Zobrazeno 1 - 10
of 129
pro vyhledávání: '"F, Lepault"'
Publikováno v:
The Journal of Immunology. 152:5969-5978
The nonobese diabetic mouse is a relevant model for insulin-dependent diabetes mellitus which results from the destruction of pancreatic beta cells by mononuclear cells infiltrating the islets of Langerhans. Other organs such as salivary glands displ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4260761ba1ae77a6520125ab00bfae65
https://doi.org/10.4049/jimmunol.152.12.5969
https://doi.org/10.4049/jimmunol.152.12.5969
Publikováno v:
Diabetes. 42:1823-1828
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc1d67bf3149c6f110385723f53ea49f
https://doi.org/10.2337/diabetes.42.12.1823
https://doi.org/10.2337/diabetes.42.12.1823
Publikováno v:
The International Journal of Cell Cloning. 10:173-181
Expression of diabetes susceptibility genes at the hemopoietic stem cell level is sufficient for the development of the disease in nonobese diabetic (NOD) mice. This work investigated whether the defects that reside within the stem cells have consequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64209d9be8cddc2c19be3d82362cae2a
https://doi.org/10.1002/stem.5530100308
https://doi.org/10.1002/stem.5530100308
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(5)
Pathogenic autoreactive T lymphocytes are mediators of spontaneous insulin-dependent diabetes in nonobese diabetic (NOD) mice. This is demonstrated by their capacity to transfer diabetes into syngeneic immunoincompetent recipients. In addition, espec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bab2a91738e877d47ec2a8b2fef8efb2
https://pubmed.ncbi.nlm.nih.gov/9725264
https://pubmed.ncbi.nlm.nih.gov/9725264
Autor:
F, Lepault, M C, Gagnerault
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 78(5)
We have previously shown that in the nonobese diabetic (NOD) mouse, an experimental model for autoimmune insulin-dependent diabetes, spleen diabetogenic T cells are contained within the T-cell subpopulation that express no or low levels of L-selectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55455321cff7d7ab17b3a528fb7bd09c
https://pubmed.ncbi.nlm.nih.gov/9605180
https://pubmed.ncbi.nlm.nih.gov/9605180
Autor:
F. Lepault, Maria Leite-de-Moraes, Anne Arnould, Lucienne Chatenoud, Elke Schneider, Michel Dy, François Machavoine, A. Ben-Amor
Publikováno v:
Clinical and experimental immunology. 103(3)
SUMMARY Anti-CD3 MoAb treatment is widely used as an immunosuppressive therapy. In the present study we examined the in vitro T cell response in mice having received 24 h before a single i.v. injection of 10 μg of anti-CD3 MoAb. We found that spleno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02685c9e9f1352269153680f398901f2
https://pubmed.ncbi.nlm.nih.gov/8608651
https://pubmed.ncbi.nlm.nih.gov/8608651
Role of interleukin-2 receptors in the suppressive effect of spleen cells from anti-CD3-treated mice
Autor:
A, Ben-Amor, Leite-De-Moraes MdC, F, Lepault, E, Schneider, F, Machavoine, A, Arnould, L, Chatenoud, M, Dy
Publikováno v:
European cytokine network. 6(4)
In the present study, we demonstrate that unresponsive spleen T cells from mice injected with a low dose of anti-CD3 mAb (single 10 micrograms i.v. injection) significantly inhibit Con A-induced proliferation of normal spleen cells. The induction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64a5e156d76b4900e2415541a759dec8
https://pubmed.ncbi.nlm.nih.gov/8789286
https://pubmed.ncbi.nlm.nih.gov/8789286
Publikováno v:
Advances in experimental medicine and biology. 355
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c13eb7d06c7a0a0913da37f5865f27e
https://pubmed.ncbi.nlm.nih.gov/7709812
https://pubmed.ncbi.nlm.nih.gov/7709812
Publikováno v:
The Journal of Immunology. 140:1431-1434
Bone marrow-derived precursors colonize the thymus, where they constitute the minor L3T4-Lyt2- subset which can give rise to all thymocyte subpopulations. We show in the present paper that L3T4-Lyt2- population depleted of Ia+, Mac-1+ cells contain p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73ad22a74000623e5f1b411a44c8ae0a
https://doi.org/10.4049/jimmunol.140.5.1431
https://doi.org/10.4049/jimmunol.140.5.1431
Publikováno v:
The Journal of Immunology. 131:64-69
Using a short-term in vivo assay, we studied bone marrow cells capable of homing to the thymus of lethally irradiated recipients. In the bone marrow, these cells lack the T cell markers Thy-1 and Lyt. Soon after their homing into the thymus, however,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19fa3c233f23ebff26a3afe8ba1adf88
https://doi.org/10.4049/jimmunol.131.1.64
https://doi.org/10.4049/jimmunol.131.1.64