Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRβ-HOXA rearrangement: a study of the Groupe Francophone de Cytogénétique Hématologique

Autor: C. Charrin, Anne Hagemeijer, Carole Barin, M J Mozzicconacci, Barbara Cauwelier, Christine Lefebvre, Bruno Verhasselt, Isabelle Luquet, M.J. Gregoire, Philippe Jonveaux, Hélène Cavé, Barbara De Moerloose, Christine Terré, Kim De Keersmaecker, Anne De Paepe, G Plessis, F Sigaux, Nicole Dastugue, Bruce Poppe, Michel Lessard, B Laurence, Laurent Mauvieux, Hélène Antoine-Poirel, Marina Lafage-Pochitaloff, Francine Mugneret, Emmanuelle Clappier, J van den Akker, J Soulier, C Graux, Yves Benoit, Jan Cools, Carine Gervais, Franki Speleman, Pascale Cornillet-Lefebvre, Marie-Pierre Pages, C Chalas, Dominique Leroux, N. Van Roy, Christine Perot, Pierre Heimann, Roland Berger

Publikováno v: Leukemia
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2007, 21 (1), pp.121-8. ⟨10.1038/sj.leu.2404410⟩
Leukemia, 2007, 21 (1), pp.121-8. ⟨10.1038/sj.leu.2404410⟩
Leukemia, Nature Publishing Group: Open Access Hybrid Model Option B, 2007, 21 (1), pp.121-8. <10.1038/sj.leu.2404410>

International audience; Recently, we and others described a new chromosomal rearrangement, that is, inv(7)(p15q34) and t(7;7)(p15;q34) involving the T-cell receptor beta (TCRbeta) (7q34) and the HOXA gene locus (7p15) in 5% of T-cell acute lymphoblas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0e2a8fa5b81d3b8f190bc9464a5df5
https://doi.org/10.1038/sj.leu.2404410

Aplastic anemia and paroxysmal nocturnal hemoglobinuria: a follow-up study of the glycosylphosphatidylinositol-anchored proteins defect

Autor: Maria-Elena Noguera, Gluckman E, Bittencourt E, Gérard Socié, Leymarie, F Sigaux

Publikováno v: The Hematology Journal. 1:250-253

Introduction: Flow cytometry analysis of peripheral blood cells is a simple and reliable method for establishing the diagnosis of paroxysmal nocturnal hemoglobinuria. The behavior of the clone may vary; increasing or diminishing over time but prospec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8628d5ee84d3cf2adc90cbe0b7f669d4
https://doi.org/10.1038/sj.thj.6200035

Cutting Edge: Requirement of Class I Signal Sequence-Derived Peptides for HLA-E Recognition by a Mouse Cytotoxic T Cell Clone

Autor: S, Martinozzi, R, Pacasova, H J, Boulouis, M, Ulbrecht, E H, Weiss, F, Sigaux, M, Pla

Publikováno v: The Journal of Immunology. 162:5662-5665

The human nonclassical MHC class I molecule HLA-E has recently been shown to act as a major ligand for NK cell inhibitory receptors. Using HLA-E-expressing transgenic mice, we produced a cytotoxic T cell clone that specifically recognizes the HLA-E m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d52071fb8e4a4758843fbb696e3871
https://doi.org/10.4049/jimmunol.162.10.5662

Influence of CD34 cell selection on the incidence of mixed chimaerism and minimal residual disease after allogeneic unrelated donor transplantation

Autor: Gérard Socié, Colette Raffoux, Eliane Gluckman, Helene Esperou, Brigitte Raynal, Nathalie Parquet, F Sigaux, Patricia Ribaud, Jean Michel Cayuela, Agnès Devergie, Jean-Pierre Marolleau, Xavier Fund, Olivier Brison

Publikováno v: Leukemia. 12:1440-1446

Marrow transplantation from unrelated donors has been linked with an increased risk of graft-versus-host disease (GVHD). In an attempt to lower the risk of acute GVHD we used CD34 marrow cell selection for T cell depletion. Since T cell depletion has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df9c98649d01d8390ae17c7ee6d9c50
https://doi.org/10.1038/sj.leu.2401110

Acquisition of granzyme B and Fas ligand proteins by human keratinocytes contributes to epidermal cell defense

Autor: C Berthou, L Michel, A Soulié, F Jean-Louis, B Flageul, L Dubertret, F Sigaux, Y Zhang, M Sasportes

Publikováno v: The Journal of Immunology. 159:5293-5300

In vertebrate tissues, cell integrity is maintained by at least three mechanisms. During an immune response, injured cells are eliminated by cytotoxic lymphoid cells that produce perforin, granzyme B, and Fas ligand (FasL). Second, epithelial cells c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::61b14d4c0124f3701b51d28e6e467008
https://doi.org/10.4049/jimmunol.159.11.5293