Defective Glycerol Metabolism in Aquaporin 9 (AQP9) Knockout Mice

Autor: Rojek, Aleksandra M., Skowronski, Mariusz T., Füchtbauer, Ernst-Martin, Füchtbauer, Annette C., Fenton, Robert A., Agre, Peter, Frøkiær, Jørgen, Nielsen, Søren

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2007 Feb . 104(9), 3609-3614.

Externí odkaz: https://www.jstor.org/stable/25426697

The choroid plexus sodium‐bicarbonate cotransporter NBCe2 regulates mouse cerebrospinal fluid pH

Autor: Christensen, Henriette L., Barbuskaite, Dagne, Rojek, Aleksandra, Malte, Hans, Christensen, Inga B., Füchtbauer, Annette C., Füchtbauer, Ernst‐Martin, Wang, Tobias, Praetorius, Jeppe, Damkier, Helle H.

Publikováno v: The Journal of Physiology

Key points Normal pH is crucial for proper functioning of the brain, and disorders increasing the level of CO2 in the blood lead to a decrease in brain pH.CO2 can easily cross the barriers of the brain and will activate chemoreceptors leading to an i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b4fedce49c60c3a0351869e566ca78a9
http://europepmc.org/articles/PMC6166071

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Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice

Autor: Boedtkjer, Ebbe, Prætorius, Jeppe, Matchkov, Vladimir V, Stankevicius, Edgaras, Mogensen, Susie, Füchtbauer, Annette C, Simonsen, Ulf, Füchtbauer, Ernst-Martin, Aalkjaer, Christian

Publikováno v: Boedtkjer, E, Prætorius, J, Matchkov, V V, Stankevicius, E, Mogensen, S, Füchtbauer, A C, Simonsen, U, Füchtbauer, E-M & Aalkjaer, C 2011, ' Disruption of Na+,HCO₃⁻ cotransporter NBCn1 (slc4a7) inhibits NO-mediated vasorelaxation, smooth muscle Ca²⁺ sensitivity, and hypertension development in mice ', Circulation, vol. 124, no. 17, pp. 1819-1829 . https://doi.org/10.1161/CIRCULATIONAHA.110.015974

Disturbances in pH affect artery function, but the mechanistic background remains controversial. We investigated whether Na(+), HCO₃- transporter NBCn1, by regulating intracellular pH(pH₁), influences artery function and blood pressure regulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::748d6bfb2544dcf67aa291dcc0d05166
https://pure.au.dk/portal/da/publications/disruption-of-nahco-cotransporter-nbcn1-slc4a7-inhibits-nomediated-vasorelaxation-smooth-muscle-ca-sensitivity-and-hypertension-development-in-mice(d73a42c4-587b-4417-bed5-5a1196bb2fc2).html

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