Zobrazeno 1 - 10
of 6 154
pro vyhledávání: '"F, Zhong"'
Publikováno v:
Patterns, Vol 5, Iss 5, Pp 100969- (2024)
Summary: Understanding the cellular composition of a disease-related tissue is important in disease diagnosis, prognosis, and downstream treatment. Recent advances in single-cell RNA-sequencing (scRNA-seq) technique have allowed the measurement of ge
Externí odkaz:
https://doaj.org/article/24cc7682458a499784d6ecac5eb0dec0
Autor:
Andres Stucky PhD, Chi T. Viet DDS, MD, PhD, Bradley E. Aouizerat PhD, Yi Ye PhD, Coleen Doan MD, Tarun Mundluru PhD, Parish Sedhiazadeh MD, Uttam K. Sinha MD, Xuelian Chen MD, Xi Zhang MD, PhD, Shengwen Calvin Li PhD, Jin Cai MD, Jiang F. Zhong PhD
Publikováno v:
Cancer Control, Vol 31 (2024)
Objectives To determine the dysregulated signaling pathways of head and neck squamous cell carcinoma associated with circulating tumor cells (CTCs) via single-cell molecular characterization. Introduction Head and neck squamous cell carcinoma (HNSCC)
Externí odkaz:
https://doaj.org/article/b9059099fe424cca9235e3beadc240a9
Publikováno v:
Hydrology and Earth System Sciences, Vol 26, Pp 6399-6412 (2022)
Although evidence of the hydrological response of watersheds to climate change is abundant, reliable assessments of water yield (WY) over mountainous regions, such as the Upper Brahmaputra River (UBR) basin, remain unclear. Here, we examine long-term
Externí odkaz:
https://doaj.org/article/6ffbe3e2dd6b45849f46a15717893a7a
Publikováno v:
Hydrology and Earth System Sciences, Vol 26, Pp 5647-5667 (2022)
Rainfall interception loss remains one of the most uncertain fluxes in the global water balance, hindering water management in forested regions and precluding an accurate formulation in climate models. Here, a synthesis of interception loss data from
Externí odkaz:
https://doaj.org/article/81d8cd47253a4e3fae03d404ad6853eb
Autor:
Yi Xu, Christopher Hino, David J. Baylink, Jeffrey Xiao, Mark E. Reeves, Jiang F. Zhong, Saied Mirshahidi, Huynh Cao
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-5 (2022)
Abstract Acute myeloid leukemia (AML) has the lowest survival rate among the leukemias. Targeting intracellular metabolism and energy production in leukemic cells can be a promising therapeutic strategy for AML. Recently, we presented the successful
Externí odkaz:
https://doaj.org/article/f736b737ff18458391da2cc5d0a70964
Autor:
Chi T. Viet, Xinyu Zhang, Ke Xu, Gary Yu, Kesava Asam, Carissa M. Thomas, Nicholas F. Callahan, Coleen Doan, Paul C. Walker, Khanh Nguyen, Stephanie C. Kidd, Steve C. Lee, Anupama Grandhi, Clint T. Allen, Simon Young, James C. Melville, Jonathan W. Shum, Dan T. Viet, Alan S. Herford, Dylan F. Roden, Manuel L. Gonzalez, Jiang F. Zhong, Bradley E. Aouizerat
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-10 (2021)
Abstract Background Oral squamous cell carcinoma (OSCC) has poor survival rates. There is a pressing need to develop more precise risk assessment methods to tailor clinical treatment. Epigenome-wide association studies in OSCC have not produced a via
Externí odkaz:
https://doaj.org/article/260f7bc1d90040bebd27e0254089dfb3
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-21 (2021)
Abstract Long-read RNA sequencing (RNA-seq) technologies can sequence full-length transcripts, facilitating the exploration of isoform-specific gene expression over short-read RNA-seq. We present LIQA to quantify isoform expression and detect differe
Externí odkaz:
https://doaj.org/article/951d188b89294a539bbd33d031d8edd2
Publikováno v:
BMC Genomics, Vol 21, Iss S11, Pp 1-12 (2020)
Abstract Background Long-read RNA-Seq techniques can generate reads that encompass a large proportion or the entire mRNA/cDNA molecules, so they are expected to address inherited limitations of short-read RNA-Seq techniques that typically generate
Externí odkaz:
https://doaj.org/article/1a9447ebbaeb49dfb273f2113cfbbc96
Autor:
Andres Stucky, Li Gao, Shengwen Calvin Li, Lingli Tu, Jun Luo, Xi Huang, Xuelian Chen, Xiaoqing Li, Tiffany H. Park, Jin Cai, Mustafa H. Kabeer, Ashley S. Plant, Lan Sun, Xi Zhang, Jiang F. Zhong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: The mechanism of tumorigenicity potentially evolved in mesenchymal stem cells (MSCs) remains elusive, resulting in inconsistent clinical application efficacy. We hypothesized that subclones in MSCs contribute to their tumorgenicity, and w
Externí odkaz:
https://doaj.org/article/6c78a0d42c994f4fa376bb4667cf911f
Autor:
Ruihao Huang, Xiaoping Li, Yundi He, Wen Zhu, Lei Gao, Yao Liu, Li Gao, Qin Wen, Jiang F. Zhong, Cheng Zhang, Xi Zhang
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-19 (2020)
Abstract Chimeric antigen receptor T (CAR-T) cell therapy is regarded as an effective solution for relapsed or refractory tumors, particularly for hematological malignancies. Although the initially approved anti-CD19 CAR-T therapy has produced impres
Externí odkaz:
https://doaj.org/article/e63d904f3d1b45e0a7f5550fb95e543c