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Differentiation of Caco-2 cells requires both transcriptional and post-translational down-regulation of Myc

Autor: Barbara Bucci, Armando Felsani, Igea D'Agnano, Marta Nardella, F. Zucco, Bruno D. Leoni, Manuela Natoli

Publikováno v: Differentiation (Lond.) 83 (2012): 116–127. doi:10.1016/j.diff.2011.10.005
info:cnr-pdr/source/autori:Leoni Bruno Daniele a; Natoli Manuela a; Nardella Marta a; Bucci Barbara c; Zucco Flavia a; D'Agnano Igea a,b; Felsani Armando a,b/titolo:Differentiation of Caco-2 cells requires both transcriptional and post-translational down-regulation of Myc/doi:10.1016%2Fj.diff.2011.10.005/rivista:Differentiation (Lond.)/anno:2012/pagina_da:116/pagina_a:127/intervallo_pagine:116–127/volume:83

Caco-2 cancer cell line is widely used to reproduce in vitro the differentiation of absorptive enterocytes of human intestinal epithelium. This cell line, when cultured over confluence for 21 days, spontaneously undergoes cell cycle arrest and differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f605598063f50483ffc4abd3fa3793d4
https://doi.org/10.1016/j.diff.2011.10.005

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The management of constipation in palliative care: clinical practice recommendations

Autor: Maria Nabal, Philip Larkin, Carla Ripamonti, Wouter W.A. Zuurmond, Frank Elsner, Carlos Centeno, J.R.G. Gootjes, Antonio Noguera, Nigel Sykes, B. Eugene, John Ellershaw, F Zucco

Publikováno v: Palliative Medicine, 22(7), 796-807. SAGE Publications Ltd
Larkin, J, Sykes, N P, Centeno, C, Ellershaw, J E, Elsner, F, Eugene, B, Gootjes, J R G, Nabal, M, Noguera, A, Ripamonti, C, Zuco, F & Zuurmond, W W A 2009, ' The management of constipation in palliative care: clinical practice recommendations ', Medicina Paliativa, vol. 16, no. 3, pp. 164-177 .
Larkin, P J, Sykes, N P, Centeno, C, Ellershaw, J E, Elsner, F, Eugene, B, Gootjes, J R, Nabal, M, Noguera, A, Ripamonti, C, Zucco, F & Zuurmond, W W A 2008, ' The management of constipation in palliative care: clinical practice recommendations ', Palliative Medicine, vol. 22, no. 7, pp. 796-807 . https://doi.org/10.1177/0269216308096908
Medicina Paliativa, 16(3), 164-177. Elsevier Doyma

Constipation is one of the most common problems in patients receiving palliative care and can cause extreme suffering and discomfort. The aims of this study are to raise awareness of constipation in palliative care, provide clear, practical guidance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da856cbdb9f5e868b9de1ffb1ac09d3b
https://doi.org/10.1177/0269216308096908

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Pain management in Internal Medicine and effects of a standardised educational intervention: The FADOI-DOMINO Study

Autor: G, Civardi, F, Zucco, A, Valerio, A, Fontanella, M, Alessandri, C D, Ciannamea, L, Perale, G, Gussoni, E, Bonizzoni, G, Vescovo, G, Agnelli, M, Campanini, A, Mazzone, C, Nozzoli, F, Gallucci

Summary Purpose Few real-world data are available on the frequency and management of pain in Internal Medicine (IM). Aims of our study were to assess the prevalence of pain in IM, and to evaluate the effects on pain management of a standardised educa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff88df2e35f5778ed87c057e03ee6bfa
http://hdl.handle.net/11391/1434374

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Absorption of Fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein

Autor: F. Raimondi, I. De Angelis, G. Friggè, Annalaura Stammati, F. Zucco, Francesca Caloni

Publikováno v: Toxicon (Oxf.) 45 (2005): 285–291.
info:cnr-pdr/source/autori:De Angelis I.1, Friggè G.2, Raimondi F.3, Stammati A.4, Zucco F.5, Caloni F.6/titolo:Absorption of fumonisin B1 and aminopentol on an in vitro model of intestinal epithelium; the role of P-glycoprotein./doi:/rivista:Toxicon (Oxf.)/anno:2005/pagina_da:285/pagina_a:291/intervallo_pagine:285–291/volume:45

