Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Félix Weis"'
Autor:
Luciano G. Dolce, Aubree A. Zimmer, Laura Tengo, Félix Weis, Mary Anne T. Rubio, Juan D. Alfonzo, Eva Kowalinski
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The deamination of all adenosines in the wobble base position is essential to empower the individual tRNA to decode several codons. Here, the authors present the cryo-EM structure of the tRNA-bound ADAT2/3 deaminase, revealing how the geometry-specif
Externí odkaz:
https://doaj.org/article/99e518943ee04156af1a7ea3c09e57ba
Autor:
Ewa Bielczyk-Maczyńska, Laure Lam Hung, Lauren Ferreira, Tobias Fleischmann, Félix Weis, Antonio Fernández-Pevida, Steven A Harvey, Neha Wali, Alan J Warren, Inês Barroso, Derek L Stemple, Ana Cvejic
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005677 (2015)
Ribosome biogenesis is a ubiquitous and essential process in cells. Defects in ribosome biogenesis and function result in a group of human disorders, collectively known as ribosomopathies. In this study, we describe a zebrafish mutant with a loss-of-
Externí odkaz:
https://doaj.org/article/a666b779780c4de7aeb4d840e748fa47
Kinetoplastid parasites, such as trypanosomes or leishmania, rely on RNA-templated RNA editing to mature mitochondrial cryptic pre-mRNAs into functional protein-coding transcripts. Processive pan-editing of multiple editing blocks within a single tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f1c716381d14baf0e78bb6e032d480
https://doi.org/10.1101/2023.02.01.526499
https://doi.org/10.1101/2023.02.01.526499
Autor:
Luciano G. Dolce, Aubree A. Zimmer, Laura Tengo, Félix Weis, Mary Anne T. Rubio, Juan D. Alfonzo, Eva Kowalinski
The essential deamination of adenosine A34 to inosine at the wobble base is the individual tRNA modification with the greatest effects on mRNA decoding, empowering a single tRNA to translate three different codons. To date, many aspects of how eukary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18c39ec92b2b9fe3c4fcc2973884ed36
https://doi.org/10.1101/2022.06.16.496122
https://doi.org/10.1101/2022.06.16.496122
Autor:
Rahul Sharma, Michael Adams, Simonne Griffith-Jones, Tobias Sahr, Laura Gomez-Valero, Felix Weis, Michael Hons, Sarah Gharbi, Rayene Berkane, Alexandra Stolz, Carmen Buchrieser, Sagar Bhogaraju
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Legionella pneumophila (LP) secretes more than 300 effectors into the host cytosol to facilitate intracellular replication. One of these effectors, SidH, 253 kDa in size with no sequence similarity to proteins of known function is toxic when
Externí odkaz:
https://doaj.org/article/2d88ff0f17214a348ccac44f567c6f37
Autor:
Lisa Hanke, Lea K. Jessen, Felix Weisheit, Krathika Bhat, Ulrike Westernströer, Dieter Garbe-Schönberg, Regine Willumeit-Römer, Eckhard Quandt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Freestanding thin films of Mg–Li (magnesium–lithium) alloys with a Li mass fraction between 1.6% (m/m) and 9.5% (m/m) were prepared and studied with respect to their structure and degradation properties. With increasing Li content, the m
Externí odkaz:
https://doaj.org/article/333f253085d844f088e26da364437de5
Autor:
Jianjiang Hu, Xavier Serra‐Picamal, Gert‐Jan Bakker, Marleen Van Troys, Sabina Winograd‐Katz, Nil Ege, Xiaowei Gong, Yuliia Didan, Inna Grosheva, Omer Polansky, Karima Bakkali, Evelien Van Hamme, Merijn vanErp, Manon Vullings, Felix Weiss, Jarama Clucas, Anna M Dowbaj, Erik Sahai, Christophe Ampe, Benjamin Geiger, Peter Friedl, Matteo Bottai, Staffan Strömblad
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 6, Pp n/a-n/a (2023)
Abstract High‐content image‐based cell phenotyping provides fundamental insights into a broad variety of life science disciplines. Striving for accurate conclusions and meaningful impact demands high reproducibility standards, with particular rel
Externí odkaz:
https://doaj.org/article/732ee8bfa8294913a63eccb0f9aa6998
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Legionella pneumophila (LP) employs the metaeffector SidJ to suppress the toxicity of SdeA and other LP SidE effector family members by catalysing the glutamylation of the catalytic Glu residue. Here, the authors present the cryo-EM structures of Sid
Externí odkaz:
https://doaj.org/article/330293d1384b47d989742f3a1d1d4179
Publikováno v:
Wearable Technologies, Vol 3 (2022)
Climbing stairs can become a daily obstacle for elderly people, and an exoskeleton can assist here. However, the exoskeletons that are designed to assist stair climbing are actuated in different ways. To find a minimal actuation configuration, we ide
Externí odkaz:
https://doaj.org/article/fbabde01dfe540aeb9b0cb3a0df2acdd
Publikováno v:
eLife, Vol 11 (2022)
Cryogenic electron microscopy has become an essential tool for structure determination of biological macromolecules. In practice, the difficulty to reliably prepare samples with uniform ice thickness still represents a barrier for routine high-resolu
Externí odkaz:
https://doaj.org/article/6102dea3224443ef8d777696f1e28eff