Zobrazeno 1 - 10 of 96 pro vyhledávání: '"F A Khaliullin"'
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Akademický článek
The screening of the compounds with antiaggregation and proaggregation activity among xantine
Autor: F Сh Kamilov, G A Timirkhanova, А V Samorodov, F A Khaliullin, R A Gubaeva
Publikováno v: RUDN Journal of Medicine, Vol 0, Iss 1, Pp 66-69 (2011)
Biological activity of first synthesized 8 xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. Obtained active derivates prove the perspectives of further investigations of bioactive su
Externí odkaz: https://doaj.org/article/bd6059dddabd4d4ca19a8c035427d8a6
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5
Synthesis and Antiplatelet and Anticoagulant Activity of Thietane-Containing 2-(5-Bromo-2,4-Dihydro-3-Oxo-1,2,4-Triazolyl-4)Acetate Salts
Autor: E. E. Klen, A. V. Samorodov, G. A. Rozit, F. A. Khaliullin, Konstantin G. Gurevich, A. L. Urakov
Publikováno v: Pharmaceutical Chemistry Journal
Sulfone II was synthesized via oxidation of ethyl 2-[5-bromo-2,4-dihydro-3-oxo-2-(thietanyl-3)-1,2,4-triazolyl- 4]acetate (I) by H2O2. Hydrolysis of esters I and II synthesized 2-[5-bromo-2,4-dihydro- 3-oxo-2-(thietanyl-3)-1,2,4-triazolyl-4]- and 2-[
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926cba1af79d7805221212f817fa74a9
https://doi.org/10.1007/s11094-021-02437-6
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6
Quantitative Determination of Angipur Drug Substance in Blood Plasma by HPLC with Fluorescence Detection
Autor: L. A. Smirnova, Alexander A. Spasov, A. F. Kucheryavenko, O. K. Abramov, A. F. Ryabukha, F. A. Khaliullin
Publikováno v: Pharmaceutical Chemistry Journal. 55:202-205
A quantitative determination method using HPLC with fluorescence detection for the xanthine derivative 3-methyl-8-(piperazin-1-yl)-7-(thietan-3-yl)-1-ethyl-1H-purine-2,6(3H,7H)-dione hydrochloride (Angipur drug substance) in donor blood plasma was de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::756c4c473c9f7aa63bb979e4f4ec3c20
https://doi.org/10.1007/s11094-021-02381-5
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7
Synthesis and Antidepressant Activity of 4-Alkyl-5-Bromo-2,4-Dihydro-2-(Thietan-3-YL)-1,2,4-Triazol-3-Ones
Autor: I. L. Nikitina, F. A. Khaliullin, N. N. Makarova, A. F. Miftakhova, E. E. Klen, A. G. Gilmanova, R. A. Gabidullin
Publikováno v: Pharmaceutical Chemistry Journal. 55:123-129
A series of 4-alkyl-5-bromo-2,4-dihydro-2-(thietan-3-yl)-1,2,4-triazol-3-ones (IIa-g) were synthesized by reacting 5-bromo-2,4-dihydro-2-(thietan-3-yl)-1,2,4-triazol-3-one (I) with alkyl halides and dimethyl sulfate. The structures of the synthesized
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c101f3843721ab71c71a84d678412aef
https://doi.org/10.1007/s11094-021-02394-0
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9
Synthesis, Antiaggregant, and Antioxidant Activity of 2-{[1-iso-butyl-3-methyl-7-(thietanyl-3)xanthin-8-yl]thio}acetic Acid Salts
Autor: L. I. Bashirova, Zh. K. Mamatov, G. A. Timirkhanova, F. A. Khaliullin, A. V. Samorodov
Publikováno v: Pharmaceutical Chemistry Journal. 54:891-896
8-Bromo-1-iso-butyl-3-methyl-7-(thietanyl-3)xanthine (II) was synthesized by alkylation of 8-bromo-3-methyl-7-(thietanyl-3)xanthine (I) with isobutyl bromide. Nucleophilic substitution of II with thioglycolic acid gave 2{[1-iso-butyl-3-methyl-7-(thie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebc1a872a6bc662acce8aa31fdb4a9d5
https://doi.org/10.1007/s11094-020-02293-w
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10
Thietanyl Protection in the Synthesis of 8-Substituted 1-Benzyl-3-methyl-3,7-dihydro- 1H-purine-2,6-diones
Autor: F. A. Khaliullin, Yuliya Shabalina
Publikováno v: Current Organic Synthesis. 17:535-539
Aim and Objective: 1-Аlkyl-3,7-dihydro-1H-purine-2,6-diones containing no substituents in the N7 position can be synthesized only using protecting groups, for example, benzyl protection. However, in the case of synthesis of 1-benzyl-3,7-dihydro-1H-p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320a68a426c11c68355d8e7628d91ca6
https://doi.org/10.2174/1570179417666200628015511
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