Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Félix A. Urra"'
Autor:
Jessica Astorga, Naschla Gasaly, Karen Dubois-Camacho, Marjorie De la Fuente, Glauben Landskron, Klaas Nico Faber, Félix A. Urra, Marcela A. Hermoso
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/d449104c179341eda9792ec7cadb3c46
Autor:
Matías Monroy-Cárdenas, Cristopher Almarza, Paulina Valenzuela-Hormazábal, David Ramírez, Félix A. Urra, Maximiliano Martínez-Cifuentes, Ramiro Araya-Maturana
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8334 (2024)
α-glucosidase, a pharmacological target for type 2 diabetes mellitus (T2DM), is present in the intestinal brush border membrane and catalyzes the hydrolysis of sugar linkages during carbohydrate digestion. Since α-glucosidase inhibitors (AGIs) modu
Externí odkaz:
https://doaj.org/article/ea3865e24dd84c8599b81ce082bb238d
Autor:
Maria Jesus Vera, Iván Ponce, Cristopher Almarza, Gonzalo Ramirez, Francisco Guajardo, Karen Dubois-Camacho, Nicolás Tobar, Félix A. Urra, Jorge Martinez
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 801 (2024)
While cytostatic chemotherapy targeting DNA is known to induce genotoxicity, leading to cell cycle arrest and cytokine secretion, the impact of these drugs on fibroblast–epithelial cancer cell communication and metabolism remains understudied. Our
Externí odkaz:
https://doaj.org/article/0a1e2488c78c42d28465d3c802a44e23
Publikováno v:
Herpetozoa, Vol 35, Iss , Pp 155-158 (2022)
In this work, we describe the first records of head-wobble behaviour for Tachymenis peruviana and T. chilensis coronellina. We analyse this behaviour (occurrence, frequency) and accompanying displays in both species. Of particular note is that T. ch.
Externí odkaz:
https://doaj.org/article/41f57a7c74634388a11de2bfe6bf1e85
Autor:
Matías Monroy-Cárdenas, Víctor Andrades, Cristopher Almarza, María Jesús Vera, Jorge Martínez, Rodrigo Pulgar, John Amalraj, Ramiro Araya-Maturana, Félix A. Urra
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1597 (2023)
Mitochondrial Complex I plays a crucial role in the proliferation, chemoresistance, and metastasis of breast cancer (BC) cells. This highlights it as an attractive target for anti-cancer drugs. Using submitochondrial particles, we identified FRV–1,
Externí odkaz:
https://doaj.org/article/7be582599e6d4ba1a8ef695290a23627
Autor:
Jessica Astorga, Naschla Gasaly, Karen Dubois-Camacho, Marjorie De la Fuente, Glauben Landskron, Klaas Nico Faber, Félix A. Urra, Marcela A. Hermoso
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inflammatory Bowel Disease (IBD) is characterized by a loss of intestinal barrier function caused by an aberrant interaction between the immune response and the gut microbiota. In IBD, imbalance in cholesterol homeostasis and mitochondrial bioenerget
Externí odkaz:
https://doaj.org/article/8ac7b5a3542f4b9ab2c4452751ecb692
Autor:
Daniel Torrejón, Javier Cárdenas, Diana Juárez, Jordano Espinoza, Alex Proleón, Andrés Agurto-Arteaga, Fanny Lazo, Mariana Leguía, Félix A. Urra, Eladio F. Sánchez, Carlos Chávez-Olortegui, Dan E. Vivas-Ruiz, Armando Yarlequé
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11161 (2023)
RNA purification and cDNA synthesis represents the starting point for molecular analyses of snake venom proteins-enzymes. Usually, the sacrifice of snakes is necessary for venom gland extraction to identify protein-coding transcripts; however, the ve
Externí odkaz:
https://doaj.org/article/96bb74c6f3014c749934edb10a250298
Autor:
Dan E. Vivas-Ruiz, Paola Rosas, Alex Proleón, Daniel Torrejón, Fanny Lazo, Ana Belén Tenorio-Ricca, Francisco Guajardo, Cristopher Almarza, Víctor Andrades, Jessica Astorga, Daniel Oropesa, Jorge Toledo, María Jesús Vera, Jorge Martínez, Ramiro Araya-Maturana, Karen Dubois-Camacho, Marcela A. Hermoso, Valéria G. Alvarenga, Eladio Flores Sanchez, Armando Yarlequé, Luciana Souza Oliveira, Félix A. Urra
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1533 (2023)
From the venom of the Bothrops pictus snake, an endemic species from Peru, we recently have described toxins that inhibited platelet aggregation and cancer cell migration. In this work, we characterize a novel P-III class snake venom metalloproteinas
Externí odkaz:
https://doaj.org/article/43eed5d3f77f43fea778f614b04bc86b
An Emergent Role for Mitochondrial Bioenergetics in the Action of Snake Venom Toxins on Cancer Cells
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Beyond the role of mitochondria in apoptosis initiation/execution, some mitochondrial adaptations support the metastasis and chemoresistance of cancer cells. This highlights mitochondria as a promising target for new anticancer strategies. Emergent e
Externí odkaz:
https://doaj.org/article/6dba963cdccf4777ae15048caf9d8cfc
Autor:
Yarela Herrera, Sebastián Fuentes-Retamal, Ulrike Kemmerling, María Elisa Peichoto, Juan Carlos Ortiz, Félix A. Urra
Publikováno v:
Biology, Vol 11, Iss 12, p 1788 (2022)
Although the rear-fanged snake Galvarinus chilensis chilensis (formerly named Tachymenis ch. chilensis) causes ophidian accidents with clinical importance in Chile, the anatomical and histological characterizations of the venom delivery system (venom
Externí odkaz:
https://doaj.org/article/945e9662cee5465cad3a8a00a9b454ad