Zobrazeno 1 - 10
of 38
pro vyhledávání: '"F A, Ofosu"'
Autor:
Yaw Serfor-Armah, F. G. Ofosu, O. Gyampo, H. Ahiamadjie, Dennis K. Adotey, J. B. Tandoh, Benjamin J.B. Nyarko, Samuel B. Dampare
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 288:653-661
Most studies in gold mining areas in Ghana have been concentrated on soil, sediment and atmospheric pollution, very limited work has been conducted on consumed crops. This work therefore aims at shedding more light on the effects of gold mining activ
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 18
Development of factor VIII (FVIII) inhibitors is the most severe and challenging complication of haemophilia A treatment and represents the highest economic burden for a chronic disease. Therefore, major research efforts are ongoing to optimize the t
Publikováno v:
Blood. 77:2185-2189
Antithrombin-III-Hamilton has been shown to be a structural variant of antithrombin-III (AT-III) with normal heparin affinity but impaired protease inhibitory activity. The molecular defect of AT-III-Hamilton is the substitution of Thr for Ala at ami
The blood platelet as a model for regulating blood coagulation on cell surfaces and its consequences
Autor:
F A, Ofosu
Publikováno v:
Biochemistry. Biokhimiia. 67(1)
Platelets actively participate in regulating thrombin production following physical or chemical injury to blood vessels. Injury to blood vessels initiates activation of the large numbers of platelets that appear in the subendothelium where they becom
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 7(2)
This study reports the generation of an immunodeficient murine model for haemophilia B, obtained by breeding factor IX-deficient mice with an immunodeficient mouse strain, and use of this mouse model to evaluate the long-term efficacy and safety of a
Autor:
M I, Furman, P, Nurden, M C, Berndt, A T, Nurden, S E, Benoit, M R, Barnard, F A, Ofosu, A D, Michelson
Publikováno v:
Thrombosis and haemostasis. 84(5)
The only known function of the 41 amino acid cleaved peptide (TR1-41) of the seven transmembrane domain thrombin receptor (PARI) is to activate platelets (as determined by aggregation, surface P-selectin, and fibrinogen binding to activated GPIIb-III
Autor:
F A, Ofosu, K A, Nyarko
Publikováno v:
Hematology/oncology clinics of North America. 14(5)
Platelets are essential participants in hemostasis and thrombosis. Platelets normally circulate in blood as discoid resting cells that become critical constituents of hemostatic plugs or arterial thrombi only after specific receptors on platelet memb
Publikováno v:
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 6(1)
Publikováno v:
Blood. 91(1)
We have previously described a kindred with factor VII (FVII) deficiency whose members exhibited reduced procoagulant activity relative to FVII antigen concentration. In this report, the molecular genetic basis of the FVII defect has been determined
Publikováno v:
Blood. 87(12)
A potentially cost-effective strategy for gene therapy of hemophilia B is to create universal factor IX-secreting cell lines suitable for implantation into different patients. To avoid graft rejection, the implanted cells are enclosed in alginate-pol