Zobrazeno 1 - 10
of 491
pro vyhledávání: '"F, Kierszenbaum"'
Autor:
S Majumder, F Kierszenbaum
Publikováno v:
The Journal of Immunology. 156:3866-3874
Acute infection with Trypanosoma cruzi, the agent of Chagas' disease, is accompanied by multiple manifestations of immunosuppression, and this parasite has been shown to inhibit T and B lymphocyte functions in vitro through a mechanism involving impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74f70a6ca299c1db9079f86abce27855
https://doi.org/10.4049/jimmunol.156.10.3866
https://doi.org/10.4049/jimmunol.156.10.3866
Autor:
F. Kierszenbaum, M.B. Sztein
Publikováno v:
Parasitology Today. 9:424-428
Acute infection with Trypanosoma cruzi or its African relatives, including T. brucei rhodesiense, T. b. gambiense, T. b. brucei and T. congolense, is frequently accompanied by manifestations of immunological dysfunction. Initially investigators catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def5d74f30ea3ec594084b300c933623
https://doi.org/10.1016/0169-4758(93)90053-i
https://doi.org/10.1016/0169-4758(93)90053-i
Autor:
S Majumder, F Kierszenbaum
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:2235-2238
We studied the effects of two N,N'-bis(benzyl)-substituted polyamine analogs on the capacities of Trypanosoma cruzi to invade and multiply within a mammalian host cell. At concentrations as low as 1 microM, these compounds reduced significantly the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a97f79826795e91f059f150b92d76d
https://doi.org/10.1128/aac.37.10.2235
https://doi.org/10.1128/aac.37.10.2235
Publikováno v:
The Journal of Immunology. 144:3558-3562
We studied the effects of Trypanosoma cruzi secretion products on the capacity of helper (Th) and cytotoxic (Tc) cells to express IL-2R, CD3, CD4, and CD8 in response to PHA or anti-CD3 stimulation. To this end, we used a culture system in which bloo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4312ab6935ae42d48115e0cd00c4974a
https://doi.org/10.4049/jimmunol.144.9.3558
https://doi.org/10.4049/jimmunol.144.9.3558
Publikováno v:
European journal of immunology. 29(5)
The Trypanosoma cruzi membrane glycoprotein AGC10 has been shown to alter some human macrophage functions (De Diego, J. L. et al., J. Immunol. 1997. 159: 4983-4989). We show here that, in the presence of AGC10, [3H]thymidine incorporation by normal h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e39317a56b22356d50097cef80af0df
https://pubmed.ncbi.nlm.nih.gov/10359123
https://pubmed.ncbi.nlm.nih.gov/10359123
Publikováno v:
The Journal of parasitology. 82(4)
The intracellular levels of interleukin (IL)-2, IL-4, IL-5 and interferon-gamma (IFN-gamma) produced by mitogen-stimulated normal human blood lymphocytes were found to be markedly reduced in cultures containing purified Trypanosoma cruzi trypomastigo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::517411e12639ab03fc2376e2115da97c
https://pubmed.ncbi.nlm.nih.gov/8691380
https://pubmed.ncbi.nlm.nih.gov/8691380
Publikováno v:
Parasite immunology. 17(4)
A substantial proportion of human peripheral blood mononuclear cells (PBMC) manifested a decreased capacity to express membrane interferon-gamma receptors (IFN-gamma R) when co-cultured with Trypanosoma cruzi. Among the lymphocytes, B cells accounted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00a362b687c11eddb01cf59af092856b
https://pubmed.ncbi.nlm.nih.gov/7624161
https://pubmed.ncbi.nlm.nih.gov/7624161
Publikováno v:
Immunology. 80(3)
There has been disagreement about the ability of exogenous interleukin-2 (IL-2) to restore responsiveness to lymphocytes from either Trypanosoma cruzi-infected animals or normal individuals co-cultured with this parasite. The discrepancy has been att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe7540178ecbe98c98a48127149431d2
https://pubmed.ncbi.nlm.nih.gov/8288318
https://pubmed.ncbi.nlm.nih.gov/8288318
Publikováno v:
Biological research. 26(1-2)
The mechanisms by which Trypanosoma cruzi causes dysfunction in normal human lymphocytes was studied by using an in vitro system in which purified parasites and normal peripheral blood mononuclear cells are co-cultured in the presence or absence of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::647254f466c87794c7c592eea9dad1b4
https://pubmed.ncbi.nlm.nih.gov/7670532
https://pubmed.ncbi.nlm.nih.gov/7670532
Publikováno v:
The Journal of parasitology. 78(3)
DL-alpha-difluoromethylarginine (DFMA), a specific, irreversible inhibitor of arginine decarboxylase (ADC), decreases the capacity of Trypanosoma cruzi to invade and multiply within different types of mammalian host cells in vitro. In this work we fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71bbc1c939e0f6ff9d129273677e937f
https://pubmed.ncbi.nlm.nih.gov/1597782
https://pubmed.ncbi.nlm.nih.gov/1597782