Zobrazeno 1 - 10
of 15
pro vyhledávání: '"F, phenylalanine"'
Amino acid residue at the 165th position tunes EYFP chromophore maturation. A structure-based design
Autor:
Vladimir Z. Pletnev, Eugene G. Maksimov, Anastasia V. Mamontova, Elena A. Protasova, Rustam H. Ziganshin, Konstantin A. Lukyanov, Nadya V. Pletneva, Sergei Pletnev, Tatiana R. Simonyan, Liya Muslinkina, Alexey M. Bogdanov
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2950-2959 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2950-2959 (2021)
Graphical abstract
For the whole GFP family, a few cases, when a single mutation in the chromophore environment strongly inhibits maturation, were described. Here we study EYFP-F165G – a variant of the enhanced yellow fluorescent protein – o
For the whole GFP family, a few cases, when a single mutation in the chromophore environment strongly inhibits maturation, were described. Here we study EYFP-F165G – a variant of the enhanced yellow fluorescent protein – o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86d1191f9c8ae5e9ff3d8772e885cc6
http://europepmc.org/articles/PMC8163865
http://europepmc.org/articles/PMC8163865
Autor:
Ran Chen, Zhi Yang, Hailong Zhang, Yanli Wang, Shengfang Ge, Jianxiu Yu, Tianqi Liu, Jiayu Fang, Jian Huang, Xian Zhao
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 3, Pp 129-141 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Numerous studies have reported that c-Src is highly expressed with high tyrosine kinase activity in a variety of tumors. However, it remains unclear whether c-Src contributes to the miRNA pathway. Here, we report that c-Src can interact with and phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c464bc31bf758ee159108f52b67cb982
http://www.sciencedirect.com/science/article/pii/S1476558619303914
http://www.sciencedirect.com/science/article/pii/S1476558619303914
Autor:
Enoch, Aninagyei, Comfort Dede, Tetteh, Martin, Oppong, Alex, Boye, Desmond Omane, Acheampong
Publikováno v:
Parasite Epidemiology and Control
Introduction Artemether-Lumefantrine (A-L) remains the drug of choice for the treatment of uncomplicated malaria in Ghana. However, the pharmaco-activity of A-L has not been assessed on various Plasmodium falciparum Kelch 13 and Pfmdr1 genes. Therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1fa85b06cdb2f627dd7f876606012203
https://pubmed.ncbi.nlm.nih.gov/33163636
https://pubmed.ncbi.nlm.nih.gov/33163636
Publikováno v:
Toxicology Reports, Vol 5, Iss, Pp 552-560 (2018)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Common bean protein fractions decreased glucose uptake in colorectal cancer cells. • Protein fractions decreased SGLT1 and GLUT2 gene and protein expression and translocation. • Black bean protein fractions
Highlights • Common bean protein fractions decreased glucose uptake in colorectal cancer cells. • Protein fractions decreased SGLT1 and GLUT2 gene and protein expression and translocation. • Black bean protein fractions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ac39f976b2d21eed48dfab230775d1
http://www.sciencedirect.com/science/article/pii/S2214750018303081
http://www.sciencedirect.com/science/article/pii/S2214750018303081
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 752-763 (2014)
Toxicology Reports
Toxicology Reports
Highlights • CS downregulates Lat1, transporter of leucine, in alveolar epithelial cells. • Lat1 downregulation leads to mTOR inactivation and cell death in A549. • Dietary leucine supplementation prevents CS-induced mTOR inactivation in animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95042f07e7df346d1c2937f997de7b11
Akademický článek
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Publikováno v:
FEBS Open Bio
Under normal conditions histone H2AX is constitutively phosphorylated on tyrosine (Y) 142 by Williams–Beuren syndrome transcription factor kinase (WSTF). Following DNA double strand breaks (DSB), Y142 is de-phosphorylated and serine (S) 139 is phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb989a19ea9ccbd760b5c227b816bb94
Autor:
Pletneva NV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117997, Russia., Maksimov EG; Faculty of Biology, Lomonosov Moscow State University, 119992 Moscow, Russia., Protasova EA; Faculty of Biology, Lomonosov Moscow State University, 119992 Moscow, Russia., Mamontova AV; Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow 121205, Russia., Simonyan TR; Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow 121205, Russia., Ziganshin RH; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117997, Russia., Lukyanov KA; Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow 121205, Russia., Muslinkina L; Structural Biology Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Pletnev S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Bogdanov AM; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117997, Russia., Pletnev VZ; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117997, Russia.
Publikováno v:
Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2021 May 11; Vol. 19, pp. 2950-2959. Date of Electronic Publication: 2021 May 11 (Print Publication: 2021).
Autor:
Aninagyei E; University of Health and Allied Sciences, School of Basic and Biomedical Sciences, Department of Biomedical Sciences, PMB 31, Ho-Volta Region, Ghana., Tetteh CD; Ghana Health Service, Municipal Health Directorate, Ga West Municipal, Amasaman, Ghana., Oppong M; Ghana Health Service, Municipal Health Directorate, Ga West Municipal, Amasaman, Ghana., Boye A; University of Cape Coast, School of Allied Health Sciences, Department of Medical Laboratory Science, Cape Coast, Ghana., Acheampong DO; University of Cape Coast, School of Allied Health Sciences, Department of Biomedical Sciences, Cape Coast, Ghana.
Publikováno v:
Parasite epidemiology and control [Parasite Epidemiol Control] 2020 Oct 26; Vol. 11, pp. e00190. Date of Electronic Publication: 2020 Oct 26 (Print Publication: 2020).
Publikováno v:
Journal of neurosurgery [J Neurosurg] 2018 May; Vol. 128 (5), pp. 1419-1427. Date of Electronic Publication: 2017 Jul 28.