Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Fátima, Lucas"'
Autor:
Yvett Sosa, Bhav Kapur, Jessica Hurtak, Laura J. Kingsley, Hao Wu, Stefanie Gruber, Herbert Nar, Saad Khattabi, Jesus Seco Moral, Maria Fátima Lucas, Caterina Martin, Nikola Lončar, Frederic Buono, Noah Pefaur, Andrew E. Nixon, Jinhua J. Song
Publikováno v:
Frontiers in Chemical Biology, Vol 3 (2024)
Introduction: Biocatalysis, particularly through engineered enzymes, presents a cost-effective, efficient, and eco-friendly approach to compound synthesis. We sought to identify ketoreductases capable of synthesizing optically pure alcohols or ketone
Externí odkaz:
https://doaj.org/article/9cf8af4a995a453ca62582f81e558283
Autor:
André Taborda, Tomás Frazão, Miguel V. Rodrigues, Xavier Fernández-Luengo, Ferran Sancho, Maria Fátima Lucas, Carlos Frazão, Eduardo P. Melo, M. Rita Ventura, Laura Masgrau, Patrícia T. Borges, Lígia O. Martins
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract C-glycosides are natural products with important biological activities but are recalcitrant to degradation. Glycoside 3-oxidases (G3Oxs) are recently identified bacterial flavo-oxidases from the glucose-methanol-coline (GMC) superfamily that
Externí odkaz:
https://doaj.org/article/37311c7613634812a6125424c9458195
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
In recent years, simulations have been used to great advantage to understand the structural and dynamic aspects of distinct enzyme immobilization strategies, as experimental techniques have limitations in establishing their impact at the molecular le
Externí odkaz:
https://doaj.org/article/6e626200dee24d028b112507a14d64c1
Autor:
Patrícia T. Borges, Diogo Silva, Tomás F.D. Silva, Vânia Brissos, Marina Cañellas, Maria Fátima Lucas, Laura Masgrau, Eduardo P. Melo, Miguel Machuqueiro, Carlos Frazão, Lígia O. Martins
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3899-3910 (2022)
DyP-type peroxidases (DyPs) are microbial enzymes that catalyze the oxidation of a wide range of substrates, including synthetic dyes, lignin-derived compounds, and metals, such as Mn2+ and Fe2+, and have enormous biotechnological potential in bioref
Externí odkaz:
https://doaj.org/article/ff8a63eb5f1e4897b6318690ddd37c7f
Autor:
Patrícia T. Borges, Diogo Silva, Tomás F.D. Silva, Vânia Brissos, Marina Cañellas, Maria Fátima Lucas, Laura Masgrau, Eduardo P. Melo, Miguel Machuqueiro, Carlos Frazão, Lígia O. Martins
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 22, Iss , Pp 2- (2023)
Externí odkaz:
https://doaj.org/article/26503200f21247e5bf9087c5d5674614
Autor:
Qing Liu, Arman Beyraghdar Kashkooli, David Manzano, Irini Pateraki, Lea Richard, Pim Kolkman, Maria Fátima Lucas, Victor Guallar, Ric C.H. de Vos, Maurice C. R. Franssen, Alexander van der Krol, Harro Bouwmeester
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Guaianolides are pharmaceutically interesting molecules. Here, the authors isolate the enzyme kauniolide synthase from feverfew, show that it converts constunolide into a guaianolide via an unusual mechanism of action, and reconstruct the full kaunio
Externí odkaz:
https://doaj.org/article/2bca8e4a2e3b473f86c74e293fd3548d
Autor:
Vânia Brissos, Patrícia T. Borges, Reyes Núñez-Franco, Maria Fátima Lucas, Carlos Frazão, Emanuele Monza, Laura Masgrau, Tiago N. Cordeiro, Lígia O. Martins
Publikováno v:
ACS Catalysis
Laccases are in increasing demand as innovative solutions in the biorefinery fields. Here, we combine mutagenesis with structural, kinetic, and in silico analyses to characterize the molecular features that cause the evolution of a hyperthermostable
Autor:
RODRIGO DA SILVA OLIVEIRA, MONIQUE RODRIGUES PEREIRA, VIRGINIA SILVA CARVALHO, ELIZABETH DE FÁTIMA LUCAS, GERALDO DE AMARAL GRAVINA
Publikováno v:
Revista Brasileira de Fruticultura, Vol 37, Iss 2, Pp 273-280 (2015)
Este trabalho teve como objetivo avaliar a substituição total ou parcial do ágar por amidos de milho e mandioca e da esterilizaçãofísica em autoclave pela esterilização química com hipoclorito de sódio (NaClO) no desenvolvimento de mudas de
Externí odkaz:
https://doaj.org/article/1f7a68cc346849be98a961c0bd385d7a
Autor:
MONIQUE RODRIGUES PEREIRA, VIRGINIA SILVA CARVALHO, ELIZABETH DE FÁTIMA LUCAS, GERALDO DE AMARAL GRAVINA
Publikováno v:
Revista Brasileira de Fruticultura, Vol 37, Iss 2, Pp 528-533 (2015)
Este trabalho objetivou reduzir o custo de produção dos meios de cultura pela substituição do ágar por amido de milho e da esterilização física em autoclave pela esterilização química com hipoclorito de sódio (NaClO) em mudas de abacaxize
Externí odkaz:
https://doaj.org/article/97872d167bed44a3a69f0ba998b43d9b
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 10, p e1005787 (2017)
Vanillyl alcohol oxidase (VAO) is a homo-octameric flavoenzyme belonging to the VAO/PCMH family. Each VAO subunit consists of two domains, the FAD-binding and the cap domain. VAO catalyses, among other reactions, the two-step conversion of p-creosol
Externí odkaz:
https://doaj.org/article/64c79ad3f79f4d6085209069939854dc