The role of DC-SIGN as a trans-receptor in infection by MERS-CoV

Autor: Nuria Labiod, Joanna Luczkowiak, María M. Tapia, Fátima Lasala, Rafael Delgado

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

DC-SIGN is a C-type lectin expressed in myeloid cells such as immature dendritic cells and macrophages. Through glycan recognition in viral envelope glycoproteins, DC-SIGN has been shown to act as a receptor for a number of viral agents such as HIV,

Externí odkaz: https://doaj.org/article/f77a81a2e8504c4fb1aadb5993d42ae8

Survey of Crimean-Congo Hemorrhagic Fever Enzootic Focus, Spain, 2011–2015

Autor: Ana Negredo, Miguel Ángel Habela, Eva Ramírez de Arellano, Francisco Diez, Fátima Lasala, Pablo López, Ana Sarriá, Nuria Labiod, Rafael Calero-Bernal, Miguel Arenas, Antonio Tenorio, Agustín Estrada-Peña, Maria Paz Sánchez-Seco

Publikováno v: Emerging Infectious Diseases, Vol 25, Iss 6, Pp 1177-1184 (2019)

During 2011–2015, we conducted a Crimean-Congo hemorrhagic fever virus (CCHFV) survey in captured ticks that were feeding mainly on wild and domestic ungulates in Spain, where presence of this virus had been reported previously. We detected CCHFV R

Externí odkaz: https://doaj.org/article/bd901e70ffcb45e6a2dfdfe00ba1b36d

N′-phenylacetohydrazide derivatives as potent Ebola virus entry inhibitors with an improved pharmacokinetic profile

Autor: Alfonso Garcia-Rubia, Fátima Lasala, Tiziana Ginex, Marcos Morales-Tenorio, Catherine Olal, Michelle Heung, Paola Oquist, Inmaculada Galindo, Miguel Ángel Cuesta-Geijo, José M. Casasnovas, Nuria E. Campillo, Ángeles Canales, Covadonga Alonso, Ana Martínez, César Muñoz-Fontela, Rafael Delgado, Carmen Gil

19 p.-6 fig.-7 tab.-1 graph. abst.
Ebola virus (EBOV) is a single-strand RNA virus belonging to the Filoviridae family, which has been associated to most Ebola virus disease outbreaks to date, including the West African and the North Kivu epidem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925a150a28b8f780af50eb0d0680aa4b
http://hdl.handle.net/10261/305819

Cross neutralization of SARS‐CoV‐2 omicron subvariants after repeated doses of COVID‐19 mRNA vaccines

Autor: Joanna Luczkowiak, Gonzalo Rivas, Nuria Labiod, Fátima Lasala, Marta Rolo, Jaime Lora‐Tamayo, Mikel Mancheno‐Losa, David Rial‐Crestelo, Alfredo Pérez‐Rivilla, María Dolores Folgueira, Rafael Delgado

Publikováno v: Journal of Medical Virology. 95

We have measured the humoral response to messenger RNA (mRNA) vaccines in COVID-19 naïve and convalescent individuals. Third doses of mRNA COVID-19 vaccines induced a significant increase in potency and breadth of neutralization against SARS-CoV-2 v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd04ee3dd4cebd92d73b9b9cb77a80e6
https://doi.org/10.1002/jmv.28268

Topological and Multivalent Effects in Glycofullerene Oligomers as EBOLA Virus Inhibitors

Autor: Javier Ramos-Soriano, Beatriz M. Illescas, Alfonso Pérez-Sánchez, Raquel Sánchez-Bento, Fátima Lasala, Javier Rojo, Rafael Delgado, Nazario Martín

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 5083
Repositorio Institucional del Instituto Madrileño de Estudios Avanzados en Nanociencia
instname
E-Prints Complutense. Archivo Institucional de la UCM

The synthesis of new biocompatible antiviral materials to fight against the development of multidrug resistance is being widely explored. Due to their unique globular structure and excellent properties, [60]fullerene-based antivirals are very promisi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1479afc38011c3b8bdcc319805c6ec1e
http://hdl.handle.net/20.500.12614/2853