Zobrazeno 1 - 10
of 847
pro vyhledávání: '"F, Irvine"'
Publikováno v:
Cancer Medicine, Vol 11, Iss 3, Pp 571-591 (2022)
Abstract Cases of hepatocellular carcinoma (HCC) are rapidly rising. This is particularly the case in the Western world, as a result of increasing rates of chronic liver disease, secondary to lifestyle‐associated risk factors and the lack of an est
Externí odkaz:
https://doaj.org/article/9029b0ae00e0465984101e23a1c884db
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Cancer-associated fibroblasts (CAFs) are a key component of the tumour microenvironment with evidence suggesting they represent a heterogeneous population. This study summarises the prognostic role of all proteins characterised in CAFs with
Externí odkaz:
https://doaj.org/article/e5c522e948c04a42ab5034d979c930e4
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background Meta-analyses of studies evaluating survival (time-to-event) outcomes are a powerful technique to assess the strength of evidence for a given disease or treatment. However, these studies rely on the adequate reporting of summary s
Externí odkaz:
https://doaj.org/article/74a0072899af41c7bc136736c96f46fd
Autor:
Drolaiz H. W. Liu, Young-Woo Kim, Nina Sefcovicova, Jon P. Laye, Lindsay C. Hewitt, Andrew F. Irvine, Vincent Vromen, Yannick Janssen, Naser Davarzani, Gregorio E. Fazzi, Shahab Jolani, Veerle Melotte, Derek R. Magee, Myeong-Cherl Kook, Hyunki Kim, Rupert Langer, Jae-Ho Cheong, Heike I. Grabsch
Publikováno v:
British Journal of Cancer, 128(12), 2318-2325. Nature Publishing Group
Background: Only a subset of gastric cancer (GC) patients with stage II–III benefits from chemotherapy after surgery. Tumour infiltrating lymphocytes per area (TIL density) has been suggested as a potential predictive biomarker of chemotherapy bene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d6ab45673e7601c5aa45e30593e3fe
https://doi.org/10.1038/s41416-023-02257-3
https://doi.org/10.1038/s41416-023-02257-3
Autor:
Robin F. Irvine
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 11, Pp 1987-1994 (2016)
The diverse family of inositol lipids is now known to be central to many aspects of cell biology. The route from the first discovery of inositol to our present day knowledge of inositol lipids spans more than 150 years and is long and complex. This i
Externí odkaz:
https://doaj.org/article/78cfe1fd9caa4254b6086f1fedd83a7d
Autor:
Ismael Al-Ramahi, Sai Srinivas Panapakkam Giridharan, Yu-Chi Chen, Samarjit Patnaik, Nathaniel Safren, Junya Hasegawa, Maria de Haro, Amanda K Wagner Gee, Steven A Titus, Hyunkyung Jeong, Jonathan Clarke, Dimitri Krainc, Wei Zheng, Robin F Irvine, Sami Barmada, Marc Ferrer, Noel Southall, Lois S Weisman, Juan Botas, Juan Jose Marugan
Publikováno v:
eLife, Vol 6 (2017)
The discovery of the causative gene for Huntington’s disease (HD) has promoted numerous efforts to uncover cellular pathways that lower levels of mutant huntingtin protein (mHtt) and potentially forestall the appearance of HD-related neurological d
Externí odkaz:
https://doaj.org/article/da11075a98b347ab84cdded4b0780b44
Publikováno v:
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-17 (2020)
BMC Medical Research Methodology
BMC Medical Research Methodology
Background Meta-analyses of studies evaluating survival (time-to-event) outcomes are a powerful technique to assess the strength of evidence for a given disease or treatment. However, these studies rely on the adequate reporting of summary statistics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730b250c4a0b5ad7c97a5924cc59a146
http://link.springer.com/article/10.1186/s12874-020-01092-x
http://link.springer.com/article/10.1186/s12874-020-01092-x
Autor:
Sian F. Irvine, Jessica C. F. Kwok
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1172 (2018)
Perineuronal nets (PNNs) are extracellular matrix structures surrounding neuronal sub-populations throughout the central nervous system, regulating plasticity. Enzymatically removing PNNs successfully enhances plasticity and thus functional recovery,
Externí odkaz:
https://doaj.org/article/9dbab8a1a6554c668e077d7e7bffb02b
Publikováno v:
Open Biology, Vol 5, Iss 11 (2015)
Indirect assays have claimed to quantify phytate (InsP6) levels in human biofluids, but these have been based on the initial assumption that InsP6 is there, an assumption that our more direct assays disprove. We have shown that InsP6 does not and can
Externí odkaz:
https://doaj.org/article/e6d65de121ca454983ce44fca320f6eb
Publikováno v:
Open Biology, Vol 5, Iss 3 (2015)
Inositol phosphates are a large and diverse family of signalling molecules. While genetic studies have discovered important functions for them, the biochemistry behind these roles is often not fully characterized. A key obstacle in inositol phosphate
Externí odkaz:
https://doaj.org/article/3c8e3503ab624aa08539e3344d11926b