Zobrazeno 1 - 10
of 328
pro vyhledávání: '"F, de Sauvage"'
Autor:
Sergey Nikolaev, Nicolas Dumaz, A. Alberti, M. Delord, Nicole Basset-Seguin, Andrey A. Yurchenko, O. Tiberiu Pop, Hayley J. Sharpe, Meriem Ighilahriz, F. de Sauvage
Publikováno v:
Annales de Dermatologie et de Vénéréologie. 147:A15
Les inhibiteurs de la voie Hedgehog (5Hh) ont transforme le devenir des patients atteints de CBC avances (CBCla). La majorite des patients sont repondeurs, mais une faible proportion sont resistants primaires (RP) et les mecanismes de cette resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d38b3f04b27725058e9f78798a1678c9
https://doi.org/10.1016/j.annder.2020.08.013
https://doi.org/10.1016/j.annder.2020.08.013
Akademický článek
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Autor:
Minwook Kim1,2, Yoojeong Park1,2, You Sun Kim1,3 yousunk69@korea.com, Sungjin Ko1,2 sungjin@pitt.edu
Publikováno v:
Gut & Liver. Nov2024, Vol. 18 Issue 6, p949-960. 12p.
Autor:
Audrey Letourneau, Nicole Basset-Seguin, F. de Sauvage, C. Verdan, Martin Eilers, Pascale Ribaux, Olga Sumara, Olivier Michielin, Maria A. Andrianova, Bryan W. King, Iannis Aifantis, Thomas Alexander Mckee, Vincent Zoete, Michel Guipponi, Sergey Nikolaev, Hayley J. Sharpe, Fedor Bezrukov, Laurent Parmentier, Stylianos E. Antonarakis, Marco Garieri, Ximena Bonilla, R. Ben Chaabene, K. Grosdemange, Federico Santoni, Vladimir B. Seplyarskiy, Gürkan Kaya, K. Papodin
Publikováno v:
Annales de Dermatologie et de Vénéréologie. 143:S185-S186
Introduction Les carcinomes basocellulaires (BCC) sont les cancers cutanes les plus frequents chez l’homme. Leur determinisme est lie a l’activation de la voie hedgehog, qui est actuellement la cible d’inhibiteurs specifiques. Neanmoins, l’im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6cb21e5e14f70e6b2df8bb31bd567d8
https://doi.org/10.1016/j.annder.2016.09.221
https://doi.org/10.1016/j.annder.2016.09.221
Autor:
J. Ziniti, F. de Sauvage, Chäng Sim, Mark C. Fishman, D. Jackson, N. Shimoda, S. Kaplan, Howard J. Jacob, E. Yamada, Ela W. Knapik
Publikováno v:
Genomics. 58:219-232
The zebrafish is the first vertebrate organism used for large-scale genetic screens seeking genes critical to development. These screens have been quite successful, with more than 1800 recessive mutations discovered that speak to morphogenesis of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b108d7e8c579a47364c3614ee8f0001f
https://doi.org/10.1006/geno.1999.5824
https://doi.org/10.1006/geno.1999.5824
Autor:
Mark W. Moore, Karen Carver-Moore, Eric Stefanich, M Marian, F. de Sauvage, Paul J. Fielder, AL Gurney
Publikováno v:
Blood. 87:2154-2161
The involvement of platelets and the c-mpl receptor in the regulation of thrombopoietin (TPO) plasma concentrations and tissue mRNA levels was investigated in both normal mice and mice defective in c-mpl (c-mpl-’-). Although cmpl-‘- mice have few
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd466552660744eb87fb9d739f15289
https://doi.org/10.1182/blood.v87.6.2154.bloodjournal8762154
https://doi.org/10.1182/blood.v87.6.2154.bloodjournal8762154
Publikováno v:
Proceedings of the National Academy of Sciences. 92:5292-5296
c-Mpl, a member of the hematopoietic cytokine receptor family, is the receptor for thrombopoietin. To investigate signal transduction by c-Mpl, a chimeric receptor, composed of the extracellular domain of human growth hormone receptor and the intrace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e035e846f3da2aec1fdf86fc179e59e
https://doi.org/10.1073/pnas.92.12.5292
https://doi.org/10.1073/pnas.92.12.5292
Publikováno v:
Blood. 85:981-988
Thrombopoietin (TPO), the ligand for c-mpl, is a novel cytokine comprising an amino terminal domain with homology to erythropoietin and a glycosylated carboxyl terminal domain that does not bear overall homology to other known proteins. We report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a20b637365e446d8156a89454cab1300
https://doi.org/10.1182/blood.v85.4.981.bloodjournal854981
https://doi.org/10.1182/blood.v85.4.981.bloodjournal854981
Autor:
Philip E. Hass, Christopher J. Donahue, F. de Sauvage, Francis C. Zeigler, William Matthews, HR Widmer, RD Schreiber, B. E. Malloy, Dan L. Eaton, Gilbert-Andre Keller
Publikováno v:
Blood. 84:4045-4052
Recently, the ligand for c-mpl has been identified and cloned. Initial studies of this molecule indicate that it is the platelet regulatory factor, thrombopoietin (TPO). Previous work has indicated that c-mpl is expressed in very immature hematopoiet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bee907d091888c38eab9fffbca521eea
https://doi.org/10.1182/blood.v84.12.4045.bloodjournal84124045
https://doi.org/10.1182/blood.v84.12.4045.bloodjournal84124045
Publikováno v:
Journal of Biological Chemistry. 268:22397-22401
Guanylin is a 15-amino acid peptide hormone that was originally isolated from the jejunum of the rat small intestine and shown to be an endogenous activator of the intestinal heat-stable enterotoxin receptor-guanylyl cyclase. Guanylin is synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b20e6ad99b6c0cc9ec9fce80d4638d1
https://doi.org/10.1016/s0021-9258(18)41542-6
https://doi.org/10.1016/s0021-9258(18)41542-6