Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Fábio Fagundes da Rocha"'
Autor:
Frederico Argollo Vanderlinde, Higor Frutuoso Landim, Elson Alves Costa, Pablinny Moreira Galdino, Maria Aparecida Medeiros Maciel, Gineide Conceição dos Anjos, David do Carmo Malvar, Wellington da Silva Côrtes, Fábio Fagundes da Rocha
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 45, Iss 3, Pp 437-442 (2009)
The stem bark of Anacardium occidentale L. (Anacardiaceae), commonly called cashew, is used in Brazilian traditional medicine for the treatment of gastric and inflammatory disorders. The present study was carried out to investigate the in vivo anti-i
Externí odkaz:
https://doaj.org/article/742d9970baf54a4cbc7954e06b611230
Autor:
Lorrane Kelle da Silva Moreira, Larissa Córdova Turones, Hericles Mesquita Campos, Aline Martins Nazareth, Douglas Vieira Thomaz, Eric de Souza Gil, Paulo César Ghedini, Fábio Fagundes da Rocha, Ricardo Menegatti, James Oluwagbamigbe Fajemiroye, Elson Alves Costa
Publikováno v:
Life sciences. 312
Oxidative stress, impaired antioxidant defense and neuroinflammation are often associated with the onset and progression of neuropsychiatric diseases. Conversely, several piperazine compounds presents beneficial neuropharmacological effects as well a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5f74a24b3f860ba31f25c355d9263c
https://pubmed.ncbi.nlm.nih.gov/36402170
https://pubmed.ncbi.nlm.nih.gov/36402170
Autor:
Osmar N. Silva, Samuel A Fava, Emerson H Gomes, Emerith Mayra Hungria Pinto, Dayane Moreira da Silva, José Luís Rodrigues Martins, Elson Alves Costa, Paulo César Ghedini, Fábio Fagundes da Rocha, James Oluwagbamigbe Fajemiroye, Isaac Yves Lopes de Macêdo, Eric de Souza Gil, Murilo Ferreira de Carvalho
Publikováno v:
Current pharmaceutical design. 28(8)
Background: Gastric ulcer has been a major cause of morbidity and mortality worldwide, and it has been linked to factors such as nutritional deficiency, smoking, stress, and continuous intake of non-steroidal anti-inflammatory drugs (NSAIDs). The sea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30be7a6647d2693ea6d7032899a7d96
https://pubmed.ncbi.nlm.nih.gov/32900346
https://pubmed.ncbi.nlm.nih.gov/32900346
Autor:
Boniek G. Vaz, Germán Sanz, Adriane Ferreira de Brito, Luciano M. Lião, Ianca Gontijo Cavalcante Santana, Carina Sofia Cardoso, Daiany Priscilla Bueno da Silva, Danillo Ramos de Oliveira, Fábio Fagundes da Rocha, Elson Alves Costa, Pablinny Moreira Galdino, Flávio Silva de Carvalho, Dayane Moreira da Silva, Lorrane Kelle da Silva Moreira, Ricardo Menegatti
Publikováno v:
Biomedicine & Pharmacotherapy. 103:546-552
The piperazine derivatives correspond to an extensive chemical class of compounds with numerous neuropharmacological activities, including antidepressant (e.g., nefazodone, trazodone) and anxiolytic (e.g., buspirone) properties. Therefore, aiming to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50572f071fd564fd16733948c640f71c
https://doi.org/10.1016/j.biopha.2018.04.077
https://doi.org/10.1016/j.biopha.2018.04.077
Autor:
Ricardo J. Alves de Sousa, António B. Pereira, Fábio A. O. Fernandes, Pedro Marques, Fábio Fagundes da Rocha, Ana Cabrinha
Publikováno v:
Metals
Volume 9
Issue 1
Metals, Vol 9, Iss 1, p 102 (2019)
Volume 9
Issue 1
Metals, Vol 9, Iss 1, p 102 (2019)
The welding of dissimilar metals was carried out using a pulsed Nd: YAG laser to join DP1000 steel and an aluminum alloy 1050 H111. Two sheets of each metal, with 30 ×
14 ×
1 mm3, were lap welded, since butt welding proved to be n
14 ×
