Zobrazeno 1 - 6
of 6
pro vyhledávání: '"F A, Eskens"'
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 145(46)
In recent years developments in molecular biology have greatly increased our knowledge about the cellular processes which govern the development of cancer. This has led to the development of anticancer agents that specifically target one of these cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77a9d1deb114409faa7a80a40996f0e6
https://pubmed.ncbi.nlm.nih.gov/11757242
https://pubmed.ncbi.nlm.nih.gov/11757242
Autor:
N C, Levitt, F A, Eskens, K J, O'Byrne, D J, Propper, L J, Denis, S J, Owen, L, Choi, J A, Foekens, S, Wilner, J M, Wood, M, Nakajima, D C, Talbot, W P, Steward, A L, Harris, J, Verweij
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(7)
This Phase I study of MMI270, an p.o. administered matrix metalloproteinase inhibitor, assessed toxicity, pharmacokinetics, and tumor response data and investigated markers of biological activity to recommend a dose for Phase II studies. MMI270 was a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2d231d37f86b6c78040c69fd3879699
https://pubmed.ncbi.nlm.nih.gov/11448904
https://pubmed.ncbi.nlm.nih.gov/11448904
Autor:
F A, Eskens, G A, Greim, C, van Zuylen, I, Wolff, L J, Denis, A S, Planting, F A, Muskiet, J, Wanders, N C, Barbet, L, Choi, R, Capdeville, J, Verweij, A R, Hanauske, U, Bruntsch
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(5)
A single-agent dose-escalating Phase I and pharmacological study of the polyamine synthesis inhibitor SAM 486A was performed. A dosing regimen of four weekly infusions followed by 2 weeks off therapy was studied. Fifty patients were entered into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3566f7b038c716d7babf39b1264308f4
https://pubmed.ncbi.nlm.nih.gov/10815892
https://pubmed.ncbi.nlm.nih.gov/10815892
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(2)
MMI270B is a matrix metalloproteinase inhibitor (MMPI) with in vitro and in vivo activity. To exert optimal target inhibition, MMPI must be given chronically, and therefore, oral bioavailability is important. We analyzed the effect of food intake on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c9424afa3c248c677dad1ce5539ab1e
https://pubmed.ncbi.nlm.nih.gov/10690520
https://pubmed.ncbi.nlm.nih.gov/10690520
Publikováno v:
Journal of neuro-oncology. 44(1)
In most patients with recurrent glioma chemotherapy is the only remaining treatment option. In general results of chemotherapy in these patients are poor, and trials on new regimens are indicated. Because relatively good results have been achieved wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d141d1e293b9830af51f18c913c4c234
https://pubmed.ncbi.nlm.nih.gov/10582670
https://pubmed.ncbi.nlm.nih.gov/10582670
Publikováno v:
Anticancer research. 17(6D)
A patient with a pancreatic islet cell tumor concurrently producing vasoactive intestinal polypeptide (VIP) and calcitonin with related symptoms is presented. The patient was given palliative treatment consisting of octreotide, streptozotocin and 5-f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0046a8c36bcf0b45a5e73d75e655152a
https://pubmed.ncbi.nlm.nih.gov/9494586
https://pubmed.ncbi.nlm.nih.gov/9494586