Zobrazeno 1 - 10
of 589
pro vyhledávání: '"F, Pera"'
Autor:
Timothy D. Arthur, Jennifer P. Nguyen, Agnieszka D’Antonio-Chronowska, Hiroko Matsui, Nayara S. Silva, Isaac N. Joshua, iPSCORE Consortium, André D. Luchessi, William W. Young Greenwald, Matteo D’Antonio, Martin F. Pera, Kelly A. Frazer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Stem cells exist in vitro in a spectrum of interconvertible pluripotent states. Analyzing hundreds of hiPSCs derived from different individuals, we show the proportions of these pluripotent states vary considerably across lines. We discover
Externí odkaz:
https://doaj.org/article/16ce60b0912a42e6aef00bc8707fda12
Autor:
Benjamin Rader, Christina M. Astley, Kara Sewalk, Paul L. Delamater, Kathryn Cordiano, Laura Wronski, Jessica Malaty Rivera, Kai Hallberg, Megan F. Pera, Jonathan Cantor, Christopher M. Whaley, Dena M. Bravata, Leslie Lee, Anita Patel, John S. Brownstein
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-11 (2022)
Rader et al. model spatial accessibility to COVID-19 vaccines in the US, identifying vaccine deserts where access was insufficient during the first phase of the rollout. Rural areas and medically vulnerable populations are found to have poorer access
Externí odkaz:
https://doaj.org/article/25e953cfe3c74277b565e29b3f07e37f
Autor:
Daniel Cortes, Martin F. Pera
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-9 (2021)
Abstract Traumatic brain injury (TBI) is one of the leading causes of death among young people, and is increasingly prevalent in the aging population. Survivors of TBI face a spectrum of outcomes from short-term non-incapacitating injuries to long-la
Externí odkaz:
https://doaj.org/article/01427823e6a84131ae450ddc7b8aff36
Autor:
Kevin X. Lau, Elizabeth A. Mason, Joshua Kie, David P. De Souza, Joachim Kloehn, Dedreia Tull, Malcolm J. McConville, Andrew Keniry, Tamara Beck, Marnie E. Blewitt, Matthew E. Ritchie, Shalin H. Naik, Daniela Zalcenstein, Othmar Korn, Shian Su, Irene Gallego Romero, Catrina Spruce, Christopher L. Baker, Tracy C. McGarr, Christine A. Wells, Martin F. Pera
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Human pluripotent cells (hPSCs) in standard culture are similar to mouse epiblast cells, but heterogeneity within hPSC cultures complicates comparisons. Here the authors show that a subpopulation of hPSCs enriched for self-renewal capacity have disti
Externí odkaz:
https://doaj.org/article/1f87c566710a45a38bb6a81fc0b27bcc
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 169-174 (2020)
Over the past few years, a number of research groups have reported striking progress on the generation of in vitro models from mouse and human stem cells that replicate aspects of early embryonic development. Not only do these models reproduce some k
Externí odkaz:
https://doaj.org/article/5e818a672a7742d88aea97c8edf3740a
Autor:
Megan F. Pera, Mary M. Cain, Ashleigh Emerick, Stephanie Katz, Nicole A. Hirsch, Bruce W. Sherman, Dena M. Bravata
Publikováno v:
Journal of Primary Care & Community Health, Vol 12 (2021)
Objectives: To evaluate the prevalence of social determinants of health (SDoH) factors in a large commercially-insured population and to characterize the prevalence of common conditions (eg, diabetes, behavioral health issues) and addressable health
Externí odkaz:
https://doaj.org/article/57d98cc675954981bb1c6980e3c4793d
Autor:
Peter W. Andrews, Ivana Barbaric, Nissim Benvenisty, Jonathan S. Draper, Tenneille Ludwig, Florian T. Merkle, Yoji Sato, Claudia Spits, Glyn N. Stacey, Haoyi Wang, Martin F. Pera
Publikováno v:
Cell Stem Cell. 29:1624-1636
It is well established that human pluripotent stem cells (hPSCs) can acquire genetic and epigenetic changes during culture in vitro. Given the increasing use of hPSCs in research and therapy and the vast expansion in the number of hPSC lines availabl
Autor:
Connie J. Eaves, Martin F. Pera
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 167-168 (2020)
Stem Cell Reports frequently receives manuscripts dealing with the topic of cancer stem cells. Many of the submissions on this topic have major shortcomings in their content or limits to the conclusions that can be drawn from the results presented. T
Externí odkaz:
https://doaj.org/article/0b4d4bc4f39b47cba526dae4f34c5bb5
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