Zobrazeno 1 - 10
of 314
pro vyhledávání: '"F, Siepmann"'
Autor:
Y. Bedulho das Lages, N. Milanino, J. Verin, J.F. Willart, F. Danede, C. Vincent, P. Bawuah, J.A. Zeitler, F. Siepmann, J. Siepmann
Publikováno v:
International Journal of Pharmaceutics: X, Vol 8, Iss , Pp 100271- (2024)
This study evaluated the potential of poly(ethylene vinyl acetate) (EVA) copolymers as matrix formers in miniaturised implants, allowing to achieve controlled drug delivery into the inner ear. Due to the blood-cochlea barrier, it is impossible to rel
Externí odkaz:
https://doaj.org/article/e736761ac5e84a638d27e909f0f71710
Publikováno v:
International Journal of Pharmaceutics: X, Vol 7, Iss , Pp 100233- (2024)
Polysaccharides were identified, which allow for colon targeting in human Inflammatory Bowel Disease (IBD) patients, as well as in rats and dogs (which are frequently used as animals in preclinical studies). The polysaccharides are degraded by coloni
Externí odkaz:
https://doaj.org/article/743c8dcae609439785b9e4668375d98e
Autor:
L.A. Lefol, P. Bawuah, J.A. Zeitler, J. Verin, F. Danede, J.F. Willart, F. Siepmann, J. Siepmann
Publikováno v:
International Journal of Pharmaceutics: X, Vol 6, Iss , Pp 100220- (2023)
This study aimed to evaluate and better understand the potential impact that a layer of surrounding hydrogel (mimicking living tissue) can have on the drug release from PLGA microparticles. Ibuprofen-loaded microparticles were prepared with an emulsi
Externí odkaz:
https://doaj.org/article/8eab003d5b2b4d1682a8b314fd2498b0
Autor:
T. Rongthong, A. Qnouch, M. Maue Gehrke, F. Danede, J.F. Willart, P.F.M. de Oliveira, L. Paccou, G. Tourrel, P. Stahl, J. Verin, P. Toulemonde, C. Vincent, F. Siepmann, J. Siepmann
Publikováno v:
International Journal of Pharmaceutics: X, Vol 4, Iss , Pp 100141- (2022)
The aim of this study was to better understand the long term behavior of silicone-based cochlear implants loaded with dexamethasone: in vitro as well as in vivo (gerbils). This type of local controlled drug delivery systems offers an interesting pote
Externí odkaz:
https://doaj.org/article/4201b0b5d96c4c8ba2f4eedc7f1b5282
Publikováno v:
International Journal of Pharmaceutics: X, Vol 4, Iss , Pp 100131- (2022)
The aim of this study was to better understand the potential impact of partial vs. complete renewal of the bulk fluid during drug release measurements from poly (lactic-co-glycolic acid) (PLGA)-based implants. A “standard experimental set-up”, in
Externí odkaz:
https://doaj.org/article/07fdb73679b04890ba492924779bf1e8
Autor:
A. Qnouch, V. Solarczyk, J. Verin, G. Tourrel, P. Stahl, F. Danede, J.F. Willart, P.E. Lemesre, C. Vincent, J. Siepmann, F. Siepmann
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100088- (2021)
Cochlear implants containing iridium platinum electrodes are used to transmit electrical signals into the inner ear of patients suffering from severe or profound deafness without valuable benefit from conventional hearing aids. However, their placeme
Externí odkaz:
https://doaj.org/article/e6a0b79d86e945a38e1e9426b3e3273d
Autor:
C, Bassand, L, Benabed, S, Charlon, J, Verin, J, Freitag, F, Siepmann, J, Soulestin, J, Siepmann
Publikováno v:
Journal of Controlled Release
Journal of Controlled Release, 2022, Journal of Controlled Release, 353, pp.864-874. ⟨10.1016/j.jconrel.2022.11.052⟩
Journal of Controlled Release, 2022, Journal of Controlled Release, 353, pp.864-874. ⟨10.1016/j.jconrel.2022.11.052⟩
International audience; 3D Printing offers a considerable potential for personalized medicines. This is especially true for customized biodegradable implants, matching the specific needs of each patient. Poly(lactic-co-glycolic acid) (PLGA) is freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d37674478e6f76c6aba8b07b6d6bf54
https://doi.org/10.1016/j.jconrel.2022.11.052
https://doi.org/10.1016/j.jconrel.2022.11.052
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Publikováno v:
Journal of Controlled Release. 343:255-266
The aim of this study was to better understand to which extent and in which way the presence of an agarose gel (mimicking living tissue) around a PLGA [poly(lactic-co-glycolic acid)] implant affects the resulting drug release kinetics. Ibuprofen-load
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6181b379967ca1b37fabbe113731597e
https://doi.org/10.1016/j.jconrel.2022.01.028
https://doi.org/10.1016/j.jconrel.2022.01.028