Zobrazeno 1 - 10
of 403
pro vyhledávání: '"F, Sander"'
Autor:
Janni Nielsen, Johanne Lauritsen, Jannik N. Pedersen, Jan S. Nowak, Malthe K. Bendtsen, Giulia Kleijwegt, Kaija Lusser, Laia C. Pitarch, Julián V. Moreno, Matthias M. Schneider, Georg Krainer, Louise Goksøyr, Paul Khalifé, Sanne Simone Kaalund, Susana Aznar, Magnus Kjærgaard, Vita Sereikaité, Kristian Strømgaard, Tuomas P. J. Knowles, Morten Agertoug Nielsen, Adam F. Sander, Marina Romero-Ramos, Daniel E. Otzen
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-26 (2024)
Abstract α-Synuclein (α-syn) accumulates as insoluble amyloid but also forms soluble α-syn oligomers (αSOs), thought to be even more cytotoxic than fibrils. To detect and block the unwanted activities of these αSOs, we have raised 30 monoclonal
Externí odkaz:
https://doaj.org/article/e6e9d9eb66fb4db88fab4f91ceef8060
Autor:
Hyeog Kang, Mira Rakic Martinez, Kara-Lee Aves, Anna Kathrine Okholm, Hongquan Wan, Sylvie Chabot, Tahir Malik, Adam F. Sander, Robert Daniels
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110038- (2024)
Summary: Supplementing influenza vaccines with additional protective antigens such as neuraminidase (NA) is a promising strategy for increasing the breadth of the immune response. Here, we improved the immunogenicity and stability of secreted recombi
Externí odkaz:
https://doaj.org/article/13e7377e0416460cb9fb76152dcc60d3
Autor:
Kasper H. Björnsson, Maria R. Bassi, Anne S. Knudsen, Kara-Lee Aves, Èlia Morella Roig, Adam F. Sander, Lea Barfod
Publikováno v:
Vaccines, Vol 12, Iss 8, p 859 (2024)
A vaccine protecting against malaria caused by Plasmodium falciparum is urgently needed. The blood-stage invasion complex PCRCR consists of the five malarial proteins PfPTRAMP, PfCSS, PfRipr, PfCyRPA, and PfRH5. As each subcomponent represents an ess
Externí odkaz:
https://doaj.org/article/de514813e623405c8181553e600341c2
Autor:
Sebenzile K. Myeni, Anouk A. Leijs, Peter J. Bredenbeek, Shessy Torres Morales, Marissa E. Linger, Cyrielle Fougeroux, Sophie van Zanen-Gerhardt, Serge A. L. Zander, Adam F. Sander, Marjolein Kikkert
Publikováno v:
Vaccines, Vol 12, Iss 7, p 766 (2024)
The SARS-CoV-2 pandemic and the emergence of novel virus variants have had a dramatic impact on public health and the world economy, underscoring the need for detailed studies that explore the high efficacy of additional vaccines in animal models. In
Externí odkaz:
https://doaj.org/article/d28bc8a871ee4f499192070d34b38ba9
Autor:
Ilary Riedmiller, Cyrielle Fougeroux, Rasmus W Jensen, Ikhlaq H Kana, Adam F Sander, Thor G Theander, Thomas Lavstsen, Louise Turner
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0302243 (2024)
The sequestration of Plasmodium falciparum-infected erythrocytes to the host endothelium is central to the pathogenesis of malaria. The sequestration is mediated by the parasite´s diverse Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)
Externí odkaz:
https://doaj.org/article/9000c2c306034dd093a4dec13107e52d
Autor:
Jannick Prentoe, Christoph M. Janitzek, Rodrigo Velázquez-Moctezuma, Andreas Soerensen, Thomas Jørgensen, Stine Clemmensen, Vladislav Soroka, Susan Thrane, Thor Theander, Morten A. Nielsen, Ali Salanti, Jens Bukh, Adam F. Sander
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Development of B-cell-based hepatitis C virus (HCV) vaccines that induce broadly neutralizing antibodies (bNAbs) is hindered by extensive sequence diversity and low immunogenicity of envelope glycoprotein vaccine candidates, most notably sol
Externí odkaz:
https://doaj.org/article/17c5271bc53545d784e5135a4f4c87f6
Autor:
Jeong In Yang, Dagoberto Sepúlveda, Irina Vardia, Jakob Skov, Louise Goksøyr, Adam F. Sander, Niels Lorenzen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The Gram-negative bacterium A. salmonicida is the causal agent of furunculosis and used to be one of the most loss-causing bacterial infections in the salmonid aquaculture industry with a mortality rate of about 90% until the 1990s, when an inactivat
Externí odkaz:
https://doaj.org/article/df0ddfa7d8d2480c9523485b6cceb97f
Autor:
Kara-Lee Aves, Priscila R. Guerra, Ana H. Fresno, Mauro M. S. Saraiva, Eric Cox, Poul J. Bækbo, Morten A. Nielsen, Adam F. Sander, John E. Olsen
Publikováno v:
Pathogens, Vol 12, Iss 12, p 1388 (2023)
F4-positive enterotoxigenic Escherichia coli is associated with diarrhea and poor growth outcomes in neonatal and newly weaned piglets and is thus a major economic and welfare burden in the swine industry. Vaccination of sows with F4 fimbriae protect
Externí odkaz:
https://doaj.org/article/f415a7e958574ed0af94ad5f4c3cdf5c
Autor:
Cyrielle Fougeroux, Louise Goksøyr, Manja Idorn, Vladislav Soroka, Sebenzile K. Myeni, Robert Dagil, Christoph M. Janitzek, Max Søgaard, Kara-Lee Aves, Emma W. Horsted, Sayit Mahmut Erdoğan, Tobias Gustavsson, Jerzy Dorosz, Stine Clemmensen, Laurits Fredsgaard, Susan Thrane, Elena E. Vidal-Calvo, Paul Khalifé, Thomas M. Hulen, Swati Choudhary, Michael Theisen, Susheel K. Singh, Asier Garcia-Senosiain, Linda Van Oosten, Gorben Pijlman, Bettina Hierzberger, Tanja Domeyer, Blanka W. Nalewajek, Anette Strøbæk, Magdalena Skrzypczak, Laura F. Andersson, Søren Buus, Anette Stryhn Buus, Jan Pravsgaard Christensen, Tim J. Dalebout, Kasper Iversen, Lene H. Harritshøj, Benjamin Mordmüller, Henrik Ullum, Line S. Reinert, Willem Adriaan de Jongh, Marjolein Kikkert, Søren R. Paludan, Thor G. Theander, Morten A. Nielsen, Ali Salanti, Adam F. Sander
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Here the authors generate a capsid-like particle based vaccine candidate displaying the receptor-binding domain of the SARS-CoV-2 spike protein and show induction of neutralizing antibodies after intramuscular prime-boost immunization in mice.
Externí odkaz:
https://doaj.org/article/c047e4469bfc4df49317bf7ddb5a7a95
Autor:
Ariane Volkmann, Gerrit Koopman, Petra Mooij, Ernst J. Verschoor, Babs E. Verstrepen, Willy M. J. M. Bogers, Manja Idorn, Søren R. Paludan, Søren Vang, Morten A. Nielsen, Adam F. Sander, Carolin Schmittwolf, Hubertus Hochrein, Paul Chaplin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic. Here, we present non-human primate immunogenicity and protective efficacy data generated with the capsid virus-like particle (cVLP)-based vaccine ABNCoV2 th
Externí odkaz:
https://doaj.org/article/70276a3707f448aaac6b86a678a0b8dd