Vasoactive intestinal peptide induces IL-8 production in human colonic epithelial cells via MAP kinase-dependent and PKA-independent pathways

Autor: Jean-Paul Galmiche, Anne Jarry, Tsvetelina Oreshkova, Marc G. Denis, Christian L. Laboisse, Férial Toumi, Michel Neunlist

Publikováno v: Biochemical and Biophysical Research Communications. 317:187-191

Vasoactive intestinal peptide (VIP) has been shown to be a key regulator of intestinal epithelial functions such as mucus and chloride secretion, paracellular permeability, and cell proliferation. However, its regulatory role in intestinal epithelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9912d56c9b0cc48ca6a6ce2648d358e
https://doi.org/10.1016/j.bbrc.2004.03.033

Effects of peptides derived from dietary proteins on mucus secretion in rat jejunum

Autor: Jean Claustre, Jean Alain Chayvialle, Gerard Jourdan, Férial Toumi, Aurélien Trompette, Pascale Plaisancié, Henri Guignard

Publikováno v: American Journal of Physiology-Gastrointestinal and Liver Physiology. 283:G521-G528

The hypothesis that dietary proteins or their hydrolysates may regulate intestinal mucin discharge was investigated in the isolated vascularly perfused rat jejunum using an enzyme-linked immunosorbent assay for rat intestinal mucins. On luminal admin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cd530f051965821811cc000ea858f8
https://doi.org/10.1152/ajpgi.00535.2001

Long acting β2-agonist and corticosteroid restore airway glandular cell function altered by bacterial supernatant

Autor: Jean-Marie Zahm, C. Kileztky, Malcolm Johnson, Christelle Coraux, Gérard Balossier, Béatrice Nawrocki-Raby, Philippe Birembaut, Jean Michel, Férial Toumi, Franck Delavoie

Publikováno v: Respiratory Research
Respiratory Research, BioMed Central, 2010, 11 (1), pp.6. ⟨10.1186/1465-9921-11-6⟩
Respiratory Research, 2010, 11 (1), pp.6. ⟨10.1186/1465-9921-11-6⟩
Respiratory Research, Vol 11, Iss 1, p 6 (2010)

Background: Staphylococcus aureus releases virulence factors (VF) that may impair the innate protective functions of airway cells. The aim of this study was to determine whether a long-acting b2 adrenergic receptor agonist (salmeterol hydroxynaphthoa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a63c3cf7915dcb775a716835639b0e8
https://www.hal.inserm.fr/inserm-00663538/file/1465-9921-11-6.pdf

T1675 EGF Chronically Upregulates Colonic Epithelial Cl− Secretion By Mechanisms Involving PI3-K, ERK and p38 MAPK and Increases in Transport Protein Expression

Autor: Fiona O'Mahony, Férial Toumi, Stephen J. Keely, Magdalena S. Mroz

Publikováno v: Gastroenterology. 136:A-555

Background: Cholinergic activation of epithelial muscarinic M3 receptors (M3R) rapidly promotes colonic Cland fluid secretion. However, whether M3R activation has long-term consequences for epithelial secretory capacity is unknown. Aim: To investigat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30f0cde855e4af1bd604a185b4f07a88
https://doi.org/10.1016/s0016-5085(09)62555-5

Peptides derived from casein induce mucus secretion in rat jejunum: Involvement of opioid stimulation

Autor: Aurélien Trompette, Férial Toumi, Henri Guignard, Jean Claustre, Gerard Jourdan, Jean-Alain Chayvialle

Publikováno v: Gastroenterology. 120:A675-A675

leads to a marked inflammatory response with secretion of IL6, IL8 and TNFe. Breast Milk and Modulin significantly decreased IL6, IL8 and TNFe secretion by between 50 and 75%. Boost decreased IL8 secretion but had no effect on IL6 or TNF~ secretion.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2898c4dcbdd97219357ed7a306def8
https://doi.org/10.1016/s0016-5085(01)83358-8