Zobrazeno 1 - 10
of 303
pro vyhledávání: '"F, Salamino"'
Publikováno v:
Journal of Biological Research, Vol 84, Iss 1 (2011)
To relate the alterations occurring in neurodegenerations with Ca2+ homeostasis dysregulation, we analyzed the functional properties of the Ca2+-dependent calpain/calpastatin system in neuronal cells of transgenic mice overexpressing human mutated -G
Externí odkaz:
https://doaj.org/article/570eceb16e1d44eda4f496e1d91a28cf
Publikováno v:
Journal of Biological Research, Vol 83, Iss 1 (2010)
Externí odkaz:
https://doaj.org/article/d3e6f0dfb7434c25b606042234a06673
Publikováno v:
Biochemical Journal. 325:721-726
The results presented provide more information on the sequential mechanism that promotes the Ca2+-induced activation of human erythrocyte μ-calpain under physiological conditions. The primary event in this process corresponds to the binding of Ca2+
Autor:
Ilaria Tedesco, Edon Melloni, Monica Averna, Mauro Michetti, F. Salamino, Sandro Pontremoli, Roberto Minafra
Publikováno v:
FEBS Letters. 392:11-15
The 80 kDa human erythrocyte calpain, when exposed to Ca2+, undergoes autoproteolysis that generates a 75 kDa species, with an increase in Ca2+ affinity. It is demonstrated here that this proteolytic modification proceeds through an initial step prod
Autor:
Edon Melloni, Noris Siliprandi, F. Salamino, Stefano Schiaffino, F. Di Lisa, Roberta Barbato, R. De Tullio, Sandro Pontremoli
Publikováno v:
Europe PubMed Central
The degradation of troponin (Tn) subunits by calpain was studied by incubating either isolated cardiac Tns or myocardial cryosections with two different calpain isoenzymes isolated from rat skeletal muscle. Western-blot analysis with monoclonal antib
Publikováno v:
Biochemical and Biophysical Research Communications. 202:1197-1203
Reversible interconversion between calpastatin I and calpastatin II, the phosphorylated form of the inhibitor, has been induced in rat heart perfused with the combination Ca2+/A23187 ionophore or with cAMP. In the presence of the ionophore and increa
Publikováno v:
Biochemical and Biophysical Research Communications. 199:1326-1332
Two calpastatins, with Mr 110 KD and named calpastatin I and II, have been isolated from rat heart and kidney and displayed distinct inhibitory efficiency with mu- and m-calpain, respectively, as those isolated from rat skeletal muscle. Whereas the l
Autor:
Monica Averna, Marco Pedrazzi, Edon Melloni, R. De Tullio, Sandro Pontremoli, F. Salamino, Roberto Stifanese
Publikováno v:
Journal of Biological Research, Vol 84, Iss 1 (2011)
To relate the alterations occurring in neurodegenerations with Ca2+ homeostasis dysregulation, we analyzed the functional properties of the Ca2+-dependent calpain/calpastatin system in neuronal cells of transgenic mice overexpressing human mutated -G
Publikováno v:
Journal of Molecular and Cellular Cardiology.
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 144