cells and adherent cells do not proliferate in response to concanavalin A. The addition of as few as 1% radiated L428 tumor cells restores the proliferative capacity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7daa7ca1bb32485679c83b94cf08175
https://doi.org/10.4049/jimmunol.132.5.2672
https://doi.org/10.4049/jimmunol.132.5.2672