1 mm3, were lap welded, since butt welding proved to be n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849863e2571fe99d933ae89233d1910c
Autor:
Pablinny Moreira Galdino, Danillo Ramos de Oliveira, Ricardo Menegatti, James Oluwagbamigbe Fajemiroye, Marize Campos Valadares, Iziara Ferreira Florentino, Fábio Fagundes da Rocha, Thereza Christina Monteiro de Lima, Soraia Santana de Moura, Elson Alves Costa
Publikováno v:
Life Sciences. 143:187-193
Aims Piperazinic derivatives have therapeutic potential by acting as analgesic, antidepressant-like, anticonvulsant and antipsychotic in preclinical studies. In order to develop new drugs to treat mental disorders, we designed and synthesized the 4-(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f5f6feb4550a6eb3ea2c4b5d742cc0a
https://doi.org/10.1016/j.lfs.2015.11.009
https://doi.org/10.1016/j.lfs.2015.11.009
Autor:
Germán Sanz, Boniek G. Vaz, Crisciele Fontana, Elson Alves Costa, Fábio Fagundes da Rocha, Luciano M. Lião, Ricardo Menegatti, Hugo Verli, Adriane Ferreira de Brito, Lorrane Kelle da Silva Moreira, Flávio Souza de Carvalho
Publikováno v:
Behavioural Brain Research. 394:112827
Piperazine derivatives are an attractive class of chemical compounds for the treatment of various mental illness. Herein, we demonstrated the synthesis of LQFM212, a piperazine derivative, behavioral evaluation in mice and computational studies. In n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36f4a771992025979da85269a07e986
https://doi.org/10.1016/j.bbr.2020.112827
https://doi.org/10.1016/j.bbr.2020.112827
Autor:
Guinever E. Imperio, Claudio Silva-Almeida, Roberto Laureano-Melo, Fábio Fagundes da Rocha, Tania M. Ortiga-Carvalho, Wellington da Silva Côrtes, Anderson Luiz Bezerra da Silveira, George Eduardo Gabriel Kluck, Luís Carlos Reis, Fernando A.C. Seara
Publikováno v:
Pharmacology Biochemistry and Behavior. 138:123-132
Selenium is a micronutrient which is part of selenoprotein molecules and participates in a vast number of physiological roles and, among them,we have fetal and neonatal development. Therefore, the aimof this studywas to evaluate possible behavioral c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb384c3542169ec8c9ea51a23b5662ea
https://doi.org/10.1016/j.pbb.2015.09.007
https://doi.org/10.1016/j.pbb.2015.09.007
Autor:
Elson Alves Costa, Iziara Ferreira Florentino, Pablinny Moreira Galdino, Fábio Fagundes da Rocha, Daiany Priscilla Bueno da Silva, Dayane Moreira da Silva, James Oluwagbamigbe Fajemiroye, Adriane Ferreira de Brito, Danillo Ramos de Oliveira
Publikováno v:
CNSneurological disorders drug targets. 17(4)
Background: Major depressive disorder is a psychiatric disorder that affects 4.4% of the population worldwide. Although the majority of antidepressant drugs ameliorate depressive symptoms, there is still a need for safer and more effective antidepres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb047c977429e30c56ce8b15aaa69fd
https://pubmed.ncbi.nlm.nih.gov/29676236
https://pubmed.ncbi.nlm.nih.gov/29676236
Autor:
Iziara Ferreira Florentino, Pablinny Moreira Galdino, Jordan K. Zjawiony, James Oluwagbamigbe Fajemiroye, Fábio Fagundes da Rocha, PR Polepally, Elson Alves Costa, Paulo César Ghedini
Publikováno v:
Journal of Psychopharmacology. 28:923-934
Our study sought to evaluate the anxiolytic and antidepressant activities of oleanolic acid as well as the neural mechanisms involved. Animal models such as barbiturate sleep-induction, light–dark box, elevated plus maze, forced swimming test, tail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097ddcb4c1ebe754ef4df9904b2ab972
https://doi.org/10.1177/0269881114536789
https://doi.org/10.1177/0269881114536789