The aim of the present paper is to evaluate the absorption of fumonisin B1 and its principal metabolite, aminopentol on a human intestinal model, Caco-2 cells, cultured on semi-permeable inserts, that reproduces the two different intestinal compartme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d710cb99ea643c823aeac3dba0f1f81
https://doi.org/10.1016/j.toxicon.2004.10.015

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[Untitled]

Autor: F. Zucco, L. Turco, I. De Angelis, Annalaura Stammati

Publikováno v: Cell Biology and Toxicology. 16:53-62

The recent increase in understanding of cell death has promoted new approaches in toxicological studies, mainly those dealing with in vitro systems where the evaluation of cell death has been the most widely adopted end-point in measuring the effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::466cfd47629ec50c99f9511a3ec87777
https://doi.org/10.1023/a:1007696604725

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A contribution to safety assessment of veterinary drug residues: in vitro / ex vivo studies on the intestinal toxicity and transport of covalently bound residues

Autor: S. Klee, F. R. Ungemach, A. Stammati, I. Baumung, A. L. Vignoli, M. O'keeffe, K. Kluge, E. Horne, F. Zucco, I. De Angelis

Publikováno v: Xenobiotica. 29:641-654

1. The gastrointestinal fate of protein-bound residues of the model compound furazolidone (FZD) was investigated in vitro and ex vivo. Protein-bound residues were generated in rat liver microsomes, isolated by solvent extraction and digested with 0.5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddaf0d5452938bf1e8b19862815e3ed0
https://doi.org/10.1080/004982599238452

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Toxicity of selected plant volatiles in microbial and mammalian short-term assays

Autor: A. Stammati, P. Bonsi, F. Zucco, R. Moezelaar, H.-L. Alakomi, A. von Wright

Publikováno v: Food and Chemical Toxicology 37 (1999) 8
Stammati, A, Bonsi, P, Zucco, F, Moezelaar, R, Alakomi, H-L & Wright, A V 1999, ' Toxicity of selected plant volatiles in microbial and mammalian short-term assays ', Food and Chemical Toxicology, vol. 37, no. 8, pp. 813-823 . https://doi.org/10.1016/S0278-6915(99)00075-7
Food and Chemical Toxicology, 37(8), 813-823

In this study, several short-term microbial and mammalian in vitro assays were used to evaluate cytotoxicity and genotoxicity of four plant volatiles showing antifungal activity: cinnamaldehyde, carvacrol, thymol and S(+)-carvone. All inhibited viabi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a4868aa376c803c9303eaa82adf640
https://doi.org/10.1016/S0278-6915(99)00075-7

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Cytotoxicity of halogenated benzenes and its relationship with logP

Autor: S. Marchini, F. Zucco, Orazio Sapora, G. Fratello, Annalaura Stammati

Publikováno v: Toxicology in Vitro. 11:673-677

The in vitro toxicity of a series of environmentally relevant halobenzenes was tested using a Chinese hamster lung fibroblast cell line and its relationship with the logarithm of octanol/water partition coefficient (logP) was investigated. Since we w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8e09b8fe9d4165aeac68107e498b45
https://doi.org/10.1016/s0887-2333(97)00086-6

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Furaltadone cytotoxicity on three cell lines in the presence or absence of DMSO: Comparison with furazolidone

Autor: F. Zucco, Annalaura Stammati, F. Zampaglioni

Publikováno v: Cell Biology and Toxicology. 13:125-130

Nitrofuran drugs have been studied on cellular systems in order to develop in vitro tests for safety assessment of food contaminants. In the present study we have tested furaltadone on three cell lines (HEp-2, Caco-2 and V79), using the same toxicity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff320d8b02ac2e3c9b15e1a375c0c8c
https://doi.org/10.1023/b:cbto.0000010397.26120.4d

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