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Akademický článek

In situ conservation of wild potato germplasm in Argentina: Example and possibilities

Autor: Carlos F. Marfil, Verónica Hidalgo, Ricardo W. Masuelli

Publikováno v: Global Ecology and Conservation, Vol 3, Iss C, Pp 461-476 (2015)

The potato is the third most important food crop worldwide and in situ conservation of its wild relatives is considered an urgent priority. Although regions of the Americas with high wild potato species richness have been identified, the need to iden

Externí odkaz: https://doaj.org/article/3bd8e75ea9704acc8afea885d641f492

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Akademický článek

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Akademický článek

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Akademický článek

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Genomic instability in Solanum tuberosum × Solanum kurtzianum interspecific hybrids

Autor: L Comai, Ricardo Williams Masuelli, J Davison, C F Marfil

Publikováno v: Genome. 49:104-113

The use of interspecific crosses in breeding is an important strategy in improving the genetic base of the modern cultivated potato, Solanum tuberosum L. Until now, it has normally been interspecific Solanum hybrids that have been morphologically and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde309cbd6d49352ad6269a92250690d
https://doi.org/10.1139/g05-088

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Determination of a new oral iron chelator, ICL670, and its iron complex in plasma by high-performance liquid chromatography and ultraviolet detection

Autor: Patrick Mangoni, F. Marfil, R Séchaud, H Humbert, M.C. Rouan, G Maurer

Publikováno v: Journal of Chromatography B: Biomedical Sciences and Applications. 755:203-213

ICL670 is a representative of a new class of orally active tridentate selective iron chelators. Two molecules of ICL670 are required to form a complete hexacoordinate chelate Fe-[ICL670]2 with one ferric iron. A simple and rapid HPLC-UV method for th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af0f9806a8c62e8a9bcf3d4acaf17bc4
https://doi.org/10.1016/s0378-4347(01)00079-2

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Practice of solid-phase extraction and protein precipitation in the 96-well format combined with high-performance liquid chromatography–ultraviolet detection for the analysis of drugs in plasma and brain

Autor: M.C. Rouan, C Buffet, G Maurer, H Humbert, F. Marfil, L Masson

Publikováno v: Journal of Chromatography B: Biomedical Sciences and Applications. 754:45-55

C18 Empore 96-well extraction disc plates have been employed for the analysis of three drugs with different polarities in plasma in conjunction with HPLC-UV, rufinamide, ICL670 and an anticonvulsant agent (AA1) in an early stage of development. With

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e50f13c379b344823f81981ecfdcb88
https://doi.org/10.1016/s0378-4347(00)00576-4

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Randomized comparative trial of triflusal and aspirin following acute myocardial infarction

Autor: E Navarro, Alfonso Castro-Beiras, D. Garcia-Dorado, A. Cabadés, José María Cruz-Fernández, L Martín-Jadraque, V López García-Aranda, Ferran Torres, Lorenzo López-Bescós, J. Velasco, F Marfil

Publikováno v: European Heart Journal. 21:457-465

Aims To compare the efficacy and tolerability of the antiplatelet agent triflusal with aspirin in the prevention of cardiovascular events following acute myocardial infarction. Methods and results In this double-blind, multicentre, sequential design

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176364533455a09c35e57bc9d79bbca2
https://doi.org/10.1053/euhj.1999.1874

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The effect of age on the pharmacokinetics of valsartan

Autor: J. M. Cardot, A. Jaouen, F. Ezzet, P. Lloyd, Antoine Sioufi, F. Marfil, J. Godbillon

Publikováno v: Biopharmaceutics & Drug Disposition. 19:237-244

Twelve young (mean age 23 years, range 18–28) and 12 elderly (mean age 76 years, range 65–89) volunteers were given a single oral dose of 80 mg valsartan after an overnight fast. Each group consisted of six male and six female subjects. Mean syst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f3bc94531b79926aa9fdba9294ceb26e
https://doi.org/10.1002/(sici)1099-081x(199805)19:4<237::aid-bdd100>3.0.co

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Absolute bioavailability of letrozole in healthy postmenopausal women

Autor: H. Howald, F. Marfil, J. M. Cardot, Antoine Sioufi, N. Gauducheau, F. Vreeland, V. Pineau, J. Godbillon, C. Czendlik, Ch. Pfister, A. Jaouen

Publikováno v: Biopharmaceutics & Drug Disposition. 18:779-789

Letrozole is a new non-steroidal inhibitor of the aromatase enzyme system. It is currently under development for the treatment of postmenopausal women with advanced breast cancer. Absolute bioavailability of letrozole when given orally as one 2.5 mg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6afe1b37ed233501529ab3a39555cab
https://doi.org/10.1002/(sici)1099-081x(199712)18:9<779::aid-bdd64>3.0.co

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