Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

DOP33 Single-cell analysis identifies pathological fibroblasts as a new therapeutic target to prevent intestinal fibrosis in Crohn’s disease

Autor: B J Ke, S Abdurahiman, F Biscu, S Verstockt, B Verstockt, G de Hertogh, S Vermeire, G Matteoli

Publikováno v: Journal of Crohn's and Colitis. 17:i96-i97

Background Recurrent episodes of intestinal inflammation and tissue remodeling progressively result in fibro-stenosis and bowel obstruction in Crohn’s disease (CD). This irreversible end-stage complication is the main indication for surgical interv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc735c4a3d5f65cd27ee10de01f91fc6
https://doi.org/10.1093/ecco-jcc/jjac190.0073

The Impact of PAD4-dependent Neutrophil Extracellular Trap Formation on the Early Development of Intestinal Fibrosis in Crohn's Disease.

Autor: Dragoni G; IBD Leuven, Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism, Leuven, Belgium.; Gastroenterology Research Unit, Department of Experimental and Clinical Biochemical Sciences 'Mario Serio', University of Florence, Florence, Italy.; IBD Referral Center, Department of Gastroenterology, Careggi University Hospital, Florence, Italy., Ke BJ; Laboratory for Mucosal Immunology, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium., Picariello L; Gastroenterology Research Unit, Department of Experimental and Clinical Biochemical Sciences 'Mario Serio', University of Florence, Florence, Italy., Abdurahiman S; Laboratory for Mucosal Immunology, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium., Ceni E; Gastroenterology Research Unit, Department of Experimental and Clinical Biochemical Sciences 'Mario Serio', University of Florence, Florence, Italy., Biscu F; Laboratory for Mucosal Immunology, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.; Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom., Mello T; Gastroenterology Research Unit, Department of Experimental and Clinical Biochemical Sciences 'Mario Serio', University of Florence, Florence, Italy., Polvani S; Gastroenterology Research Unit, Department of Experimental and Clinical Biochemical Sciences 'Mario Serio', University of Florence, Florence, Italy., Innocenti T; IBD Leuven, Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism, Leuven, Belgium.; Gastroenterology Research Unit, Department of Experimental and Clinical Biochemical Sciences 'Mario Serio', University of Florence, Florence, Italy.; IBD Referral Center, Department of Gastroenterology, Careggi University Hospital, Florence, Italy., Spalart V; Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium., Milani S; Gastroenterology Research Unit, Department of Experimental and Clinical Biochemical Sciences 'Mario Serio', University of Florence, Florence, Italy.; IBD Referral Center, Department of Gastroenterology, Careggi University Hospital, Florence, Italy., D'Hoore A; Department of Abdominal Surgery, University Hospitals Leuven, KU Leuven, Leuven, Belgium., Bislenghi G; Department of Abdominal Surgery, University Hospitals Leuven, KU Leuven, Leuven, Belgium., Scaringi S; Department of Experimental and Clinical Medicine, University of Florence, 50134 Florence, Italy., Verstockt B; IBD Leuven, Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism, Leuven, Belgium.; University Hospitals Leuven, Department of Gastroenterology and Hepatology, KU Leuven, Leuven, Belgium., De Hertogh G; Laboratory of Translational Cell and Tissue Research, Department of Imaging and Pathology, Faculty of Medicine, KU Leuven, Belgium., Martinod K; Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium., Galli A; Gastroenterology Research Unit, Department of Experimental and Clinical Biochemical Sciences 'Mario Serio', University of Florence, Florence, Italy.; IBD Referral Center, Department of Gastroenterology, Careggi University Hospital, Florence, Italy., Matteoli G; Laboratory for Mucosal Immunology, Translational Research Center for Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium., Vermeire S; IBD Leuven, Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism, Leuven, Belgium.; University Hospitals Leuven, Department of Gastroenterology and Hepatology, KU Leuven, Leuven, Belgium.

Publikováno v: Journal of Crohn's & colitis [J Crohns Colitis] 2024 Aug 10. Date of Electronic Publication: 2024 Aug 10.