Zobrazeno 1 - 10
of 250
pro vyhledávání: '"F, Shamji"'
Publikováno v:
Journal of Health Service Psychology. 48:175-184
Coronavirus 2019 (SARS-CoV-2; COVID-19) has significant mental health and neuropsychological consequences, but data are insufficient on these specific implications of COVID-19, especially for Indian American patients. Few studies have critically expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a603a6ea43e4856bff56c1eedf152b2e
https://doi.org/10.1007/s42843-022-00071-8
https://doi.org/10.1007/s42843-022-00071-8
Autor:
Elaine M. Oberlick, Matthew G. Rees, Brinton Seashore-Ludlow, Francisca Vazquez, Geoffrey M. Nelson, Neekesh V. Dharia, Barbara A. Weir, Aviad Tsherniak, Mahmoud Ghandi, John M. Krill-Burger, Robin M. Meyers, Xiaofeng Wang, Phil Montgomery, David E. Root, Jake M. Bieber, Sandi Radko, Jaime H. Cheah, C. Suk-Yee Hon, Alykhan F. Shamji, Paul A. Clemons, Peter J. Park, Michael A. Dyer, Todd R. Golub, Kimberly Stegmaier, William C. Hahn, Elizabeth A. Stewart, Stuart L. Schreiber, Charles W.M. Roberts
Publikováno v:
Cell Reports, Vol 28, Iss 9, Pp 2331-2344.e8 (2019)
Summary: Cancer is often seen as a disease of mutations and chromosomal abnormalities. However, some cancers, including pediatric rhabdoid tumors (RTs), lack recurrent alterations targetable by current drugs and need alternative, informed therapeutic
Externí odkaz:
https://doaj.org/article/92a087e67b0f487ba84b47b60011a6bf
Autor:
Stuart L. Schreiber, Paul A. Clemons, Alykhan F. Shamji, James E. Bradner, Michelle Palmer, Joshua A. Bittker, Vlado Dančík, Ted Liefeld, Benito Munoz, C. Suk-Yee Hon, Joanne D. Kotz, Nurdan Kuru, Mathias J. Wawer, Philip Montgomery, Ava Li, Benjamin Alexander, Joshua Gould, Christian K. Soule, Nicole E. Bodycombe, Victor Jones, Matthew E. Coletti, Edmund V. Price, Murat Cokol, Jaime H. Cheah, Matthew G. Rees, Brinton Seashore-Ludlow
Supplementary figure legends. Supplementary methods, including additional filtering and heuristics for sensitivity data processing and ACME analysis and additional methods for western blotting and immunostaining. Supplementary Table S8. Small molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c61698389d706f3e5ca7dcc783115de
https://doi.org/10.1158/2159-8290.22530798
https://doi.org/10.1158/2159-8290.22530798
Autor:
Sourav Bandyopadhyay, Andrei Goga, Frank McCormick, Kevan M. Shokat, Nevan J. Krogan, Stuart L. Schreiber, Alykhan F. Shamji, Paul A. Clemons, Jaime Cheah, Antonio Sorrentino, Mike Shales, John Jascur, Jeff Johnson, Rebecca S. Levin, John D. Gordan, Taha Rakhshandehroo, Christina Yau, Dai Horiuchi, Alexandra Corella, Alicia Y. Zhou, Maria M. Martins
Supplementary Table S2. Drugs and their concentrations used in the isogenic drug screen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ceecba2ea240f6046b9bdcfe401f9a2
https://doi.org/10.1158/2159-8290.22529895.v1
https://doi.org/10.1158/2159-8290.22529895.v1
Autor:
Stuart L. Schreiber, Paul A. Clemons, Alykhan F. Shamji, James E. Bradner, Michelle Palmer, Joshua A. Bittker, Vlado Dančík, Ted Liefeld, Benito Munoz, C. Suk-Yee Hon, Joanne D. Kotz, Nurdan Kuru, Mathias J. Wawer, Philip Montgomery, Ava Li, Benjamin Alexander, Joshua Gould, Christian K. Soule, Nicole E. Bodycombe, Victor Jones, Matthew E. Coletti, Edmund V. Price, Murat Cokol, Jaime H. Cheah, Matthew G. Rees, Brinton Seashore-Ludlow
