Sequencing of human genomes extracted from single cancer cells isolated in a valveless microfluidic device

Autor: Loïc Baerlocher, Kalim U. Mir, Kamila Koprowska, Neil Ashley, Julien Schira, Niels Agersnap, Rodolphe Marie, Roland C. M. Vulders, Brian Bilenberg, Marie Pødenphant, F van Hemert, Celine Sabatel, Dianne Arnoldina Margaretha Wilhelmina Van Strijp, P. J. van der Zaag, Walter F. Bodmer, Jennifer L. Wilding, Tom Olesen, Simon J. McGowan, Anders Kristensen

Publikováno v: Marie, R, Pødenphant, M, Koprowska, K, Baerlocher, L, Vulders, R C M, Wilding, J, Ashley, N, McGowan, S J, van Strijp, D, van Hemert, F, Olesen, T, Agersnap, N, Bilenberg, B, Sabatel, C, Schira, J, Kristensen, A, Bodmer, W, van der Zaag, P J & Mir, K U 2018, ' Sequencing of human genomes extracted from single cancer cells isolated in a valveless microfluidic device ', Lab on a Chip, vol. 18, no. 13, pp. 1891-1902 . https://doi.org/10.1039/c8lc00169c

Sequencing the genomes of individual cells enables the direct determination of genetic heterogeneity amongst cells within a population. We have developed an injection-moulded valveless microfluidic device in which single cells from colorectal cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7e6691a030b9d8c90184143e704672
https://ora.ox.ac.uk/objects/uuid:f2d51e3c-1414-41b8-8d0f-f0639fb81122

Transmission characteristics and optimal diagnostic samples to detect an FMDV infection in vaccinated and non-vaccinated sheep

Autor: P.L. Eblé, F. van Hemert-Kluitenberg, Aldo Dekker, Karin Orsel

Publikováno v: Veterinary Microbiology 177 (2015) 1-2
Veterinary Microbiology, 177(1-2), 69-77

We wanted to quantify transmission of FMDV Asia-1 in sheep and to evaluate which samples would be optimal for detection of an FMDV infection in sheep. For this, we used 6 groups of 4 non-vaccinated and 6 groups of 4 vaccinated sheep. In each group 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b32acba20682fe1787991b4af4a50f67
https://doi.org/10.1016/j.vetmic.2015.02.012

Comparison of immune responses after intra-typic heterologous and homologous vaccination against foot-and-mouth disease virus infection in pigs

Autor: P.L. Eblé, F. van Hemert-Kluitenberg, Annemarie Bouma, Aldo Dekker, M. de Bruin

Publikováno v: Vaccine 24 (2006) 9
Vaccine, 24(9), 1274-1281

This study compares the immune responses and protection induced by intra-typic heterologous vaccination with that induced by homologous vaccination against challenge with foot-and-mouth disease virus (FMDV). Humoral and cell-mediated immune responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82c8b957e03cdebb631f52ec739e07a
https://doi.org/10.1016/j.vaccine.2005.09.040

Vaccination of pigs two weeks before infection significantly reduces transmission of foot-and-mouth disease virus

Autor: Annemarie Bouma, M. de Bruin, J.T. van Oirschot, Aldo Dekker, F. van Hemert-Kluitenberg, P.L. Eblé

Publikováno v: Vaccine, 22(11-12), 1372-1378
Vaccine 22 (2004) 11-12

The objective of this study was to investigate whether and at what time interval could vaccination reduce transmission of foot-and-Mouth disease virus (FMDV) among pigs. Reduction of virus transmission by vaccination was determined experimentally. Tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb6dfd837c54362306db614dd737525
https://research.wur.nl/en/publications/vaccination-of-pigs-two-weeks-before-infection-significantly-redu

Isotype specific ELISAs to detect antibodies against swine vesicular disease virus and their use in epidemiology

Autor: C. Terpstra, F. Van Hemert-Kluitenberg, C. Baars, Aldo Dekker

Publikováno v: Epidemiology and Infection, 128(2), 277-284
Epidemiology and Infection 128 (2002) 2

Isotype specific ELISAs to detect antibodies against swine vesicular disease, which may help to estimate the moment of infection, were developed and validated on sera from pigs experimentally infected with four different isolates of swine vesicular d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aab08ab2266dd2444d1c35e21254825
https://europepmc.org/articles/PMC2869821/