Zobrazeno 1 - 10
of 116
pro vyhledávání: '"F, Natt"'
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:991-994
Chimeric oligodeoxyribonucleotides where the phosphodiester linkage -C3'-O-PO2--O-CH2-C4'- of DNA is substituted by the amide linkage -C3'-CH2-CH*(CH3)-CO-NH-CH2-C4' (*either R or S stereochemistry) have been prepared and their binding to RNA targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3bff42d0852c5be809ef07cdbcf69a8
https://doi.org/10.1081/ncn-100002475
https://doi.org/10.1081/ncn-100002475
Publikováno v:
Inflammation Research. 49:692-699
Objective and Design: This study was designed to establish whether phosphorothioate (PS) antisense oligonucleotides (AS-ODN) targeted to Stat6 were active in vivo in a mouse model of active sensitisation.¶Materials: Female Balb/c mice (6-8) per grou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14bd59192e92f7472e0fc9061de6c485
https://doi.org/10.1007/s000110050648
https://doi.org/10.1007/s000110050648
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 120:754-757
Paclitaxel represents a novel antitumour agent with demonstrated activity in cisplatin-sensitive tumours, particularly ovarian cancer. In addition, responses to paclitaxel have been observed in patients with cisplatin-refractory ovarian cancer. The r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c033f79b4a975f499ed1a4b4aae7137
https://doi.org/10.1007/bf01194278
https://doi.org/10.1007/bf01194278
Autor:
W. Sondern, H.E. Wander, W.D. Hirschmann, T. Wagner, K.H. Koniczeck, E. Günther, W. Roth, H.F. Hinrichs, B. Steinke, F. Natt
Publikováno v:
Oncology Research and Treatment. 16:252-259
Background: In most studies comparing 5-fluorouracil (5-FU) monotherapy versus the combination of folinic acid and 5-FU in the treatment of advanced colorectal cancer, a low dose of 5-FU was given in monotherapy, possibly leading to impaired results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6bb60818375092d9f499753c6fa51e
https://doi.org/10.1159/000218270
https://doi.org/10.1159/000218270
Publikováno v:
Anti-cancer drug design. 15(6)
The present study was performed to identify a potent and sequence-specific antisense oligonucleotide (ASO), to inhibit Hdm2 expression in human cancer cell lines and to study the downstream consequences. Ten chimeric 2'-O-methoxyethyl (MoE)-modified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a50ce9a172b9990cc3a6e0a90dd286b2
https://pubmed.ncbi.nlm.nih.gov/11716435
https://pubmed.ncbi.nlm.nih.gov/11716435
Autor:
U, Zangemeister-Wittke, S H, Leech, R A, Olie, A P, Simões-Wüst, O, Gautschi, G H, Luedke, F, Natt, R, Häner, P, Martin, J, Hall, C M, Nalin, R A, Stahel
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)
Bcl-2 and Bcl-xL are inhibitors of apoptosis frequently overexpressed in solid tumors. The bcl-2 and bcl-xL mRNAs share a region of homology comprising nucleotides 605-624 and 687-706, respectively, which differs by only three nucleotides. This seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ade2cf6dd501508a5178e492c98749c
https://pubmed.ncbi.nlm.nih.gov/10873111
https://pubmed.ncbi.nlm.nih.gov/10873111
Autor:
B, Steinke, E, Günther, W D, Hirschmann, W, Sondern, K H, Koniczek, H E, Wander, F, Natt, T, Wagner, H F, Hinrichs, D, Werdier
Publikováno v:
Seminars in oncology. 19(2 Suppl 3)
Patients with advanced colorectal cancer were randomized to receive either fluorouracil (5-FU) 370 mg/m2 IV days 1 to 5 followed by weekly applications of 5-FU 600 mg/m2 or the same doses of 5-FU preceded by folinic acid 200 mg/m2. Because of toxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fba15c1cbcfbc781b502080189a74ab2
https://pubmed.ncbi.nlm.nih.gov/1557640
https://pubmed.ncbi.nlm.nih.gov/1557640
Autor:
H. Poliwoda, U. Lammers, U. Räth, C.-H. Köhne-Wömpner, F. Natt, Andreas Harstrick, P. Reichhardt, Hansjochen Wilke, Wolfgang Siegert, Lothar Bergmann, H.-J. Schmoll, G. Dölken, J. Hohnloser
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 2(3)
Forty-eight patients with advanced testicular cancer, defined as abdominal mass greater than 10 cm, mediastinal mass greater than 5 cm, more than 20 lung metastases, or visceral organ involvement were treated with an intensive, alternating five-drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d481fb0f92651151c246376290435d
https://pubmed.ncbi.nlm.nih.gov/1645987
https://pubmed.ncbi.nlm.nih.gov/1645987
Publikováno v:
European Journal of Cancer Supplements. 4:181
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d14a1fb8801d04201e180b4ac23386b4
https://doi.org/10.1016/s1359-6349(06)70603-6
https://doi.org/10.1016/s1359-6349(06)70603-6
Publikováno v:
Molecular Psychiatry. 10:714-714
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce3d968ba295fc3b05c8ca119c2db9c9
https://doi.org/10.1038/sj.mp.4001715
https://doi.org/10.1038/sj.mp.4001715