UV SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVE DETERMINATION OF AGOMELATINE IN COATED TABLETS

Autor: Fábio de Souza Barbosa, Vanise Coty Rodrigues, Nadia Maria Volpato, Elfrides E. S. Schapoval, Martin Steppe, Cássia V. Garcia, Andreas S. L. Mendez

Publikováno v: Drug Analytical Research, Vol 1, Iss 2, Pp 24-29 (2017)

UV spectrophotometry is an analytical technique used routinely for qualitative and quantitative assay due the low cost and reliability during analysis. In this work, it was validated a quantitative UV method for determination of agomelatine in coated

Externí odkaz: https://doaj.org/article/5eca16c3935448cc8a25202f78531ec3

pH effect on stability and kinetics degradation of nitazoxanide in solution

Autor: Julia Medeiros Sorrentino, Andreas Sebastian Loureiro Mendez, Nadia Maria Volpato, Fábio de Souza Barbosa, Leonardo Capra Pezzi, Martin Steppe

Publikováno v: Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Drug Analytical Research; v. 4, n. 1 (2020); 12-17
Drug Analytical Research, Vol 4, Iss 1, Pp 12-17 (2020)

Stability studies correspond to a set of tests designed to assess changes in the quality of a given drug over time and under the influence of a number of factors. Among these factors, pH plays an important role, due to the catalytic effect that hydro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06315b186289a8387aed040ed0f8439f
https://doi.org/10.22456/2527-2616.101465

A set of synthetic data, antibacterial evaluation and bacterial interaction with lipid-core nanocapsules containing fusidic acid

Autor: Danieli Rosane Dallemole, Aline de Cristo Soares Alves, Vladimir Lavayen, Fábio de Souza Barbosa, Adriana Raffin Pohlmann, Martin Steppe, Barbara Zoche Pacheco, Rodrigo Cé, Silvia Stanisçuaski Guterres, Taiane M. Ciocheta

Publikováno v: Data in Brief, Vol 36, Iss, Pp 107089-(2021)
Data in Brief

A set of synthetic data, of antibacterial evaluation against gram-positive bacteria, as well as, the interaction of bacterial with lipid-core nanocapsules containing fusidic acid is presented here. In this data set, the analytical data are detailed;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2996662116b354a8e157e6c0b8110608
http://www.sciencedirect.com/science/article/pii/S2352340921003735

Stability study of doripenem antibiotic applying LC-ESI-Q-TOF method and in silico prediction: An analytical investigation focused on degradation products

Autor: Sarah Eller, Fábio de Souza Barbosa, Tiago Franco de Oliveira, Fávero Reisdorfer Paula, Elfrides Eva Scherman Schapoval, Andreas Sebastian Loureiro Mendez, Leonardo Capra Pezzi

Publikováno v: Microchemical Journal. 166:106230

In the present study, the stability of the antibiotic doripenem was evaluated with a focus on identifying the degradation products generated. For this, a method by LC-ESI-Q-TOF was developed and validated. Also, as an auxiliary tool in the identifica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b776f4b221fdccfa140af647320ddbaa
https://doi.org/10.1016/j.microc.2021.106230

Antibacterial activity against Gram-positive bacteria using fusidic acid-loaded lipid-core nanocapsules

Autor: Adriana Raffin Pohlmann, Vladimir Lavayen, Fábio de Souza Barbosa, Danieli Rosane Dallemole, Aline de Cristo Soares Alves, Barbara Zoche Pacheco, Martin Steppe, Taiane M. Ciocheta, Silvia Stanisçuaski Guterres, Rodrigo Cé

Publikováno v: Reactive and Functional Polymers. 162:104876

We proposed the development of fusidic acid-loaded lipid-core nanocapsules to improve the in vitro antibacterial activity of the drug against Staphylococcus aureus, Enterococcus faecalis and Staphylococcus epidermidis strains. The effect of the parti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44ddbfd316f4a62cc0a16102ecb5f75e
https://doi.org/10.1016/j.reactfunctpolym.2021.104876