Zobrazeno 1 - 10 of 191 pro vyhledávání: '"F, Sempere"'
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Akademický článek
The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm generation, depressive-like behavior, and the reproductive axis in a sex-specific manner in mice
Autor: Brooke M. Van Loh, Alexandra M. Yaw, Joseph A. Breuer, Brooke Jackson, Duong Nguyen, Krystal Jang, Fabiola Ramos, Emily V. Ho, Laura J. Cui, Dominique L. M. Gillette, Lorenzo F. Sempere, Michael R. Gorman, Karen J. Tonsfeldt, Pamela L. Mellon, Hanne M. Hoffmann
Publikováno v: Frontiers in Endocrinology, Vol 14 (2023)
BackgroundThe suprachiasmatic nucleus (SCN) within the hypothalamus is a key brain structure required to relay light information to the body and synchronize cell and tissue level rhythms and hormone release. Specific subpopulations of SCN neurons, de
Externí odkaz: https://doaj.org/article/fe803c0e29b2466a93a3c13294295d69
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2
Akademický článek
Ductal tree ablation by local delivery of ethanol prevents tumor formation in an aggressive mouse model of breast cancer
Autor: Elizabeth Kenyon, Jennifer J. Westerhuis, Maximilian Volk, Jeremy Hix, Shatadru Chakravarty, Ethan Claucherty, Erin Zaluzec, Lisa Ramsey, Zach Madaj, Galen Hostetter, Bryn Eagleson, Erik Shapiro, Anna Moore, Lorenzo F. Sempere
Publikováno v: Breast Cancer Research, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Background Prophylactic mastectomy is the most effective intervention to prevent breast cancer. However, this major surgery has life-changing consequences at the physical, emotional, psychological, and social levels. Therefore, only high-ris
Externí odkaz: https://doaj.org/article/b1ea0341654f4fce87796e107f278d4b
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3
MicroRNA-210-3p Regulates Endometriotic Lesion Development by Targeting IGFBP3 in Baboons and Women with Endometriosis
Autor: Kentaro Kai, Niraj R. Joshi, Gregory W. Burns, Samantha M. Hrbek, Erin L. Vegter, Maria Ariadna Ochoa-Bernal, Yong Song, Genna E. Moldovan, Lorenzo F. Sempere, Eduardo H. Miyadahira, Paulo C. Serafini, Asgerally T. Fazleabas
Publikováno v: Reproductive Sciences.
MicroRNAs (miRs) play an important role in the pathophysiology of endometriosis; however, the role of miR-210 in endometriosis remains unclear. This study explores the role of miR-210 and its targets, IGFBP3 and COL8A1, in ectopic lesion growth and d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74cec57bc6a31717d9ca8daaa2a556c8
https://doi.org/10.1007/s43032-023-01253-5
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6
Data from UBE1L causes lung cancer growth suppression by targeting cyclin D1
Autor: Ethan Dmitrovsky, Konstantin Dragnev, Bret A. Hassel, Jesper B. Andersen, Vincent Memoli, Lorenzo F. Sempere, Sumit J. Shah, Fabrizio Galimberti, Candice C. Black, Xi Liu, Yongli Guo, David Sekula, Qing Feng
UBE1L is the E1-like ubiquitin-activating enzyme for the IFN-stimulated gene, 15-kDa protein (ISG15). The UBE1L-ISG15 pathway was proposed previously to target lung carcinogenesis by inhibiting cyclin D1 expression. This study extends prior work by r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff0821fa34065f58bb45b022ce78b4f
https://doi.org/10.1158/1535-7163.c.6531237
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7
Data from Fluorescence-Based Codetection with Protein Markers Reveals Distinct Cellular Compartments for Altered MicroRNA Expression in Solid Tumors
Autor: Murray Korc, Wendy Wells, Sakari Kauppinen, Jose R. Conejo-Garcia, Asli Silahtaroglu, Arief A. Suriawinata, Haoxu Ouyang, Todd Yezefski, Meir Preis, Lorenzo F. Sempere
Purpose: High-throughput profiling experiments have linked altered expression of microRNAs (miRNA) to different types of cancer. Tumor tissues are a heterogeneous mixture of not only cancer cells, but also supportive and reactive tumor microenvironme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1803cdaf2620ed06660b688b2e5d41
https://doi.org/10.1158/1078-0432.c.6519659.v1
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