Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Félix Sierra-Ramírez"'
Autor:
Sara L. Morales-Lázaro, Itzel Llorente, Félix Sierra-Ramírez, Ana E. López-Romero, Miguel Ortíz-Rentería, Barbara Serrano-Flores, Sidney A. Simon, León D. Islas, Tamara Rosenbaum
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
TRPV1 channels are known to mediate pathological pain and itch. Here, the authors find a naturally occurring fatty acid, oleic acid, acts as a TRPV1 antagonist and can modulate capsaicin and histamine-mediated pain and itch response in mouse models.
Externí odkaz:
https://doaj.org/article/54aa5cbb43274e3e806447b790722427
Autor:
Ricardo González-Ramírez, Sara L. Morales-Lázaro, Sidney A. Simon, Rebeca Juárez-Contreras, Itzel Llorente, Miguel Ortíz-Rentería, León D. Islas, Marcia Hiriart, Tamara Rosenbaum, Félix Sierra-Ramírez
Publikováno v:
Proceedings of the National Academy of Sciences. 115
The Transient Receptor Potential Vanilloid 1 (TRPV1) ion channel is expressed in nociceptors where, when activated by chemical or thermal stimuli, it functions as an important transducer of painful and itch-related stimuli. Although the interaction o
Autor:
Félix Sierra-Ramírez, Itzel Llorente, Miguel Ortíz-Rentería, Sidney A. Simon, Barbara Serrano-Flores, Tamara Rosenbaum, Sara L. Morales-Lázaro, Ana E. López-Romero, León D. Islas
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The transient receptor potential vanilloid 1 (TRPV1) ion channel is mainly found in primary nociceptive afferents whose activity has been linked to pathophysiological conditions including pain, itch and inflammation. Consequently, it is important to
Autor:
Tamara Rosenbaum, Carlos Manlio Diaz-Garcia, Barbara Serrano-Flores, Itzel Llorente, Sidney A. Simon, Sara L. Morales-Lázaro, Marcia Hiriart, Félix Sierra-Ramírez
Publikováno v:
Biophysical Journal. 106:333a
TRPV1 channels are important mediators of nociceptive and inflammation processes. They can be activated by several types of physical and chemical stimuli including high temperatures, low extracellular or high intracellular pH and by a direct interact