Zobrazeno 1 - 10
of 175
pro vyhledávání: '"F, Lebeau"'
Publikováno v:
Smart Agricultural Technology, Vol 8, Iss , Pp 100522- (2024)
Grasslands represent a key element of agroecosystems for sustainable food systems. A better understanding of the grazing behaviour of domestic herbivores is essential to support innovations for grassland management and define grazing practices that s
Externí odkaz:
https://doaj.org/article/38c9dabc7aa54f02b28f3e26b30d3c14
Publikováno v:
African and Mediterranean Agricultural Journal - Al Awamia, Vol 0, Iss 133, Pp 139-169 (2022)
Un système de pulvérisation par injection directe (DIS) consiste à injecter en ligne un produit chimique liquide dans de l’eau jouant le rôle d’un liquide porteur. Cette technologie est techniquement appréciée comme méthode propre pour ré
Externí odkaz:
https://doaj.org/article/cbc34a98443a400085dfa5fc6f50c55b
Autor:
Paul F. Lebeau, Jae Hyun Byun, Khrystyna Platko, Paul Saliba, Matthew Sguazzin, Melissa E. MacDonald, Guillaume Paré, Gregory R. Steinberg, Luke J. Janssen, Suleiman A. Igdoura, Mark A. Tarnopolsky, S. R. Wayne Chen, Nabil G. Seidah, Jakob Magolan, Richard C. Austin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Caffeine may reduce cardiovascular disease risk, but the underlying mechanisms for these effects are incompletely understood. Here the authors report that caffeine inhibits the activation of the transcription factor SREBP2 to promote LDLc clearance t
Externí odkaz:
https://doaj.org/article/6733f73670aa4d5a807867eed2c293ea
Autor:
Paul F. Lebeau, Jae Hyun Byun, Khrystyna Platko, Ali A. Al-Hashimi, Šárka Lhoták, Melissa E. MacDonald, Aurora Mejia-Benitez, Annik Prat, Suleiman A. Igdoura, Bernardo Trigatti, Kenneth N. Maclean, Nabil G. Seidah, Richard C. Austin
Publikováno v:
JHEP Reports, Vol 1, Iss 6, Pp 418-429 (2019)
Background & Aims: The fatty acid translocase, also known as CD36, is a well-established scavenger receptor for fatty acid (FA) uptake and is abundantly expressed in many metabolically active tissues. In the liver, CD36 is known to contribute to the
Externí odkaz:
https://doaj.org/article/bc29e44a6d4f455ca1909cd11dae2193
Autor:
Khrystyna Platko, Paul F. Lebeau, Jae Hyun Byun, Samantha V. Poon, Emily A. Day, Melissa E. MacDonald, Nicholas Holzapfel, Aurora Mejia-Benitez, Kenneth N. Maclean, Joan C. Krepinsky, Richard C. Austin
Publikováno v:
Molecular Metabolism, Vol 27, Iss , Pp 62-74 (2019)
Objective: Growth differentiation factors (GDFs) and bone-morphogenic proteins (BMPs) are members of the transforming growth factor β (TGFβ) superfamily and are known to play a central role in the growth and differentiation of developing tissues. A
Externí odkaz:
https://doaj.org/article/9a0aa889f2324bde96265d42a39b9a03
Publikováno v:
MethodsX, Vol 6, Iss , Pp 1174-1180 (2019)
Cell death is a common driver of human disease and is frequently studied in a variety of in vitro settings. There currently exists a range of commercially available assays to examine cell death, however, most are costly and require assay-specific exp
Externí odkaz:
https://doaj.org/article/57a5cdfdbd704263a585bc51d5f6281d
Publikováno v:
Metabolites, Vol 12, Iss 3, p 215 (2022)
The importance of the proprotein convertase subtilisin/kexin type-9 (PCSK9) gene was quickly recognized by the scientific community as the third locus for familial hypercholesterolemia. By promoting the degradation of the low-density lipoprotein rece
Externí odkaz:
https://doaj.org/article/cf11d916a02a453886c0574170f7bfd4
Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity
Autor:
Jae Hyun Byun, Paul F. Lebeau, Khrystyna Platko, Rachel E. Carlisle, Mahi Faiyaz, Jack Chen, Melissa E. MacDonald, Yumna Makda, Tamana Yousof, Edward G. Lynn, Jeffrey G. Dickhout, Joan C. Krepinsky, Fiona Weaver, Suleiman A. Igdoura, Nabil G. Seidah, Richard C. Austin
Publikováno v:
Kidney360. 3:1394-1410
Autor:
Khrystyna Platko, Paul F. Lebeau, Joshua P. Nederveen, Jae Hyun Byun, Melissa E. MacDonald, Jacqueline M. Bourgeois, Mark A. Tarnopolsky, Richard C. Austin
Publikováno v:
Nutrients; Volume 15; Issue 10; Pages: 2410
Objective: Metabolic Syndrome (MetS) affects hundreds of millions of individuals and constitutes a major cause of morbidity and mortality worldwide. Obesity is believed to be at the core of metabolic abnormalities associated with MetS, including dysl
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