Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Fırat Uyulur"'
Autor:
Ozlem Yedier-Bayram, Bengul Gokbayrak, Alisan Kayabolen, Ali Cenk Aksu, Ayse Derya Cavga, Ahmet Cingöz, Ezgi Yagmur Kala, Goktug Karabiyik, Rauf Günsay, Beril Esin, Tunc Morova, Fırat Uyulur, Hamzah Syed, Martin Philpott, Adam P. Cribbs, Sonia H. Y. Kung, Nathan A. Lack, Tamer T. Onder, Tugba Bagci-Onder
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-11 (2022)
Abstract Dysregulation of the epigenome due to alterations in chromatin modifier proteins commonly contribute to malignant transformation. To interrogate the roles of epigenetic modifiers in cancer cells, we generated an epigenome-wide CRISPR-Cas9 kn
Externí odkaz:
https://doaj.org/article/349d20f5c38141bd95e9a7af2609f50f
Autor:
Nathan A. Lack, Günsay R, Alisan Kayabolen, Ezgi Yagmur Kala, Tunç Morova, Karabiyik G, Tamer T. Onder, Bengul Gokbayrak, Aksu Ac, Yedier-Bayram O, Ayse Derya Cavga, Fırat Uyulur, Tugba Bagci-Onder
Dysregulation of the epigenome due to alterations in chromatin modifier proteins commonly contribute to malignant transformation. To discover new drug targets for more targeted and personalized therapies, functional interrogation of epigenetic modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::870520b9a0b0e2157587f040171ac311
https://doi.org/10.1101/2021.05.14.444239
https://doi.org/10.1101/2021.05.14.444239
Autor:
Nazife Tolay, Ahmet Cingoz, Udo Oppermann, Zeynep Kahya-Yesil, James E. Dunford, Fidan Seker, Fırat Uyulur, Melike Gezen, Batu Erman, Ezgi Ozyerli-Goknar, Alisan Kayabolen, Tugba Bagci-Onder, Ilknur Sur-Erdem, Mehmet Gönen
Publikováno v:
Cell Death & Disease
Cell Death and Disease
Cell Death and Disease, Vol 10, Iss 12, Pp 1-20 (2019)
Cell Death and Disease
Cell Death and Disease, Vol 10, Iss 12, Pp 1-20 (2019)
Glioblastoma Multiforme (GBM) is the most common and aggressive primary brain tumor. Despite recent developments in surgery, chemo- and radio-therapy, a currently poor prognosis of GBM patients highlights an urgent need for novel treatment strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47c021d12c4d0a9051ab3540987adf8
https://doi.org/10.1038/s41419-019-2107-y
https://doi.org/10.1038/s41419-019-2107-y
Autor:
Fidan, Seker, Ahmet, Cingoz, İlknur, Sur-Erdem, Nazli, Erguder, Alp, Erkent, Fırat, Uyulur, Myvizhi, Esai Selvan, Zeynep Hülya, Gümüş, Mehmet, Gönen, Halil, Bayraktar, Hiroaki, Wakimoto, Tugba, Bagci-Onder
Publikováno v:
Cancers
High mortality rates of glioblastoma (GBM) patients are partly attributed to the invasive behavior of tumor cells that exhibit extensive infiltration into adjacent brain tissue, leading to rapid, inevitable, and therapy-resistant recurrence. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::370b4f077329af67471972eed31704fa
https://pubmed.ncbi.nlm.nih.gov/31731490
https://pubmed.ncbi.nlm.nih.gov/31731490
Autor:
Şule Arı, Gülben Gürhan Sevinç, James E. Dunford, Udo Oppermann, Tunc Morova, Sencer Goklemez, Adam P. Cribbs, Fırat Uyulur, Tamer T. Onder, Martin Philpott, Ayyub Ebrahimi, Kenan Sevinç
Silencing of the somatic cell type-specific genes is a critical yet poorly understood step in reprogramming. To uncover pathways that maintain cell identity, we performed a reprogramming screen using inhibitors of chromatin factors. Here, we identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171f3c3eebe6a49985c86cbe95b12979
https://aperta.ulakbim.gov.tr/record/72505
https://aperta.ulakbim.gov.tr/record/72505
Autor:
Ahmet Cingoz, Alp Erkent, Fırat Uyulur, Fidan Seker, Zeynep H. Gümüş, Myvizhi Esai Selvan, Ilknur Sur-Erdem, Halil Bayraktar, Mehmet Gönen, Tugba Bagci-Onder, Hiroaki Wakimoto, Nazli Erguder
Publikováno v:
Cancers
Cancers, Vol 11, Iss 11, p 1651 (2019)
Volume 11
Issue 11
Cancers, Vol 11, Iss 11, p 1651 (2019)
Volume 11
Issue 11
High mortality rates of glioblastoma (GBM) patients are partly attributed to the invasive behavior of tumor cells that exhibit extensive infiltration into adjacent brain tissue, leading to rapid, inevitable, and therapy-resistant recurrence. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd98ee431fbcf3e7b2223a944721b0c2
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8618
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8618
Autor:
Alp Erkent, Tugba Bagci-Onder, Fırat Uyulur, Fidan Seker, Nathan A. Lack, Hiroaki Wakimoto, Mehmet Gönen, E. Barçin, Nazli Erguder
Publikováno v:
ESMO Open. 3:A97
Introduction Glioblastoma multiforme (GBM) is the most common and aggressive type of glioma with a mean survival of 1 year after diagnosis. A major obstacle in treating GBMs is extensive tumour cell infiltration into the surrounding brain. Despite tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59afb26e9900bb04a1473823e26176b7
https://doi.org/10.1136/esmoopen-2018-eacr25.232
https://doi.org/10.1136/esmoopen-2018-eacr25.232