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of 50
pro vyhledávání: '"F, Loncarevic"'
Autor:
Julia Diegmann, Kerstin Junker, Ivan F. Loncarevic, Susanne Michel, Bettina Schimmel, Ferdinand von Eagelinq
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 11, Pp 933-938 (2006)
Tumors can escape immune recognition and destruction through the induction of apoptosis in lymphocytes. Although renal cell carcinoma (RCC) is able to prevent immune recognition, only a few genes (such as FasL) that are relevant for RCC immune escape
Externí odkaz:
https://doaj.org/article/956ce9a19e9d4a8fad3c3679c6be45a2
Publikováno v:
Pediatric Blood & Cancer. 51:356-362
Background Adrenocortical tumours (ACT) in children are rare and, if malignant, often associated with poor prognosis. Relevant cytogenetic factors for prognosis are hardly available. Procedures We analysed 14 adrenocortical cancers (ACC) of children
Autor:
Ivan F. Loncarevic, Ferdinand von Eagelinq, Bettina Schimmel, Kerstin Junker, Julia Diegmann, Susanne Michel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 11, Pp 933-938 (2006)
Tumors can escape immune recognition and destruction through the induction of apoptosis in lymphocytes. Although renal cell carcinoma (RCC) is able to prevent immune recognition, only a few genes (such as FasL) that are relevant for RCC immune escape
Autor:
Ivan F. Loncarevic, Frank-D. Böhmer, Sebastian Scholl, K. Höffken, Joachim H. Clement, R. Müller
Publikováno v:
Leukemia Research. 30:633-642
Among activating Flt3 mutations that have been shown in 25–30% of acute myeloid leukaemia (AML) Flt3-internal tandem duplication (ITD) mutations are predominant. We investigated the influence of all- trans -retinoic acid (ATRA) and granulocyte colo
Autor:
Sebastian Scholl, Claudia Krause, Ivan F. Loncarevic, K. Höffken, Christa Kunert, Joachim H. Clement
Publikováno v:
Leukemia Research. 29:849-853
We present our first experiences with determination of minimal residual disease (MRD) based on patient specific Flt3-ITD (internal tandem duplication) mutations. We analysed MRD status of 11 AML patients in a retrospective investigation and its poten
Autor:
Claudia Krause, Ivan F. Loncarevic, Rouven Müller, Sebastian Scholl, Herbert G. Sayer, Klaus Höffken, Ulrich Wedding, Joachim H. Clement, Christa Kunert
Publikováno v:
Journal of Laboratory and Clinical Medicine. 145:295-304
Among activating class III receptor tyrosine kinase (Flt3) mutations, internal tandem duplications of Flt3 (Flt3-ITD) are detected in about 25% of patients with acute myeloid leukemia (AML). In contrast, mutations within the tyrosine kinase domain of
Autor:
Ivan F. Loncarevic, Monika Ziegler, Jennifer Römer, Heike Starke, Thomas Liehr, Wolfgang Fiedler, Anita Heller, Uwe Claussen, Joachim H. Clement, Cordula Bleck
Publikováno v:
Genes, Chromosomes and Cancer. 34:193-200
The objective of this study was to characterize the ABL1-BCR fusion gene in 76 BCR-ABL1-positive chronic myeloid leukemia (CML) patients regarding expression as well as genomic status, to assess the frequency of ABL1-BCR gene deletion in these patien
Autor:
Ivan F. Loncarevic, Johannes Lemke, Gabriele Senger, Bernd Zabel, Ilse Chudoba, Catherine Henry, Markus Stumm, Uwe Claussen
Publikováno v:
Human Genetics. 108:478-483
Characterisation of chromosome rearrangements using conventional banding techniques often fails to determine the localisation of breakpoints precisely. In order to improve the definition of chromosomal breakpoints, the high-resolution multicolour ban
Autor:
Uwe Claussen, Heike Starke, Iwona Wlodarska, Ivan F. Loncarevic, Angela Nietzel, Thomas Liehr, Mariano Rocchi, Anita Heller, Volkmar Beensen, Wolfgang Fiedler
Publikováno v:
Human Genetics. 108:199-204
Centromere-specific multi-color FISH (cenM-FISH) is a new multicolor FISH technique that allows the simultaneous characterization of all human centromeres by using labeled centromeric satellite DNA as probes. This approach allows the rapid identifica
Autor:
Stig Bojesen, Dirk Scharr, Uta Fuchs, Rainer M. Bohle, Petra Korth, Arndt Borkhardt, Traudl Henn, Oskar A. Haas, Susanne Viehmann, Jochen Harbott, Reinald Repp, Ulrich Jaeger, Dominique Bartelheimer, Fritz Lampert, Ivan F. Loncarevic
Publikováno v:
Proceedings of the National Academy of Sciences. 97:9168-9173
We have isolated the human GRAF gene (for GTPase regulator associated with the focal adhesion kinase pp125 FAK ). This gene was fused with MLL in a unique t(5;11)(q31;q23) that occurred in an infant with juvenile myelomonocytic leukemia. GRAF encodes