Zobrazeno 1 - 3
of 3
pro vyhledávání: '"F A, Sløk"'
Autor:
Apirat Chaikuad, A. E. Pedersen, F. A. Sløk, Stefan Knapp, L. K. Petersen, N. J. V. Hansen, A. B. Christensen, P. Blakskjær, M. Kořínek, J. Dietvorst, J. Holmkvist, Sandra Röhm, L. K. Larsen
Publikováno v:
MedChemComm. 7:1332-1339
A highly specific and potent (7 nM cellular IC50) inhibitor of p38α kinase was identified directly from a 12.6 million membered DNA-encoded small molecule library. This was achieved using the high fidelity yoctoReactor technology (yR) for preparing
Autor:
T N, Johansen, T B, Stensbøl, B, Nielsen, S B, Vogensen, K, Frydenvang, F A, Sløk, H, Bräüner-Osborne, U, Madsen, P, Krogsgaard-Larsen
Publikováno v:
Chirality. 13(9)
We have previously described (RS)-2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA) as a potent agonist at the (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor subtype of (S)-glutamic acid (Glu) receptors.
Autor:
T B, Stensbøl, F A, Sløk, J, Trometer, S, Hurt, B, Ebert, C, Kjøller, J, Egebjerg, U, Madsen, N H, Diemer, P, Krogsgaard-Larsen
Publikováno v:
European journal of pharmacology. 373(2-3)
(RS)-2-Amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA), which is a potent and selective agonist at (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptors, has previously been shown to desensitize AMPA receptors