Supplemental Table S1. Small-molecule Informer Set Description of the small-molecule informer set used in the sensitivity profiling experiment, including protein target or activity. Supplemental Table S2.Cancer cell-line panel Description of the canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330bf15e5f4c577c9f7b2b4ddfd54d5e
https://doi.org/10.1158/2159-8290.22530801
https://doi.org/10.1158/2159-8290.22530801
Autor:
Stuart L. Schreiber, Paul A. Clemons, Alykhan F. Shamji, James E. Bradner, Michelle Palmer, Joshua A. Bittker, Vlado Dančík, Ted Liefeld, Benito Munoz, C. Suk-Yee Hon, Joanne D. Kotz, Nurdan Kuru, Mathias J. Wawer, Philip Montgomery, Ava Li, Benjamin Alexander, Joshua Gould, Christian K. Soule, Nicole E. Bodycombe, Victor Jones, Matthew E. Coletti, Edmund V. Price, Murat Cokol, Jaime H. Cheah, Matthew G. Rees, Brinton Seashore-Ludlow
Supplemental Figure S1. Further characterization of the small-molecule Informer Set and comparisons between CTRP v1 and v2. Supplemental Figure S2. Cellular features of the CCL panel. Supplemental Figure S3. Details on ACME analysis described in this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad4befd455ce48a1c76862d653553c1
https://doi.org/10.1158/2159-8290.22530792.v1
https://doi.org/10.1158/2159-8290.22530792.v1
Autor:
Sourav Bandyopadhyay, Andrei Goga, Frank McCormick, Kevan M. Shokat, Nevan J. Krogan, Stuart L. Schreiber, Alykhan F. Shamji, Paul A. Clemons, Jaime Cheah, Antonio Sorrentino, Mike Shales, John Jascur, Jeff Johnson, Rebecca S. Levin, John D. Gordan, Taha Rakhshandehroo, Christina Yau, Dai Horiuchi, Alexandra Corella, Alicia Y. Zhou, Maria M. Martins
Supplementary Figure 1. Distribution of gene alterations in Breast TCGA and verification of expression of MCF10A cells. Supplementary Figure 2. Analysis of the MCF10A drug screen. Supplementary Figure 3. Significance of overlap between interactions f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02486064772f8aab6c1c615417b162ea
https://doi.org/10.1158/2159-8290.22529901
https://doi.org/10.1158/2159-8290.22529901
Autor:
Stuart L. Schreiber, Alykhan F. Shamji, Dineo Khabele, Jong W. Kim, Yun Min Chang, Stephanie Wang, Andrew J. Wilson, Pablo Tamayo, Michelle L. Stewart
A, quantification of western blot analysis for phosphorylation of MEK and ERK after treatment with decitabine for six days in a KRAS-mutant (MCAS) and KRAS-wild type (RMGI) ovarian cancer cell line as depicted in the main text. B, phosphorylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084ea2d12d5cae49d1b556a6ee92d0fe
https://doi.org/10.1158/0008-5472.22405875
https://doi.org/10.1158/0008-5472.22405875
Autor:
Stuart L. Schreiber, Alykhan F. Shamji, Dineo Khabele, Jong W. Kim, Yun Min Chang, Stephanie Wang, Andrew J. Wilson, Pablo Tamayo, Michelle L. Stewart
The differential mutual information score (Ic, methods) is used in this table to correlate pathways with activity of decitabine in solid tumor cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c843ae05b1cc812ad8218f387a7ed66c
https://doi.org/10.1158/0008-5472.22405866.v1
https://doi.org/10.1158/0008-5472.22405866.v1
Autor:
Stuart L. Schreiber, Alykhan F. Shamji, Dineo Khabele, Jong W. Kim, Yun Min Chang, Stephanie Wang, Andrew J. Wilson, Pablo Tamayo, Michelle L. Stewart
The differential mutual information score (Ic, methods) is used in this table to correlate gene mutations and copy number variations with activity of decitabine in solid tumor cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26908d97e948fe8fcad3f3a436442331
https://doi.org/10.1158/0008-5472.22405869
https://doi.org/10.1158/0008-5472.22405869