Copper and gas-phase cigarette smoke inhibit plasma lecithin:cholesterol acyltransferase activity by different mechanisms.

Autor: J K Bielicki, M R McCall, J J van den Berg, F A Kuypers, T M Forte

Publikováno v: Journal of Lipid Research, Vol 36, Iss 2, Pp 322-331 (1995)

Cigarette smokers have reduced levels of plasma high density lipoprotein (HDL) compared to nonsmokers and are at risk of premature cardiovascular disease. Previous work from this laboratory has shown that exposure of human plasma to gas-phase cigaret

Externí odkaz: https://doaj.org/article/0268688121d04c8598d65cc53252845b

Biomarkers to Differentiate Acute Chest Syndrome From Vaso-Occlusive Crisis in Children With Sickle Cell Disease.

Autor: Wang K; Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Olave N; Department of Pediatrics, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Aggarwal S; Department of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida, USA., Oh JY; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Patel RP; Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Rahman AKMF; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama, USA., Lebensburger J; Department of Pediatrics, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA., Alishlash AS; Department of Pediatrics, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Publikováno v: European journal of haematology [Eur J Haematol] 2024 Nov 05. Date of Electronic Publication: 2024 Nov 05.

Hemoglobin Hakkari: an autosomal dominant form of beta thalassemia with inclusion bodies arising from de novo mutation in exon 2 of beta globin gene

Autor: B, Kanathezhath, F K, Hazard, H, Guo, J, Kidd, M, Azimi, F A, Kuypers, E P, Vichinsky, A, Lal

Publikováno v: Pediatric bloodcancer. 54(2)

Certain beta globin gene mutations produce a thalassemia major phenotype in the heterozygous state. While most such patients have thalassemia intermedia, we describe a young Guatemalan child with a de novo mutation in the beta globin gene, codon 31 T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fe393339b5577d159c056ba52768a7cd
https://pubmed.ncbi.nlm.nih.gov/19852066

The role of secretory phospholipase A2 in acute chest syndrome

Autor: F A, Kuypers, L A, Styles

Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 50(1)

Acute chest syndrome (ACS) is the leading cause of death in sickle cell disease. Severe ACS often develops in the course of a vasoocclusive crisis (VOC), and frequently involves pulmonary fat embolism. Secretory phospholipase A2 (sPLA2), a potent inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0e51ae96738f729a36d923fc2bedf7fd
https://pubmed.ncbi.nlm.nih.gov/15040432

Alloimmunization and erythrocyte autoimmunization in transfusion-dependent thalassemia patients of predominantly asian descent

Autor: S T, Singer, V, Wu, R, Mignacca, F A, Kuypers, P, Morel, E P, Vichinsky

Publikováno v: Blood. 96(10)

The development of hemolytic alloantibodies and erythrocyte autoantibodies complicates transfusion therapy in thalassemia patients. The frequency, causes, and prevention of this phenomena among 64 transfused thalassemia patients (75% Asian) were eval

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d8fc21170c6e2cef944286493309b51e
https://pubmed.ncbi.nlm.nih.gov/11405212