Ablation of CCL17-positive hippocampal neurons induces inflammation-dependent epilepsy.

Autor: Eberhard J; Immunology & Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Henning L; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, Bonn, Germany.; Deutsche Forschungsgemeinschaft, Bonn, Germany., Fülle L; Immunology & Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.; Business Development Europe Research Services, WuXi Biologics, Leverkusen, Germany., Knöpper K; Immunology & Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.; Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA., Böhringer J; Immunology & Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Graelmann FJ; Immunology & Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Hänschke L; Molecular Developmental Biology, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Kenzler J; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, Bonn, Germany.; Sanofi-Aventis Deutschland, Medical Operations General Medicines in Germany, Switzerland, Austria (GSA), Berlin, Germany., Brosseron F; German Center for Neurodegenerative Diseases, Bonn, Germany., Heneka MT; German Center for Neurodegenerative Diseases, Bonn, Germany.; Luxembourg Center for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., Domingos AI; Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, UK., Eyerich S; Institute for Medical Microbiology, Immunology, and Hygiene, Technical University of Munich, Munich, Germany.; ZAUM-Center of Allergy and Environment, Technical University and Helmholtz Center Munich, Munich, Germany., Lochner M; Institute for Medical Microbiology, Immunology, and Hygiene, Technical University of Munich, Munich, Germany.; Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany., Weighardt H; Immunology & Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Bedner P; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, Bonn, Germany., Steinhäuser C; Institute of Cellular Neurosciences, Medical Faculty, University of Bonn, Bonn, Germany., Förster I; Immunology & Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.

Publikováno v: Epilepsia [Epilepsia] 2024 Nov 28. Date of Electronic Publication: 2024 Nov 28.

Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis.

Autor: Graelmann FJ; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Gondorf F; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Majlesain Y; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Niemann B; Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Germany., Klepac K; Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Germany., Gosejacob D; Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Germany., Gottschalk M; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Mayer M; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Iriady I; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Hatzfeld P; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Lindenberg SK; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Wunderling K; Biochemistry & Cell Biology of Lipids, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Thiele C; Biochemistry & Cell Biology of Lipids, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Abdullah Z; Institute of Molecular Medicine and Experimental Immunology, University Hospital Bonn, University of Bonn, Germany., He W; Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany., Hiller K; Braunschweig Integrated Centre of Systems Biology (BRICS), Technische Universität Braunschweig, Braunschweig, Germany., Händler K; PRECISE Platform for Single cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn and West German Genome Center, Bonn, Germany; Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany; Institute of Human Genetics, Universitätsklinikum Schleswig-Holstein, University of Lübeck and University of Kiel, 23562 Lübeck, Germany., Beyer MD; PRECISE Platform for Single cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn and West German Genome Center, Bonn, Germany; Immunogenomics & Neurodegeneration, German Center for Neurodegenerative Diseases, Bonn, Germany., Ulas T; PRECISE Platform for Single cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn and West German Genome Center, Bonn, Germany; Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Pfeifer A; Institute of Pharmacology and Toxicology, University Hospital Bonn, University of Bonn, Germany., Esser C; IUF-Leibniz Research Institute for Environmental Medicine gGmbH, Düsseldorf, Germany., Weighardt H; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany; IUF-Leibniz Research Institute for Environmental Medicine gGmbH, Düsseldorf, Germany., Förster I; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany. Electronic address: irmgard.foerster@uni-bonn.de., Reverte-Salisa L; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany. Electronic address: laia@uni-bonn.de.

Publikováno v: Molecular metabolism [Mol Metab] 2024 Jul; Vol. 85, pp. 101963. Date of Electronic Publication: 2024 May 29.

Dysregulation of stress erythropoiesis and enhanced susceptibility to Salmonella Typhimurium infection in AhR-deficient mice.

Autor: Mayer M; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Cengiz-Dartenne SC; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany.; Department of Vascular- and Endovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine-University, Düsseldorf, Germany., Thiem M; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany.; The Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Hatzfeld P; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Semeniuk A; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany.; The Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Wang N; The Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Strugnell RA; The Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Förster I; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany., Weighardt H; Immunology and Environment, Life and Medical Sciences (LIMES) Institute, University of Bonn, Germany.; Innate immunity and extrinsic skin aging, IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Jun 06. Date of Electronic Publication: 2024 Jun 06.

The GM-CSF/CCL17 pathway in obesity-associated osteoarthritic pain and disease in mice.

Autor: Shin H; Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria 3050 Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Prasad V; Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria 3050 Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Lupancu T; Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria 3050 Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Malik S; Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria 3050 Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Achuthan A; Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria 3050 Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Biondo M; CSL Ltd, Bio21 Institute, Parkville, Victoria 3050 Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Kingwell BA; CSL Ltd, Bio21 Institute, Parkville, Victoria 3050 Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Thiem M; Immunology and Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Gottschalk M; Immunology and Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Weighardt H; Immunology and Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Förster I; Immunology and Environment, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., de Steiger R; Department of Surgery, Epworth Healthcare, University of Melbourne, Richmond, Victoria 3121, Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Hamilton JA; Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria 3050 Australia; Australian Institute for Musculoskeletal Science (AIMSS), The University of Melbourne and Western Health, St. Albans, Victoria 3021, Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia., Lee KM; Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria 3050 Australia; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia. Electronic address: mingchinl@unimelb.edu.au.

Publikováno v: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2023 Oct; Vol. 31 (10), pp. 1327-1341. Date of Electronic Publication: 2023 May 22.

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